Journals / Clinical and Experimental Health Sciences / 2015 / Cilt: 5 - Sayı: 4

Importance of Vitamin D and Its Receptor in Sportsman Health and Athletic Performance

Sporcu Sağlığı ve Atletik Performansta D Vitamini ve Reseptörünün Önemi

Pages
259–264
Publication Date
2015-12-29
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Therefore, we hope that this review will help scientists to have a general information about vitamin D and athlete health and performance; also will guide for further studies.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Vitamin D is an important molecule which regulates many reactions in different tissues and organs, and also can be named as hormone.
📊
Key Findings & Data:Blood 25-hydroxy vitamin D is the main metabolite that determines the individuals vitamin D levels.
💡
Conclusion & Impact:Therefore, we hope that this review will help scientists to have a general information about vitamin D and athlete health and performance; also will guide for further studies.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:D vitamini · spor · atletik performans

Abstract

Vitamin D is an important molecule which regulates many reactions in different tissues and organs, and also can be named as hormone. It can be synthesized either endogenously under UV light or exogenously by diet. Vitamin D is converted to its active form after being metabolised by liver and kidney, respectively. Blood 25-hydroxy vitamin D is the main metabolite that determines the individuals vitamin D levels. Vitamin D deficiency may lead to many diseases like diabetes, various cancer types and cardiovascular problems. They affect the target organs by triggering their vitamin D receptors. Many studies were carried out regarding the polymorphisms on the receptor gene, and outlined the function of the gene. Studies on athletes in different sport types showed the importance of this vitamin for athletic performance. Studies including the vitamin D blood levels and polymorphisms on the encoding gene associated the athletic performance and vitamin D, and low vitamin D blood levels and sports injuries were came into prominence. Fok1, Bsm1, Taq1 and Apa1 are the main examined polymorphisms within the gene. In this review, we aimed to give brief information about vitamin D, and state the importance of vitamin D metabolism and its receptor in the terms of sportsmen health. Therefore, we hope that this review will help scientists to have a general information about vitamin D and athlete health and performance; also will guide for further studies.

Özet

D vitamini doku ve organlarda birçok metabolizmayı düzenleyen, hor¬mon olarak da adlandırılabilen önemli bir moleküldür. Endojen olarak sentezlenebildiği gibi eksojen olarak da dışarıdan diyetle alınabilir. Sırası ile karaciğer ve böbrekte metabolize edilerek aktif formuna çevrilir. Kan 25- hidroksivitamin D düzeyi bireylerin D vitamini hakkında bilgi vermektedir. Eksikliği diyabet, bazı kanser türleri ve kardiyovasküler sistem bozuklukları olarak karşımıza çıkabilmektedir. D vitamini etkisini D vitamini reseptörleri üzerinden gösterir. Reseptörü kodlayan gen üze¬rinde bulunan polimorfizmler ile ilgili birçok çalışma gerçekleştirilmiş ve polimorfizmlerin karakterizasyonu yapılmıştır. Farklı spor türlerindeki sporcular üzerinde yapılan çalışmalar ile atletik performans için önemi ortaya konmuştur. Bu çalışmalar D vitamininin kan düzeyleri veya resep¬tör üzerindeki polimorfizmler ile gerçekleştirilmiş ve atletik performans ile ilişkilendirilmiştir. Özellikle vitaminin kan düzeyleri düşük olan spor¬culardaki performans ve sporcu sakatlıkları ön plana çıkan çalışmalardır. Reseptör geni ile ilgili ise Fok1, Bsm1, Taq1 ve Apa1 polimorfizmleri ön plana çıkmıştır. Bu derlemede D vitamini metabolizması hakkında genel bilgi verilip, sporcu sağlığı için D vitamini metabolizmasının ve resep¬törünün önemi vurgulamıştır. Böylece sporcular ile yapılabilecek yeni çalışmalara zemin hazırlanması amaçlanmıştır.

🔖

Cite This Article

SERCAN, C., YAVUZSOY, E., YUKSEL, İ., CAN, R., OKTAY, S., KIRAC, D., ULUCAN, K. (2015). Importance of Vitamin D and Its Receptor in Sportsman Health and Athletic Performance. Clinical and Experimental Health Sciences, Cilt: 5 - Sayı: 4, 259–264. https://ajindex.com/articles/481742

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (18)

  1. Holick MF. Vitamin D deficiency. N Engl J Med. 2007;357: 266-281
  2. Holick MF. Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. Am J Clin Nutr. 2004; 80(Suppl.): 1678S-1688S
  3. Sözen T. D hormonu: Güncel gelişmeler. Hacettepe Tıp Dergisi. 2011; 42: 14-27
  4. Fidan F, Alkan BM, Tosun A. Çağın Pandemisi: D Vitamini Eksikliği ve Yetersizliği. Türk Osteoporoz Dergisi. 2014; 20: 71-74
  5. Naylora AJD, Edwardsb SL, The effects of vitamin D on skeletal muscle function and cellular signaling. The Journal of steroid biochemistry and molecular biology. 2011; 159-168
  6. Wacker M, Holick MF. Vitamin D-Effects on Skeletal and Extraskeletal Health and the Need for Supplementation. Nutrients 2013; 5: 111-148
  7. Trang H, Cole DE, Rubin LA, Pierrtos A, Siu S, Vieth R. Evidence that VD3 increases serum 25hydroxyvitamin D more efficiently than does Vitamin D2. Am J Clin Nutr. 1998; 68: 854-858
  8. De Luca HF, Cantorna MT. Vitamin D: its role and uses in immunology. FASEB J. 2001; 15: 2579-2585
  9. Hamilton B. Vitamin D and Athletic Performance. The Potential Role of Muscle. Asian Journal of Sports Medicine. 2011; 2(4): 211-219
  10. Öngen B, Kabaroglu C, Parıldar Z. D Vitamini’nin Biyokimyasal ve Laboratuvar Değerlendirmesi. Türk Klinik Biyokimya Derg. 2008; 6(1): 23-31
  11. Dawson-Hughes B, Heaney RP, Holick MF, Ips P, Meunier PJ, Vieth R. Estimates of optimal vitamin D status. Osteoporos Int 2005; 16: 713- 716
  12. Vieth R, Vitamin D supplementation, 25-hydroxyvitamin D concentration, and safety. Am J Clin Nutr. 1999; 69: 842-856
  13. Mosekilde L. Vitamin D and the elderly. Clin Endocrinol. 2005; 62: 265- 281
  14. Grant WB, Soles CM. Epidemiologic evidence supporting the role of maternal vitamin D deficiency as a risk factor for the development of infantile autism. Dermatoendocrinol. 2009; 1(4): 223-228
  15. Halliday T, Peterson N, Thomas J, Kleppinger K, Hollis BW, Larson-Meyer DE. Vitamin D status relative to diet, lifestyle, injury, and illness in college athletes. Med Sci Sports Exerc. 2011; 43: 335-343
  16. Robertson S, Benardot D, Mountjoy M. Nutritional recommendations for synchronized swimming. Int J Sport Nutr Exerc Metab. 2014; 24(4): 404-413
  17. Andersen R, Molgaard C, Skovgaard L, et al. Teenage girls and elderly women living in northern Europe have low winter vitamin D status. Euro J Clin Nutr. 2005; 1-9
  18. Larson-Meyer DE, Willis KS. Vitamin D and Athletes. Current Sports Medicine Repo