Journals / Cerrahpaşa Tıp Dergisi / 2009 / Cilt: 40 - Sayı: 2

Increased plasma carnitine levels in patients with liver cirrhosis

Karaciğer sirozlu hastalarda artmış plazma karnitin seviyeleri

Pages
41–44
Publication Date
2022-10-10
DOI
—
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The statistical analyses were performed by student's t test.Results: Total, free and acyl carnitine levels in all cirrhotic patients were higher than the? control group's levels (p

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Objective & Hypothesis:Objectives: Carnitine is an important essential colactor in transfer of long chain fatty acids ac ross the inner mitochondrial membrane.
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Key Findings & Data:The aim of this study was to investigate total, free and acyl carnitine levels in patients with liver cirrhosis in comparison with healthv subjects.Methods: A total 55(37 male /18 female) cirrhotic patients were; included in the study (33 compensated and 22 decompensated). 39 and 16 patients were; associated with HBV and HCV, respectively.
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Conclusion & Impact:The statistical analyses were performed by student's t test.Results: Total, free and acyl carnitine levels in all cirrhotic patients were higher than the? control group's levels (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: Carnitine is an important essential colactor in transfer of long chain fatty acids ac ross the inner mitochondrial membrane. The aim of this study was to investigate total, free and acyl carnitine levels in patients with liver cirrhosis in comparison with healthv subjects.Methods: A total 55(37 male /18 female) cirrhotic patients were; included in the study (33 compensated and 22 decompensated). 39 and 16 patients were; associated with HBV and HCV, respectively. The; control group consisted of 30 healthy persons. The statistical analyses were performed by student's t test.Results: Total, free and acyl carnitine levels in all cirrhotic patients were higher than the? control group's levels (p

Özet

Amaç: Karnitin zincirli yağ asitlerinin iç mitokondriyal membrandan geçişini sağlayan önemli bir kofaktördür. Çalışmanın amacı karaciğer sirozu olan erişkin hastalarda plazma total, serbest ve açil karnitin düzeylerini saptamak ve sonuçları sağlıklı kontroller ile değerlendirmektir.Yöntem: 33 kompanse ve 22 dekompanse olmak üzere 55 karaciğer sirozlu hasta(37 erkek, 18 kadın ) çalışmaya alındı. Hastaların etiyolojisi, sırasıyla 39 ve 16 hasta hepatit B ve C virüsü enfeksiyonu ile ilişkiliydi. Kontrol grup 50 sağlıklı bireyden oluştu. İstatistiksel analizler student t testi ile yapıldı.Bulgular: Plazma total, serbest ve açil karnitin düzeyleri tüm sirolik hastalarda kontrol gurubuna göre anlamlı olarak yüksekti (p

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Cite This Article

ÖZDEMİR, S., AKIN, P., BARAN, A., ZEYBEK, Ç. A., KAHVECİ, A., AYDIN, A., ÖNAL, H., YALVAÇ, S. (2022). Increased plasma carnitine levels in patients with liver cirrhosis. Cerrahpaşa Tıp Dergisi, Cilt: 40 - Sayı: 2, 41–44. https://ajindex.com/articles/473266

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