Journals / Bezmiâlem Science / 2021 / Cilt: 9 - Sayı: 3

Food Allergy in Children

Çocuklarda Besin Alerjisi

Pages
373–379
Publication Date
2022-10-12
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Thus, this study will shed lighton identifying new immunotherapeutic approaches to allergens.

📌 3 Key Takeaways

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Objective & Hypothesis:Food allergy, which is defined as an inverse immune responseto food proteins, appears to increase gradually in children asa result of studies.
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Key Findings & Data:It affects 6% of children and 3-4% of adults.The role of breast milk in preventing the development of allergiesin children is controversial.
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Conclusion & Impact:Thus, this study will shed lighton identifying new immunotherapeutic approaches to allergens.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Food allergy, which is defined as an inverse immune responseto food proteins, appears to increase gradually in children asa result of studies. It affects 6% of children and 3-4% of adults.The role of breast milk in preventing the development of allergiesin children is controversial. Allergic reactions caused by foodin children cause many symptoms and disorders affecting thegastrointestinal tract, respiratory tract and skin. These symptomsoccur by immunoglobulin (Ig)E-mediated or non-IgE-mediatedmechanisms. The cornerstone of food allergy treatment is removingfoods from the diet by strict elimination method. Along with thegenetic tendency, environmental factors can eliminate oral toleranceand cause food allergy. Disease results are affected by the immunesystem and trigger allergen properties. Foods that cause food allergiesare a few, mainly milk, eggs, peanuts, nuts, fish and shellfish. Inthis review, the level of knowledge about the pathogenesis of theimmunological response about most allergens, which are specialsubstances in the protein structure found in foods, has beendiscussed with studies conducted. Thus, this study will shed lighton identifying new immunotherapeutic approaches to allergens.

Özet

Besin proteinlerine ters bir immün yanıt olarak tanımlanan besin alerjisi, yapılan çalışmaların sonucunda çocuklarda giderek arttığı görülmektedir. Çocukların %6’sını ve yetişkinlerin %3- 4’ünü etkilemektedir. Anne sütünün çocuklarda alerji gelişimini önlemesindeki rolü ise tartışmalıdır. Çocuklarda görülen besin kaynaklı alerjik reaksiyonlar gastrointestinal sistemi, solunum yollarını ve deriyi etkileyen birçok semptom ve bozukluklara yol açmaktadır. Bu semptomlar immünoglobulin (Ig)E aracılı ve IgE aracılı olmayan mekanizmalarla gerçekleşmektedir. Besin alerjisi tedavisinin temel taşı, besinlerin diyetten katı eliminasyon yöntemiyle çıkarılmasıdır. Genetik eğilim ile birlikte çevresel faktörler de oral toleransı ortadan kaldırarak besin alerjisi oluşmasına neden olabilmektedir. Hastalık sonuçları, bağışıklık sistemi ve tetikleyici alerjen özelliklerinden etkilenmektedir. Besin alerjilerine yol açan besinler az sayıda olup başlıcalarını süt, yumurta, yerfıstığı, fındık, balık ve kabuklu deniz ürünleri oluşturmaktadır. Bu derlemede besinlerde bulunan protein yapısındaki özel maddeler olan alerjenlerin çoğu hakkında immünolojik yanıtın patogenezi konusunda bilgi düzeyi yapılan çalışmalarla tartışılmıştır. Böylece, bu çalışma ile alerjenlere karşı yeni immünoterapötik yaklaşımların belirlenmesine ışık tutulacaktır.

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Cite This Article

BAYIR, A. G., CAN, B., EKİNGEN, Ş. (2022). Food Allergy in Children. Bezmiâlem Science, Cilt: 9 - Sayı: 3, 373–379. https://ajindex.com/articles/463981

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References (19)

  1. Longo G, Berti I, Burks AW, Krauss B, Barbi E. IgE-mediated food allergy in children. Lancet 2013;382:1656-64
  2. Sicherer SH, Sampson HA
  3. Food allergy. J Allergy Clin Immunol 2006;117:470-5
  4. Pavić I, Kolaček S. Growth of Children with Food Allergy. Horm Res Paediatr 2017;88:91-100
  5. Sicherer SH, Sampson HA. Food allergy. J Allergy Clin Immunol 2010;125:116-25
  6. Tordesillas L, Berin MC, Sampson HA. Immunology of Food Allergy. Immunity 2017;47:32-50
  7. Devdas JM, Mckie C, Fox AT, Ratageri VH. Food Allergy in Children: An Overview. Indian J Pediatr 2018;85:369-74
  8. Ebisawa M, Ito K, Fujisawa T; Committee for Japanese Pediatric Guideline for Food Allergy, The Japanese Society of Pediatric Allergy and Clinical Immunology, The Japanese Society of Allergology. Japanese guidelines for food allergy 2017. Allergol Int 2017;66:248- 64
  9. Turnbull JL, Adams HN, Gorard DA. Review article: the diagnosis and management of food allergy and food intolerances. Aliment Pharmacol Ther 2015;41:3-25
  10. Moore LE, Stewart PH, deShazo RD. Food Allergy: What We Know Now. Am J Med Sci 2017;353:353-66
  11. Karakılıç M, Suna S, Tamer CE, Çopur ÖU. Gıda Alerjisi Reaksiyonları. Uludağ Üniversitesi Ziraat Fakültesi Dergisi 2014;28:73-82
  12. Kraneveld AD, Sagar S, Garssen J, Folkerts G. The two faces of mast cells in food allergy and allergic asthma: the possible concept of Yin Yang. Biochim Biophys Acta 2012;1822:93-9
  13. Geha RS, Jabara HH, Brodeur SR. The regulation of immunoglobulin E class-switch recombination. Nat Rev Immunol 2003;3:721-32
  14. Burks AW, Tang M, Sicherer S, Muraro A, Eigenmann PA, Ebisawa M, et al. ICON: food allergy. J Allergy Clin Immunol 2012;129:906- 20
  15. Harish Babu BN, Wilfred A, Venkatesh YP. Emerging food allergens: Identification of polyphenol oxidase as an important allergen in eggplant (Solanum melongena L.). Immunobiology 2017;222:155- 63
  16. Hoseini-Alfatemi SM, Bayry J, Sharifi-Rad J. IgE response to two new allergen proteins of Solanum melongena L. (eggplant). Immunol Lett 2015;168:268-70
  17. Ando H, Movérare R, Kondo Y, Tsuge I, Tanaka A, Borres MP, et al. Utility of ovomucoid-specific IgE concentrations in predicting symptomatic egg allergy. J Allergy Clin Immunol 2008;122:583-8
  18. Boyano-Martínez T, García-Ara C, Díaz-Pena JM, Martín-Esteban M. Prediction of tolerance on the basis of quantification of egg whitespecific IgE antibodies in children with egg allergy. J Allergy Clin Immunol 2002;110:304-9
  19. Savage JH, Mat