Journals / Dicle Tıp Dergisi / 2022 / Cilt: 49 - Sayı: 1

The Measurement of Neutrophil Gelatinase Associated Lipocalin in Umbilical Cord Blood and the Assessment of Its Relationship with Neonatal Results

Dicle Üniversitesi Yanık Merkezinde 2011-2020 Yılları Arasında Tedavi Edilen Yanık Hastalarının Epidemiyolojik Olarak İncelenmesi

Pages
229–235
Publication Date
2022-03-11
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, studies on larger patient populations are needed.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: In this study, the relationship of cord blood Neutrophil Gelatinase-Associated Lipocalin (NGAL) with neonatal diseases was investigated.
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Key Findings & Data:Methods: NGAL levels were measured in the cord blood of 180 babies born between 2015 and 2016.
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Conclusion & Impact:However, studies on larger patient populations are needed.
🔬Design:Research Article
📍Scope:2015 Verileri
⚙️Variables:Epidemiyolojik çalışma · Yanık tedavisi · Yanık

Abstract

Objectives: In this study, the relationship of cord blood Neutrophil Gelatinase-Associated Lipocalin (NGAL) with neonatal diseases was investigated. Methods: NGAL levels were measured in the cord blood of 180 babies born between 2015 and 2016. Patients were classified according to maternal diseases, neonatal diseases and demographic characteristics. Obtained data were compared with cord blood NGAL levels. Results: In our study, the mean NGAL levels were 1283.99 ng/mL in boys and 1306.52 ng/mL in girls. Umbilical cord blood NGAL levels of infants diagnosed with intrauterine growth retardation (1913.4±2833.5 ng/mL) and prolonged premature rupture of membranes (2594.2±2037.1 ng/mL) were found to be statistically high (p0.05). Conclusions: Neutrophil Gelatinase-Associated Lipocalin, may be useful as a diagnostic biomarker in the evaluation of maternal and neonatal diseases. However, studies on larger patient populations are needed.

Özet

Amaç: Bu çalışmanın amacı 2011 yılının Ocak ayından 2020 yılının Aralık ayı bitimine kadar, yanık merkezimizde tedavi edilen yanık hastalarına ait kayıtların epidemiyolojik olarak incelenmesidir. Yöntemler: Bu tanımlayıcı ve kesitsel türdeki çalışma Dicle Üniversitesi Tıp Fakültesi Hastanesi Yanık Merkezinde, retrospektif olarak gerçekleştirildi. 2011-2020 yılları arasında yanık vakaları elektronik hasta kayıtlarından elde edildi ve incelendi. İstatistiksel analizler Statistical Package for Social Sciences for IBM 25 paket programı ile yapıldı. Veri değerlendirmesinde tanımlayıcı istatistik yöntemleri (sayı, yüzde ve aritmetik ortalama vb) ve ki kare testi kullanıldı. Bulgular: Çalışmamızın örneklemini oluşturan 3227 yanık hastasının %55,3’ü 1-5 yaş aralığında ve %52,5’inin erkek olduğu belirlendi. Vakaların %42,7’si 2011-2013 yılları arasında gerçekleşmiştir. Yanıkların %64,1’inin sıcak sıvı yanığı, %50,4’ünün ikinci derece yanık olduğu saptandı. En fazla yanık vakası 2011-2013’te görülmüş ve vakalar 2020’ye doğru azalma göstermiştir. Yanık yaralanmasından en çok etkilenen yaş aralığının 1-5 arası ve en yüksek oranda yanık nedeninin sıcak sıvılar olduğu belirlendi (χ2 =5,560, p

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Cite This Article

AKKOÇ, M. F., ÖZDEMİR, M. (2022). The Measurement of Neutrophil Gelatinase Associated Lipocalin in Umbilical Cord Blood and the Assessment of Its Relationship with Neonatal Results. Dicle Tıp Dergisi, Cilt: 49 - Sayı: 1, 229–235. https://ajindex.com/articles/484882

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