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Journals / Cumhuriyet Science Journal / 2018 / Cilt: 39 - Sayı: 3

Synthesis and Biological Evaluation of Novel 5,8-Dibromo-2-N-substituted-1,4-Naphthoquinone Derivatives as Potential Antimicrobial Agents

Potansiyel Antimikrobiyal Ajanlar Olarak Yeni 5,8-Dibromo-2-N-Sübstitüe-1,4-Naftokinon Türevlerinin Sentezi ve Biyolojik Değerlendirmesi

Kıymet BERKİL AKAR
Bilge Hilal ÇADIRCI
Eda MERCAN
Barış ERAN
Pages
608–614
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The results suggest that the synthesized 2-N-substituted-1,4-naphthoquinoneshave high antimicrobial activity.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The seven 5,8-dibromo-2-N-substituted-1,4-naphthoquinonederivatives have been synthesized and tested for their in vitro antimicrobialactivities.
📊
Key Findings & Data:The results suggest that the synthesized 2-N-substituted-1,4-naphthoquinoneshave high antimicrobial activity.
💡
Conclusion & Impact:The diffusion capacities of the compounds arealso important for the determination of the antimicrobial activities; 2c, 2f and 2g have beenshown to be promising compounds for future studies.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The seven 5,8-dibromo-2-N-substituted-1,4-naphthoquinonederivatives have been synthesized and tested for their in vitro antimicrobialactivities. The results suggest that the synthesized 2-N-substituted-1,4-naphthoquinoneshave high antimicrobial activity. The diffusion capacities of the compounds arealso important for the determination of the antimicrobial activities; 2c, 2f and 2g have beenshown to be promising compounds for future studies.

Özet

Yedi adet 5,8-dibromo-2-N-sübstitüe-1,4-naftakinon türevi sentezlenmiş ve bu bileşiklerin in vitro antimikrobiyal aktiviteleri test edilmiştir. Elde edilen sonuçlar 2-N-sübstite-1,4-naftakinonların yüksek antimikrobiyal etkinliğe sahip olduklarını göstermektedir. Bileşiklerin difüzyon kapasitesi de antimikrobiyal aktivitelerin belirlenmesinde önem taşımaktadır; Sonuçlar 2c, 2f ve 2g bileşiklerinin gelecekteki çalışmalar için umut verici bileşikler olduklarını ortaya koymuştur.

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Cite This Article

AKAR, K. B., ÇADIRCI, B. H., MERCAN, E., ERAN, B. (2022). Synthesis and Biological Evaluation of Novel 5,8-Dibromo-2-N-substituted-1,4-Naphthoquinone Derivatives as Potential Antimicrobial Agents. Cumhuriyet Science Journal, Cilt: 39 - Sayı: 3, 608–614. https://ajindex.com/articles/477968

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