Journals / Çocuk Acil ve Yoğun Bakım Dergisi / 2022 / Cilt: 9 - Sayı: 1

Diagnosis and Treatment Approach in Methanol Poisoning: A Case Report

Metanol İntoksikasyonunda Tanı ve Tedavi Yaklaşımı: Olgu Sunumu

Pages
55–58
Publication Date
2022-10-11
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this article, a 17-year-old male patient who was admitted to the pediatric emergency department with vomiting, abdominal pain and deep metabolic acidosis and learned to have produced alcoholic beverages at home was presented.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Methyl alcohol is an alcohol derivative that is widely used in the industry and is easy to obtain.
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Key Findings & Data:Methyl alcohol intoxication is a serious condition that has a high mortality risk and can cause metabolic acidosis, vision loss, and central nervous system suppression.
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Conclusion & Impact:In this article, a 17-year-old male patient who was admitted to the pediatric emergency department with vomiting, abdominal pain and deep metabolic acidosis and learned to have produced alcoholic beverages at home was presented.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Methyl alcohol is an alcohol derivative that is widely used in the industry and is easy to obtain. Methyl alcohol intoxication is a serious condition that has a high mortality risk and can cause metabolic acidosis, vision loss, and central nervous system suppression. Bicarbonate can be given in the treatment of metabolic acidosis, as well as hemodialysis to remove toxic metabolites. Ethanol or fomepizole can be used to reduce toxic effects by competitive inhibition. In this article, a 17-year-old male patient who was admitted to the pediatric emergency department with vomiting, abdominal pain and deep metabolic acidosis and learned to have produced alcoholic beverages at home was presented.

Özet

Metil alkol sanayi sektöründe yaygın olarak kullanılan ve elde edilmesi kolay bir alkol türevidir. Metil alkol zehirlenmesi yüksek oranda ölüm riski taşıyan, metabolik asidoz, görme kaybı, santral sinir sistemi baskılanmasına neden olabilen ciddi bir tablodur. Metabolik asidozun tedavisinde bikarbonat verilebilir, aynı zamanda toksik metabolitleri de uzaklaştırmak için hemodiyaliz uygulanabilir. Etanol veya fomepizol yarışmalı inhibisyon yolu ile toksik etkilerin azaltılması için kullanılabilir. Bu makalede çocuk acil servise kusma karın ağrısı ve derin metabolik asidoz ile başvuran ve evde kendi olanakları ile alkollü içecek ürettiği öğrenilen 17 yaşında erkek olgu sunulmuştur.

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Cite This Article

ERDAL, M., SİVİL, N., ÇEBİŞLİ, E., TEKEREK, N. Ü., KENDİR, Ö. T., DURSUN, O. (2022). Diagnosis and Treatment Approach in Methanol Poisoning: A Case Report. Çocuk Acil ve Yoğun Bakım Dergisi, Cilt: 9 - Sayı: 1, 55–58. https://ajindex.com/articles/483720

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References (15)

  1. Fein DM, Sue YJ. Methanol ingestion. Pediatr Rev. 2011;32:549-50
  2. Yayci N, Ağritmiş H, Turla A, Koç S. Fatalities due to methyl alcohol intoxication in Turkey: an 8-year study. Forensic Sci Int. 2003;131:36-41
  3. Chen TH, Kuo CH, Huang CT, Wang WL. Use of Fomepizole in Pediatric Methanol Exposure: The First Case Report in Taiwan and a Literature Review. Pediatr Neonatol. 2016;57:351-4
  4. McMahon DM, Winstead S, Weant KA. Toxic alcohol ingestions: focus on ethylene glycol and methanol. Adv Emerg Nurs J. 2009;31:206-13
  5. Liesivuori J, Savolainen H. Methanol and formic acid toxicity: biochemical mechanisms. Pharmacol Toxicol. 1991;69:157-63
  6. Barceloux DG, Bond GR, Krenzelok EP, Cooper H, Vale JA; American Academy of Clinical Toxicology Ad Hoc Committee on the Treatment Guidelines for Methanol Poisoning. American Academy of Clinical Toxicology practice guidelines on the treatment of methanol poisoning. J Toxicol Clin Toxicol. 2002;40:415-46
  7. Cervantes CE, Chu A, Heller D, Lemont M. Early dialysis in a rare case of combined toxic alcohols ingestion. CEN Case Rep. 2020;9:11-4
  8. Bergeron R, Cardinal J, Geadah D. Prevention of methanol toxicity by ethanol therapy. N Engl J Med. 1982;307:1528
  9. Sanaei-Zadeh H, Zamani N, Shadnia S. Outcomes of visual disturbances after methanol poisoning. Clin Toxicol (Phila). 2011;49:102-7
  10. Burns MJ, Graudins A, Aaron CK, McMartin K, Brent J. Treatment of methanol poisoning with intravenous 4-methylpyrazole. Ann Emerg Med. 1997;30:829-32
  11. Hassanian-Moghaddam H, Zamani N, Roberts DM, Brent J, McMartin K, et al. Consensus statements on the approach to patients in a methanol poisoning outbreak. Clin Toxicol (Phila). 2019;57:1129-36
  12. Hovda KE, Hunderi OH, Tafjord AB, Dunlop O, Rudberg N, et al. Methanol outbreak in Norway 2002-2004: epidemiology, clinical features and prognostic signs. J Intern Med. 2005;258:181-90
  13. Zakharov S, Pelclova D, Navratil T, Belacek J, Komarc M, et al. Fomepizole versus ethanol in the treatment of acute methanol poisoning: Comparison of clinical effectiveness in a mass poisoning outbreak. Clin Toxicol (Phila). 2015;53:797-806
  14. Yaycı N, İnanıcı MA. Metil alkol (metanol) zehirlenmesi. Türkiye Klinikleri J Foren Med. 2005;2:101-8
  15. Zakharov S, Rulisek J, Nurieva O, Kotikova K, Navratil T, et al. Intermittent versus continuous renal replacement therapy in acute methanol poisoning: comparison of clinical effectiveness in mass poisoning outbreaks. Ann Intensive Care. 2017;