A weight loss of ≥ 10% was considered “significant”, and a weight loss of
📌 3 Key Takeaways
🎯
Objective & Hypothesis:Objective: To examine the association of weight loss achieved through obesity treatment with platelet number and markers (mean platelet volume, MPV; plateletcrit, PCT; platelet/lymphocyte ratio, PLR; and platelet distribution width, PDW) in morbidly obese patients.
📊
Key Findings & Data:Methods: A total of 300 patients diagnosed with morbid obesity between 2017 and 2019 were included in this retrospective study.
💡
Conclusion & Impact:A weight loss of ≥ 10% was considered “significant”, and a weight loss of
🔬Design:Research Article
📍Scope:2017 Verileri
⚙️Variables:morbid obesity · plateletcrit · mean platelet volume
Abstract
Objective: To examine the association of weight loss achieved through obesity treatment with platelet number and markers (mean platelet volume, MPV; plateletcrit, PCT; platelet/lymphocyte ratio, PLR; and platelet distribution width, PDW) in morbidly obese patients. Methods: A total of 300 patients diagnosed with morbid obesity between 2017 and 2019 were included in this retrospective study. Weight at baseline and 6 months, body mass index (BMI), complete blood count (platelet, lymphocyte, plateletcrit, platelet/lymphocyte ratio, and platelet distribution width), and demographic data were evaluated. Results: A total of 300 morbidly obese patients with a BMI ≥ 40 kg/m2 were included. A weight loss of ≥ 10% was considered “significant”, and a weight loss of
ÖZTÜRK, G., AK, M. A., ERTOP, S. (2021). The Association Between Weight Loss and Platelet Markers in Morbidly Obese Patients. Dicle Tıp Dergisi, Cilt: 48 - Sayı: 4, 754–760. https://ajindex.com/articles/484927
Leitner DR, Frühbeck G, Yumuk V, et al. Obesity and type 2 diabetes:Two diseases with a need for combined treatment strategies-EASO can lead the way. Obes Facts. 2017; 10: 483-92
Rueda- Clausen CF, Ogunleye AA, Sharma AM. Health benefits of long-term weight-loss maintenance. Annu Rev Nutr. 2015; 35: 475-516 3. Flegal KM, Carroll MD, Ogden CL, Johnson CL. Prevalence and trends in obesity among US adults, 1999-2000. JAMA. 2002; 288: 1723-7
Samur G, Yıldız E. Obezite ve kardiyovasküler hastaliklar/hipertansiyon Sağlık Bakanlığı Yayın 2008
Nording H, Langer HF. Complement links platelets to innate immunity. Seminars in immunology. 2018; 37: 43-52
Mutlu H, A rtış T A, E rden A, et al. Alteration in mean platelet volume and platicrit values in patients with cancer that developed thrombosis. Clinical and Applied Thrombosis/Hemostasis. 2013; 19: 331-3
Gasparyan YA, Ayvazyan L, Mikhailidis DP, et al. Mean platelet volume:a link between thrombosis and inflammation. Current Pharmaceutical Design. 2011; 17: 47-58
Morange PE, Alessi MC. Thrombosis in central obesity and metabolic syndrome: mechanisms and epidemiology. Thromb Haemost. 2013; 110: 669-80
Coutinho T, Goel K, Corrêa de S á D, et al. Central obesity and survival in subjects with coronary artery disease: a systematic review of the literature and collaborative analysis with individual subject data. J Am Coll Cardiol. 2011; 57: 1877-86
Borch KH, Nyegaard C, Hansen JB, et al. Joint effects of obesity and body height on the risk of venous thromboembolism: The Tromsø Study. Arteriosclerosis, Thrombosis and Vascular Biology. 2011; 31: 1439–44
Butkiewicz AM, Kemona H, Dymicka-Piekarska V, et al.Platelet count, mean platelet volume and thrombocytopoietic indices in healthy women and men. Thrombosis Research. 2006; 118: 199-204
Samocha-Bonet D, Justo D, Rogowski O, et al. Platelet counts and platelet activation markers in obese subjects. Mediators of inflammation 2008
Lebedeva EV,Yushkov BG, Chereshnev VA. Megakaryocytopoiesis under hypoxic conditions. Bulletin of Experimental Biology and Medicine. 2003; 136: 554-6
Greisenegger S, Endler G, Hsieh K, et al. Is elevated mean platelet volume associated with a worse outcome in patients with acute ischemic cerebrovascular events. Stroke. 2004; 35: 1688–91
Çoban E, Özdoğan M, Yazıcıoğlu G, et al. The mean platelet volume in patients with obesity. Int J Clin Pract. 2005; 59: 981-2