Journals / Cumhuriyet Dental Journal / 2016 / Cilt: 19 - Sayı: 3

2 Çocuk Diş Hekimi, Serbest Çalışan, İstanbul, Türkiye

A General Outlook to Regenerative Pulp Therapy

Pages
238–246
Publication Date
2022-10-11
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, regenerative endodontic treatment prodedures, materials and developments are discussed in detail.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Withing the last 10 years, the research regarding stem cell biology and tissue engineering has reaped many rewards in the field of dentistry.
📊
Key Findings & Data:The goal of regenerative endodontic therapy is the regeneration of a healthy and functional pulp-dentin complex.
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Conclusion & Impact:In this review, regenerative endodontic treatment prodedures, materials and developments are discussed in detail.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Withing the last 10 years, the research regarding stem cell biology and tissue engineering has reaped many rewards in the field of dentistry. The goal of regenerative endodontic therapy is the regeneration of a healthy and functional pulp-dentin complex. With the development of successful materials such as mineral trioxide aggregate (MTA) and the use of the concept of tissue engineering, treating necrotic immature permanent teeth and stimulating the continuation of root-surrounding tissue formation has been made possible. Current stem cell research has also shown promising results and continues to show progress in the regeneration of dental and surrounding tissue. Since the ethical aspect of the use of stem cells is still in question, we have yet to see the potential of these materials in clinical practice. In this review, regenerative endodontic treatment prodedures, materials and developments are discussed in detail.

Özet

Son 10 yıl içerisinde, kök hücre biyolojisi ve doku mühendisliği üzerine yapılan çalışmalar diş hekimliği alanını olumlu bir yönde etkilemiştir. Rejeneratif endodontik tedavinin amacı, sağlıklı ve fonksiyonel bir dentin-pulpa komplesinin yeniden oluşturulmasıdır. Mineral trioksit agregat (MTA) gibi başarı gösteren materyallerin ve doku mühendisliği konseptlerinin kullanılması ile kök gelişimini tamamlamamış nekroze dişlerin kök-çevre doku gelişimlerinin devam etmesi mümkün olmuştur. Kök hücreler ile yapılan çalışmalarda umut vaat eden sonuçlar elde edilmiş olup halen diş-çevre dokularının rejenerasyonunda olumlu gelişmeler kaydedilmektedir. Kök hücrelerin kullanımı etik olarak sorgulandığından, bu materyallerin klinik olarak etkisi henüz bilinmemektedir. Bu derleme çalışmasında, rejeneratif endodontik tedavi yöntemi, kullanılan materyaller ve bu alandaki güncel gelişmeler detaylı olarak ele alınmaktadır.

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Cite This Article

EKÇİ, E. S., ALTIN, K. T., GÜRDOĞAN, E. B., ŞENÖZ, D. (2022). 2 Çocuk Diş Hekimi, Serbest Çalışan, İstanbul, Türkiye. Cumhuriyet Dental Journal, Cilt: 19 - Sayı: 3, 238–246. https://ajindex.com/articles/477078

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References (13)

  1. Akgün ÖZ, Polat GG, Altun CA. Rejeneratif pulpa tedavilerinde doku mühendisliği uygulamaları. Klinik bilimler dergisi 2008;2(4):238-244
  2. Lesot H, Smith AJ, Tziafas D, Begue-Kirn C, Cassidy N, Ruch JV. Biologically active molecules and dental tissue repair: A comparative review of reactionary and reparative dentinogenesis with the induction of odontoblast differentiation in vitro. Cells Mater 1994; 4: 199-218
  3. Murray PE, Windsor U, Smyth TW, Hafez AA, Cox CF. Analysis of pulpal reactions to restorative procedures, materials, pulp capping and future therapies. Crit Rev Oral Biol Med 2002;33(4):377-390
  4. Sharma S, Sikri V, Sharma NK, Sharma VM. Regeneration of tooth pulp and dentin: trends and advances. Annals of neurosciences 2010;17(1):31-43
  5. Andreasen JO, Farik B, Munksgaard EC. Long-term calcium hydroxide as a root canal dressing may increase risk of root fracture. Dent Traumatol 2002;18:134-137
  6. Garcia-Godoy F, Murray PE. Recommandations for using regenerative endodontic procedures in permanent immature traumatized teeth. Dent Traumatol 2012;28:33- 41
  7. Kumar ARP, Subbiya A. Regenerative endodontic therapy on non-vital immature maxillary incisors: Working protocol and a case report. Journal of Interdiciplinary Dentistry 2011;1(1):55-57
  8. Kling M, Cvek M, Mejare I. Rate and predictability of pulp revascularization in therapeutically reimplanted permanent incisors. Endod Dent Traumatol 1986; 2: 83-9
  9. Reynolds K, Johnson JD, Cohenca N. Pulp revascularization of necrotic bilateral bicuspids using a modified novel technique to eliminate potential coronal discoloration: a case report. Int Endod J 2009;42:84- 92
  10. Jadhav GR, Shah N, Logani A. Platelet-rich plasma supplemented revascularization of an immature tooth associated with a periapical lesion in a 40-year-old man. Case reports in Dentistry 2014; 2014: 479584
  11. Hoshino E, Ando-Kurihara N, Sato I, Uematsu H, Sato M, Kota K, Iwaku M. In-vitro antibacterial susceptibility of bacteria taken from infected root dentine to a mixture of ciprofloxacin, metronidazole and minocycline. Int Endod J 1996;29:125-130
  12. Kim JH, Kim Y, Shin SJ, Park JW, Jung IY. Tooth discoloration of immature permanent incisor associated with triple antibiotic therapy: a case report. J Endod 2010;36:1086-1091
  13. Wang X, Thibodeau B, Trope M, Lin LM, Huang GT. Histologic characterization of regenerated tissues in canal space after the revitalization/revascularization procedure of immature dog teeth with a