Journals / Bursa Devlet Hastanesi Bülteni / 1998 / Cilt: 14 - Sayı: 2

Evaluation of the phagocytosis and intracellular killing function of polymorphonuclear leukocytes to trichosporon beigelii

Trichosporon beigelii'ye karşı polimorfonüveli lökositlerin fagositoz ve hücre içi öldürme fonksiyonlarının değerlendirilmesi

Pages
139–141
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As a result; we find out that phagocytic function of the PNL of the patient was better than the healthy control against C albicans strains isolates from faeces and vagen flora, but intracellular killing function was diminished significantly.

📌 3 Key Takeaways

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Objective & Hypothesis:There isn 't any knowledge about Trichosporon beigelii which is known as opportunistic pathogen.
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Key Findings & Data:In this investigation, we searched the killing function of polymorphonuclear leukocytes (PNL) to T beigelii that isolated in urine specimens of the patient three different times who taken chemotherapy for breast carcinoma.
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Conclusion & Impact:As a result; we find out that phagocytic function of the PNL of the patient was better than the healthy control against C albicans strains isolates from faeces and vagen flora, but intracellular killing function was diminished significantly.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

SUMMARY. There isn 't any knowledge about Trichosporon beigelii which is known as opportunistic pathogen. In this investigation, we searched the killing function of polymorphonuclear leukocytes (PNL) to T beigelii that isolated in urine specimens of the patient three different times who taken chemotherapy for breast carcinoma. It has matched with the healthy volunteer's PNL function. The same procedures have undertaken again for Candida albicans in the patient's faeces and vaginal flora and evaluated PNL response for both different yeasts. As a result; we find out that phagocytic function of the PNL of the patient was better than the healthy control against C albicans strains isolates from faeces and vagen flora, but intracellular killing function was diminished significantly.

Özet

ÖZET. Fırsatçı patojen olarak bilinen Trichosporon beigelii'ye karşı konak defans mekanizmaları hakkında çok az bilgi vardır. Bu çalışmada meme karsinomu nedeniyle kemoterapi alan hastanın idrarından mükerrer olarak izole edilen T beigelii'ye karşı konakpolimorfonüveli lökositlerinin (PNL) fagositoz ve hücre içi öldürme fonksiyonları araştırıldı. Sağlıklı gönüllülerin PNL fonksiyonları ile karşılaştırıldı. Aynı testler hastanın dışkı ve vagen floralarında bulunan Candida albicans ile tekrarlanarak farklı tipteki mantarlara karşı PNL yanıtları değerlendirildi. Sonuç olarak hastanın PNL'nin T beigelii'yi fagositozu; vagen ve rektum florasında kolonize olan C albicans suşlarına ve sağlıklı kontrole göre arttığı fakat hücre içinde öldürülmesinin anlamlı olarak azalmış olduğu saptandı (p < 0.001).

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Cite This Article

KARADENİZLİ, A. Y., KATIRCIOĞLU, İ., GÜLENÇ, S., BİNGÖL, R. (2022). Evaluation of the phagocytosis and intracellular killing function of polymorphonuclear leukocytes to trichosporon beigelii. Bursa Devlet Hastanesi Bülteni, Cilt: 14 - Sayı: 2, 139–141. https://ajindex.com/articles/469458