AI Summary & Key Takeaways
AI InsightQuantitative and qualitative analyses of sennosides in the samples were performed by thin layer chromatography (TLC) and ultraviolet spectroscopy (UV) spectroscopy methods.Results: According to the results of the analysis, the samples were not found to be suitable as per the officinal drug standards in European Pharmacopoeia 7.0.Conclusion: According to the results of the quality control analysis, senna samples sold by akhtars were observed to be unsafe for the treatment of constipation.
📌 3 Key Takeaways
Abstract
Objective: The aim of this study was to perform quality control analysis of the plants sold as senna in the market.Methods: The samples obtained from akhtars were evaluated according to European Pharmacopoeia 7.0 standard. Macroscopic, microscopic, and quantitative microscopy (stomatal index) studies and total ash, loss on drying, ash insoluble in hydrochloric acid, and foreign matter analyses were performed in the samples. Quantitative and qualitative analyses of sennosides in the samples were performed by thin layer chromatography (TLC) and ultraviolet spectroscopy (UV) spectroscopy methods.Results: According to the results of the analysis, the samples were not found to be suitable as per the officinal drug standards in European Pharmacopoeia 7.0.Conclusion: According to the results of the quality control analysis, senna samples sold by akhtars were observed to be unsafe for the treatment of constipation.
Özet
Amaç: Bu çalışmanın amacı, piyasada “sinameki” olarak satılan bitkilerin kalite kontrollerinin yapılmasıdır.Yöntemler: Aktarlardan alınan örnekler Avrupa Farmakopesi 7,0 standartlarına göre değerlendirilmiştir. Bu örneklerde makroskobik, mikroskobik ve kantitatif mikroskobi (stoma indisi) çalışmaları, yabancı madde tayini, kurutmada kayıp, bütün kül miktar tayini ve asitte çözünmeyen kül tayini yapılmıştır. Örneklerdeki sennozitlerin kalitatif ve kantitatif analizleri ince tabaka kromatografisi (İTK) ve ultraviyole spektroskobisi (UV) yöntemleri ile yapılmıştır.Bulgular: Tüm analiz sonuçlarına göre, örneklerin Avrupa Farmakopesi 7,0’da yer alan tıbbi drog standartlarına uygun olmadığı bulunmuştur.Sonuç: Kalite kontrol analiz sonuçlarına göre, aktarlarda sinameki olarak satılan örneklerin kabızlık tedavisi için çok güvenilir olmadığı gözlenmiştir.