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Journals / Cumhuriyet Science Journal / 2018 / Cilt: 39 - Sayı: 1

Induced Genotoxicity in Human Lymphocytes by Neonicotinoids

Neonikotinoidler ile İnsan Lenfositlerinde Genotoksisitenin Uyarılması

Handan UYSAL
Halit KIZILET
Pages
201–210
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As a result, an increase in SCE frequency depending on the increased concentration was observed in all treatment groups of both insecticides (P

📌 3 Key Takeaways

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Objective & Hypothesis:In this study, genotoxic effects of imidacloprid (IMI) and acetamiprid (ASE) from neonicotinoid group insecticides were investigated in the human peripheral lymphocyte cells with the Sister Chromatid Exchange Test (SCE).
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Key Findings & Data:IMI (50, 100, 250 and 500 ppm) and ACE (25, 50, 100 and 250 ppm) insecticides were added to the culture medium at different concentrations in order to determine the genotoxicity of the insecticides.
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Conclusion & Impact:As a result, an increase in SCE frequency depending on the increased concentration was observed in all treatment groups of both insecticides (P
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In this study, genotoxic effects of imidacloprid (IMI) and acetamiprid (ASE) from neonicotinoid group insecticides were investigated in the human peripheral lymphocyte cells with the Sister Chromatid Exchange Test (SCE). Water and methanol extracts of Portulaca oleracea L. (Purslane) plant were used to eliminate the possible genotoxic effects of these substances. IMI (50, 100, 250 and 500 ppm) and ACE (25, 50, 100 and 250 ppm) insecticides were added to the culture medium at different concentrations in order to determine the genotoxicity of the insecticides. As a result, an increase in SCE frequency depending on the increased concentration was observed in all treatment groups of both insecticides (P

Özet

Bu çalışmada, neonikotinoid grubu insektisitlerden imidakloprid (İMİ) ve asetamiprid (ASE)'in genotoksik etkileri insane peripheral lenfosit hücrelerinde Kardeş Kromatid Değişim Testi (KKD) ile araştırılmıştır. Bu maddelerin olası genotoksik etkilerinin giderilebilmesi için de Portulaca oleracea L. (Semizotu) bitkisine ait su ve methanol ekstreleri kullanılmıştır. İnsektisitlere ait genotoksisitenin belirlenmesi amacıyla kültür ortamına farklı konsantrasyonlarda İMİ (50, 100, 250 ve 500 ppm) ve ASE (25, 50, 100 ve 250 ppm) insektisitleri ilave edilmiştir.Yapılan incelemeler sonucu, her iki insektisitin artan konsantrasyonuna bağlı olarak tüm uygulama gruplarında KKD frekansında artış gözlenmiştir (P

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Cite This Article

UYSAL, H., KIZILET, H. (2022). Induced Genotoxicity in Human Lymphocytes by Neonicotinoids. Cumhuriyet Science Journal, Cilt: 39 - Sayı: 1, 201–210. https://ajindex.com/articles/477939

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References (2)

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