Relationship Between Acute Appendicitis and Platelet Indices in Childhood

A receiver operating characteristic (ROC)curve was drawn to describe the parameters that may be statisticallysignificant.Results: There was a significant difference in platelet distributionwidth and mean platelet volume values between the two groups(p14.3 fL for platelet distribution width for the diagnosis of appendicitiswith a sensitivity, specificity, positive predictive value, and negativepredictive value of 77.6%, 85.8%, 96.3%, and 44.6%, respectively.

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: Appendicitis is the inflammation of the appendixvermiformis.

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Key Findings & Data:In this study, we aimed to investigate whether plateletdistribution width values and mean platelet volume were decisive forthe diagnosis of appendicitis in children.Methods: In our hospital, 504 pediatric patients who presentedwith acute abdomen and received the diagnosis of acute appendicitisbetween 2011 and 2016, and 106 children living in the same region,who attended the pediatric outpatient clinics for general followup,were included in the study.

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Conclusion & Impact:A receiver operating characteristic (ROC)curve was drawn to describe the parameters that may be statisticallysignificant.Results: There was a significant difference in platelet distributionwidth and mean platelet volume values between the two groups(p14.3 fL for platelet distribution width for the diagnosis of appendicitiswith a sensitivity, specificity, positive predictive value, and negativepredictive value of 77.6%, 85.8%, 96.3%, and 44.6%, respectively.

🔬Design:Research Article

📍Scope:2011 Verileri

⚙️Variables:Domain Parameters

Abstract

Introduction: Appendicitis is the inflammation of the appendixvermiformis. Clinical diagnosis of acute appendicitis in children is still aproblem. Platelet indices, platelet distribution width and mean plateletvolume have been evaluated for some infectious and inflammatorydiseases. In this study, we aimed to investigate whether plateletdistribution width values and mean platelet volume were decisive forthe diagnosis of appendicitis in children.Methods: In our hospital, 504 pediatric patients who presentedwith acute abdomen and received the diagnosis of acute appendicitisbetween 2011 and 2016, and 106 children living in the same region,who attended the pediatric outpatient clinics for general followup,were included in the study. The patient and control groups wereanalyzed for gender, age, platelet count, platelet distribution widthand mean platelet volume. A receiver operating characteristic (ROC)curve was drawn to describe the parameters that may be statisticallysignificant.Results: There was a significant difference in platelet distributionwidth and mean platelet volume values between the two groups(p14.3 fL for platelet distribution width for the diagnosis of appendicitiswith a sensitivity, specificity, positive predictive value, and negativepredictive value of 77.6%, 85.8%, 96.3%, and 44.6%, respectively. Acut-off value of

Özet

Giriş: Apandisit appendiks vermiformisin iltihaplanmasıdır. Akut apandisitin klinik tanısı çocuklarda hala bir problemdir. Trombosit indeksleri, ortalama trombosit dağılım genişliği ve trombosit hacmi, bazı enfeksiyöz ve enflamatuvar hastalıklar için değerlendirilmiştir. Bu çalışmada, çocuklarda apandisit tanısı için ortalama trombosit dağılım genişliği ve trombosit hacmi değerlerinin belirleyici olup olmadığını araştırmayı amaçladık. Yöntemler: Hastanemizde, 2011-2016 yılları arasında akut karın nedeniyle akut apandisit tanısı alan 504 çocuk ve aynı bölgede yaşayan sağlam çocuk polikliniğine genel takip için başvuran 106 çocuk çalışmaya alındı. Hasta ve kontrol grupları cinsiyet, yaş, trombosit sayısı, ortalama trombosit dağılım genişliği ve trombosit hacmi açısından analiz edildi. Apandisitte istatistiksel olarak anlamlı olabilecek parametreleri tanımlamak için bir alıcı işletim karakteristiği eğrisi [Receiver Operating Characteristic (ROC)] çizildi. Bulgular: Trombosit dağılım genişliği ve ortalama trombosit hacmi değerlerinde iki grup arasında anlamlı fark saptandı (p14,3 fL trombosit dağılım genişliği eşik değeri için, apandisit tanısında duyarlılık, özgüllük, pozitif öngörü değer ve negatif öngörü değeri sırasıyla %77,6, %85,8, %96,3 ve %44,6 olarak bulunurken ortalama trombosit hacmi için

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Cite This Article

CESUR, İ. B., ÖZÇELİK, Z., REŞİTOĞLU, S., SUCU, A., ÇELİK, Ü., ÇELİK, T., TOLUNAY, O. (2022). Relationship Between Acute Appendicitis and Platelet Indices in Childhood. Çocuk Acil ve Yoğun Bakım Dergisi, Cilt: 5 - Sayı: 2, 64–68. https://ajindex.com/articles/483806

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