Journals / Balkan Medical Journal / 2013 / Cilt: 30 - Sayı: 1

Acute effects of moderate and strenuous running on trace element distribution in the brain, liver, and spleen of trained rats

Pages
105–110
Publication Date
2022-10-11
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

From this study, it can be inferred that sportsmen should aware trace element disturbances among the body parts or depletion of some trace elements after single bout of chronic strenuous running exercise.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Trace elements such as manganese (Mn), cobalt (Co) and chromium (Cr) play key roles in metabolic reactions and are important in many physi- ological enzymatic processes.
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Key Findings & Data:In this study, we aimed to investigate the acute effects of moderate and strenuous running (treadmill) exercise on the levels of Mn, Co and Cr in the brain, liver, and spleen of trained rats.
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Conclusion & Impact:From this study, it can be inferred that sportsmen should aware trace element disturbances among the body parts or depletion of some trace elements after single bout of chronic strenuous running exercise.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Trace elements such as manganese (Mn), cobalt (Co) and chromium (Cr) play key roles in metabolic reactions and are important in many physi- ological enzymatic processes. In this study, we aimed to investigate the acute effects of moderate and strenuous running (treadmill) exercise on the levels of Mn, Co and Cr in the brain, liver, and spleen of trained rats. Study Design: Animal experiment. Material and Methods: Twenty-one Wistar-Albino adult male rats were used in the study. Rats were grouped as control group (no mandated exercise; n=8), moderate exercise group (30 min exercise duration; n=7), and strenuous exercise group (60 min exercise duration; n=6). The levels of Mn, Co, and Cr in the frontal lobe, temporal lobe, brain stem, liver, and spleen were determined by atomic absorption spectrophotometer. Results: Cr levels in liver of rats increased in parallel to the time course of running supporting the exercise training effect on the action of insulin. Compared to the control group, the level of Co significantly decreased in the brain stem of rats in the moderate exercise group (p=0.009) and in the frontal lobe of rats in the strenuous exercise group (p=0.004). In the strenuous exercise group, an examination of the brain stem revealed that the level of Mn significantly decreased (p=0.001), and levels of Co and Cr were apparently depleted to the extent that these elements were no longer detectable. Conclusion: A notable finding is that during or after single bout strenuous exercise, levels of Co decreased in the spleen and particularly decreased in the brain stem of regularly trained rats. From this study, it can be inferred that sportsmen should aware trace element disturbances among the body parts or depletion of some trace elements after single bout of chronic strenuous running exercise.

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Cite This Article

DÜZOVA, H., KARAKOÇ, Y., EMRE, M. H., ERGEN, K., İNCE, H. (2022). Acute effects of moderate and strenuous running on trace element distribution in the brain, liver, and spleen of trained rats. Balkan Medical Journal, Cilt: 30 - Sayı: 1, 105–110. https://ajindex.com/articles/461528

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References (13)

  1. Kozma M, Ferke A. Trace element localization and changes in zinc and copper concentrations during postnatal development of the rat CNS. Acta Histochem 1979
  2. [CrossRef] 2.Rath FW, Grahl R, Felicetti D. The histochemical behaviour of zinc-activated tartrate-resistant phosphatase (ZnTP) in early stag- es of experimental tumors in the rat trigeminal nerve. Exp Pathol (Jena) 1980
  3. [CrossRef] 3.Usdin TB, Creese I, Snyder SH. Regulation by cations of [3H] spiroperidol binding associated with dopamine receptors of rat brain. J Neurochem 1980
  4. [CrossRef] 4.Leong SF, Lai JC, Lim L, Clark JB. Energy-metabolizing enzymes in brain regions of adult and aging rats. J Neurochem 1981
  5. [CrossRef] 5.Lai JC, Leung TK, Lim L. Brain regional distribution of glutamic acid decarboxylase, choline acetyltransferase, and acetylcho- linesterase in the rat:effects of chronic manganese chloride administration after two years. J Neurochem 1981
  6. [CrossRef] 6.Kemp K, Danscher G. Multi-element analysis of the rat hippo- campus by proton induced X-ray emission spectroscopy (phos- phorus, sulphur, chlorine, potassium, calcium, iron, zinc, copper, lead, bromine, andrubidium). Histochemistry 1976
  7. [CrossRef] 7. Rajan KS, Colburn RW, Davis JM. Distribution of metal ions in the subcellular fractions of several rat brain areas. Life Sci 1976
  8. [CrossRef] 8. Chan AW, Minski MJ, Lai JC. An application of neutron activa- tion analysis to small biological samples:simultaneous determina- tion of thirty elements in rat brain regions. J Neurosci Methods 1983
  9. [CrossRef] 9. Takahashi S, Takahashi I, Sato H, Kubota Y, Yoshida S, Muramat- su Y. Age-related changes in the concentrations of major and trace elements in the brain of rats and mice. Biol Trace Elem Res 2001
  10. [CrossRef] 10. Anderson RA. Recent advances in the clinical and biochemical effects of chromium deficiency. In:Prasad AS, ed. Essential and Toxic Trace Elements in Human Health and Disease:An Update. New York:Wiley Liss
  11. Anderson RA, Polansky MM, Bryden NA, Roginski EE, Patterson KY, Reamer DC. Effect of exercise (running) on serum glucose, in- sulin, glucagon, and chromium excretion. Diabetes 1992
  12. [CrossRef] 12. Vallerand AL, Cuerrier JP, Shapcott D, Vallerand RJ, Gardiner PF. Influence of exercise training on tissue chromium concentrations in the rat. Am J Clin Nutr 1984
  13. Kobla HV, Volpe SV. Chromium, exercise, a