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Journals / Clinical and Experimental Health Sciences / 2021 / Cilt: 11 - Sayı: 4

The Determination of IL-6 rs1800795 Polymorphism Distribution in Turkish National Cross-Country Skiing Athletes Sub-groups Created Referring to the 1km CCSTAs

Sehkar Oktay
Tolga Polat
Korkut Ulucan
Beste Tacal Aslan
Basak Funda Eken
Derya Kazanci
Canan Sercan Dogan
Fatih Bilici
Omer Kaynar
Pages
782–786
Publication Date
2022-10-11
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

But we obtained the significant genotype distribution only in Group-3 (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Interleukin-6 (IL-6) is an effective and functional protein with a cytokine structure.
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Key Findings & Data:IL-6 is effective in the immune system like a pro/anti-inflammatory response, and muscle tissue hypertrophy and repair.
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Conclusion & Impact:But we obtained the significant genotype distribution only in Group-3 (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:IL-6 genotypes · cross-country skiing · endurance

Abstract

Objective: Interleukin-6 (IL-6) is an effective and functional protein with a cytokine structure. IL-6 is effective in the immune system like a pro/anti-inflammatory response, and muscle tissue hypertrophy and repair. Our study aimed to investigate the IL-6 rs1800795 polymorphism distribution in Turkish National Cross-Country Skiing Athletes and to determine the advantageous genotype for endurance performance. Methods: 34 athletes within 3 groups; General (Group-1), Women (Group-2), and Men (Group-3) were enrolled to the study. Also each groups were divided into sub-groups according to their “1-kilometer cross-country average skiing-times (1 km-CCSTAs)”. Blood samples were used for DNA isolation and genotyping were completed by real time- PCR. Results: The groups' 1 km-CCSTAs were 188.7 ± 22.4, 212.3 ± 17.8, and 177.4 ± 14.1 seconds, respectively. We detected the genotypes as 17 GG (50%) and 17 GC (50%) in Group-1; 5 GG (45%) and 6 GC (55%) in Group-2; 12 GG (52%) and 11 GC (48%) in Group- 3. We detected no CC genotype in groups. Chi-square Fisher’s test was used for statistical analysis. Conclusion: An increased GC genotype ratio was detected in the faster sub-groups of each group compared to the slower sub-groups. But we obtained the significant genotype distribution only in Group-3 (p

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Cite This Article

Oktay, S., Polat, T., Ulucan, K., Aslan, B. T., Eken, B. F., Kazanci, D., Dogan, C. S., Bilici, F., Kaynar, O. (2022). The Determination of IL-6 rs1800795 Polymorphism Distribution in Turkish National Cross-Country Skiing Athletes Sub-groups Created Referring to the 1km CCSTAs. Clinical and Experimental Health Sciences, Cilt: 11 - Sayı: 4, 782–786. https://ajindex.com/articles/474235

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