SavedAdd your journal

Journals / Damar Cerrahi Dergisi / 2000 / Cilt: 9 - Sayı: 3

The effect of trimetazidine in experimental renal ischemia-reperfusion

Renal iskemi-reperfüzyon hasarının azaltılmasında trimetazidinin rolü: Deneysel çalışma

İbrahim H. ÖZERCAN
Ali RAHMAN
Bilal ÜSTÜNDAĞ
Oktay BURMA
Ahmet ÇEKİRDEKÇİ
İhsan S. UYAR
Pages
1–6
Publication Date
2022-10-10
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

After 24 h of reperfusion, the MDA levels significantly increased (Group I: p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The effect of ischemia reperfusion on kidneys, tissue malondialdehyde (MDA) concentration, Gluthatıon Peroxidase (GSH-Px) and Superoxide Dismutase (SOD) activities were measured in 20 rats subject to occlusion of the left reanal artery for 60 min followed by 24 hours reperfusion.
📊
Key Findings & Data:The animals were separated in two equal groups: Group I (control) and Group II (TMZ).
💡
Conclusion & Impact:After 24 h of reperfusion, the MDA levels significantly increased (Group I: p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The effect of ischemia reperfusion on kidneys, tissue malondialdehyde (MDA) concentration, Gluthatıon Peroxidase (GSH-Px) and Superoxide Dismutase (SOD) activities were measured in 20 rats subject to occlusion of the left reanal artery for 60 min followed by 24 hours reperfusion. The animals were separated in two equal groups: Group I (control) and Group II (TMZ). A right nephrectomy was performed at the beginning of the ischemic period for control on each groups. After 24 h, tissue samples were taken for histopathological and biochemically examination. After 24 h of reperfusion, the MDA levels significantly increased (Group I: p

Özet

Renal iskemi-reperfüzyon (İ-R) hasarını değerlendirmek üzere 60 dakika iskemiyi takiben 24 saatlik reperfüzyon uygulanan ratlarda böbrek dokusu Malondialdehid (MDA) konsantrasyonu, glutatyon peroksidaz (GSH-Px) ve süperoksit dismutaz (SOD) aktiviteleri belirlendi. Yirmi rat kontrol (Grup I) ve trimetazidin -TMZ- (Grup II) olarak 2 eşit gruba ayrıldı. Kontrol değerler için iskemi öncesinde sağ nefrektomi yapıldı. 24. saatte histopatolojik-biyokimyasal inceleme için sol böbrek çıkarıldı. MDA düzeyleri 24. saatte arttı (Grup I: p

🔖

Cite This Article

ÖZERCAN, İ. H., RAHMAN, A., ÜSTÜNDAĞ, B., BURMA, O., ÇEKİRDEKÇİ, A., UYAR, İ. S. (2022). The effect of trimetazidine in experimental renal ischemia-reperfusion. Damar Cerrahi Dergisi, Cilt: 9 - Sayı: 3, 1–6. https://ajindex.com/articles/486921

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...