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Journals / Bezmiâlem Science / 2020 / Cilt: 8 - Sayı: 2

The Relationship of Hemogram and InflammatoryBiomarkers to Lenght of Stay in Hospital and Clinical Coursein Patients with COVID-19

COVİD-19 Olgularında Hemogram ve Enflamasyon Biyobelirteçlerinin Hastane Yatış Süresi ve Klinik Seyirle Ilişkisi

Banu BÜYÜKAYDIN
Pages
7–14
Publication Date
2022-10-12
DOI
—
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There was a positive correlation between NLR and PLR (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: It was aimed to research the relationship between neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), inflammatory markers and lenght of stay in hospital (LOS) with clinical results in hospitalized patients with Coronavirus disease-2019 (COVID-19).Methods: Total leukocyte, neutrophil, lymphocyte and platelet counts (/mm3), hemoglobin (g/dL), mean platelet volume, C-reactive protein (CRP) (mg/L), ferritin (ng/mL), lactate dehydrogenase (LDH) (U/L) creatine kinase (U/L), D-dimer (ng/mL), troponin-I (pg/mL), alanine aminotransferase (U/L), aspartate aminotransferase (U/L) and serum creatinine (mg/dL) measurements were recorded.
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Key Findings & Data:Applied treatments, intensive care unit requirement, and mortality rates were determined.
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Conclusion & Impact:There was a positive correlation between NLR and PLR (p
🔬Design:Research Article
📍Scope:2019 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: It was aimed to research the relationship between neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), inflammatory markers and lenght of stay in hospital (LOS) with clinical results in hospitalized patients with Coronavirus disease-2019 (COVID-19).Methods: Total leukocyte, neutrophil, lymphocyte and platelet counts (/mm3), hemoglobin (g/dL), mean platelet volume, C-reactive protein (CRP) (mg/L), ferritin (ng/mL), lactate dehydrogenase (LDH) (U/L) creatine kinase (U/L), D-dimer (ng/mL), troponin-I (pg/mL), alanine aminotransferase (U/L), aspartate aminotransferase (U/L) and serum creatinine (mg/dL) measurements were recorded. NLR and PLR were calculated. Applied treatments, intensive care unit requirement, and mortality rates were determined. For LOS and mortality, the sensitivity of biochemical parameters was evaluated.Results: One hundred seventy-one patients (87 females, 84 males) were evaluated. The mean age was 57.9±14.6 years, and the mean LOS was 8.83±6.4 days. There was a positive correlation between NLR and PLR (p

Özet

Amaç: Hospitalize Coronavirüs hastalığı-2019 (COVİD-19)olgularında nötrofil-lenfosit oranı (NLR), platelet-lenfosit oranı(PLR) ve enflamatuvar göstergelerin hastane yatış süresi (HYS) veklinik seyirle olan ilişkisini araştırmaktır. Yöntemler: Çalışmaya dahil edilen olguların total lökosit, nötrofil,lenfosit ve trombosit sayıları (/mm3 ), hemoglobin düzeyi (g/dL),ortalama trombosit hacmi, C-reaktif protein (CRP) (mg/L), ferritin(ng/mL), laktat dehidrogenaz (LDH) (U/L), kreatin kinaz (U/L),D-dimer (ng/mL), troponin-I (pg/mL), alanin aminotransferaz(U/L), aspartat aminotransferaz (U/L) ve serum kreatinin (mg/ dL) sonuçları kaydedildi. NLR ve PLR hesaplandı. Uygulanmışolan antiviral tedaviler kaydedildi. Yoğun bakım ünitesi takibi vemortalite oranları belirlendi. Biyokimyasal parametrelerin kendiaralarındaki korelasyon analizleri yapıldı ve parametrelerin HYS vemortalite öngörüsü için duyarlılıkları analiz edildi. Bulgular: Toplam 171 hastanın (87 kadın, 84 erkek) verilerideğerlendirildi. Ortalama yaş 57,9±14,6 yıl, ortalama HYS 8,83±6,4gündü. NLR ile PLR pozitif yönde koreleydi (p

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Cite This Article

BÜYÜKAYDIN, B. (2022). The Relationship of Hemogram and InflammatoryBiomarkers to Lenght of Stay in Hospital and Clinical Coursein Patients with COVID-19. Bezmiâlem Science, Cilt: 8 - Sayı: 2, 7–14. https://ajindex.com/articles/464074

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