Journals / Çukurova Üniversitesi Tıp Fakültesi Dergisi / 2016 / Cilt: 41 - Sayı: 4

İstanbul'da human bocavirüs enfeksiyonu

Human bocavirus infection inİstanbul

Pages
762–766
Publication Date
2022-10-10
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Since there is lack of data investigating the frequency of HBoV respiratory tract infections in our region, our study has importance for providing new data

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: Human bocavirus (HBoV) is a recently discovered virus which is a member of Parvoviridae family.
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Key Findings & Data:Material and Methods: Hospitalized children aged 1-56 months with the diagnosis of lower respiratory tract infection (LRTI) were included in this prospective study between February 1st 2009 and May 21st 2009.
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Conclusion & Impact:Since there is lack of data investigating the frequency of HBoV respiratory tract infections in our region, our study has importance for providing new data
🔬Design:Research Article
📍Scope:2009 Verileri
⚙️Variables:Domain Parameters

Abstract

Purpose: Human bocavirus (HBoV) is a recently discovered virus which is a member of Parvoviridae family. It is mostly detected in respiratory tract and stool specimens in pediatric patients with the diagnosis of acute respiratory tract infections and gastroenteritis, respectively. Material and Methods: Hospitalized children aged 1-56 months with the diagnosis of lower respiratory tract infection (LRTI) were included in this prospective study between February 1st 2009 and May 21st 2009. HBoV DNA was investigated by PCR method. A questionarrie form was applied for all of the patients. Written informed consent of a parent or legal guardian was required Results: Among the total of 120 hospitalized children who were investigated for HBoV the mean age was 9.9 months (1-56 months). HBoV DNA PCR in nasopharyngeal swabs was positive in 8 (6.7%) of 120 patients. In HBoV (+) lower respiratory tract infection group, to have an ill subling with similar symptoms and number of sublings (>=3 or more) were found to be risk factors. In HBoV (+) group serum level of C-reactive protein was significantly lower than HBoV (-) group. Conclusion: The clinical spectrum of HBoV infection ranges from no symptoms or mild respiratory symptoms to severe acute respiratory disease. Since there is lack of data investigating the frequency of HBoV respiratory tract infections in our region, our study has importance for providing new data

Özet

Amaç: İnsan Bocavirüsü (HBoV) Parvoviridae ailesinden yeni keşfedilmiş bir virüstür. Çoğunlukla çocuk hastalarda solunum yolu ve dışkı örneklerinde tespit edilir ve sırasıyla solunum yolu enfeksiyonlarına ve gastroenterit tablosuna neden olur. Gereç ve Yöntem: 1 Şubat 2009- 21 Mayıs 2009 tarihleri arasında alt solunum yolu enfeksiyonu (ASYE) nedeniyle hastaneye yatırılan, yaşları 1-59 ay arasında değişen 120 çocuk bu prospektif çalışmaya dahil edildi. Hastaların solunum örneklerinden PCR yöntemi ile HBoV DNA'sı araştırıldı. Tüm hastalara risk faktörlerini belirlemek amacıyla anket uygulandı. Çocukların ailelerinden ya da yasal bakıcılarından yazılı onam formu alındı. Bulgular: Çalışmaya alınan hastaların yaş ortalaması 9.9 ay (1-56 ay) idi. 120 hastanın 8 (%6.7)'inde nazofarengeal aspirat örneğinde PCR yöntemiyle bakılan HBoV DNA pozitif olarak bulundu. HBoV (+) alt solunum yolu enfeksiyonu grubunda, benzer semptomlara sahip kardeşe sahip olmak ve kardeş sayısının >=3 ya da fazla olması risk faktörleri olarak belirlendi. HBoV (+) alt solunum yolu enfeksiyonu grubunda HBoV (-) alt solunum yolu enfeksiyonu grubuna göre serum C-reaktif protein (CRP) değerleri anlamlı olarak düşük bulundu. Sonuç: HBoV ile enfeksiyon bulguları, hiçbir klinik semptomun olmamasından ciddi akut solunum yolu enfeksiyonlarına kadar değişiklik gösterebilmektedir. Yeni keşfedilmiş bir virüs olması nedeniyle patojenitesi ve enfeksiyon için risk faktörlerini araştıran daha çok çalışmaya ihtiyaç vardır. Bölgemizde bu konu ile ilgili çok veri olmaması nedeniyle, çalışmamızın önemli bir kaynak olduğunu düşünmekteyiz

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Cite This Article

MİDİLLİ, K., AKIN, Y., CAMCIOĞLU, Y., KARAASLAN, A., DEMİRCİ, P. (2022). İstanbul'da human bocavirüs enfeksiyonu. Çukurova Üniversitesi Tıp Fakültesi Dergisi, Cilt: 41 - Sayı: 4, 762–766. https://ajindex.com/articles/485796

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