Journals / Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi / 2014 / Cilt: 24 - Sayı: 2

EVALUATION OF INFLAMMATORY CYTOKINE AND PLASMA TITANIUM LEVELS IN DENTAL IMPLANT TREATED PATIENTS

DENTAL İMPLANTLARLA TEDAVİ EDİLEN HASTALARIN INFLAMATUAR SİTOKİN VE PLAZMA TİTANYUM SEVİYELERİNİN DEĞERLENDİRMESİ

Pages
199–205
Publication Date
2022-10-10
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

A comparison of pre- and post-dental implant applications in all study groups showed no differences for levels of serum Ti, IL-6, IL10, or TNF-alpha (p>0.05) except for IL-1 beta (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: This study aims to evaluate the corrosion properties of Titanium (Ti) dental implants in blood and also, measure the inflamatory cytocine secretion to affect of physiological corrosion on Ti implants.
📊
Key Findings & Data:Group 1 was treated with the Zimmer Tapered ScrewVent implant system which has a Microtextured Ti surface.
💡
Conclusion & Impact:A comparison of pre- and post-dental implant applications in all study groups showed no differences for levels of serum Ti, IL-6, IL10, or TNF-alpha (p>0.05) except for IL-1 beta (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: This study aims to evaluate the corrosion properties of Titanium (Ti) dental implants in blood and also, measure the inflamatory cytocine secretion to affect of physiological corrosion on Ti implants. Method: Forty patients were divided to two groups. Group 1 was treated with the Zimmer Tapered ScrewVent implant system which has a Microtextured Ti surface. Group 2 was treated with the Implant Direct ScrewPlant implant system which has a Hydroxy Apatite surface. All implants were inserted in posterior mandibular region. Prior to implantation and 4 months after the surgery, peripheral blood samples were taken and analyzed. Results: The Ti levels of every member in the study group was increased, but not to a statistically significant degree (p>0.05). A comparison of pre- and post-dental implant applications in all study groups showed no differences for levels of serum Ti, IL-6, IL10, or TNF-alpha (p>0.05) except for IL-1 beta (p

Özet

Amaç: Bu çalışmada kanda Titanyum (Ti) dental implantların korozyon ürünlerinin ve de fizyolojik korozyonu etkileyen inflamatuar sitokin sekresyonunun Ti implantlar üzerine etkisinin değerlendirilmesi amaçlanmıştır. Metod: Kırk hasta iki gruba ayrıldı. Group 1 Microtextured Ti yüzeye sahip Zimmer Tapered ScrewVent implantlar ile tedavi edildi. Group 2 Hidroksi Apatit yüzeye sahip Implant Direct ScrewPlant implant sistemi ile tedavi edildi. Bütün implantlar mandibular posterior bölgeye yerleştirildi. İmplantasyon öncesi ve cerrahiden 4 ay sonar periferal kan örnekleri alındı ve analiz edildi. Bulgular: Çalışma gruplarının hepsinde istatiksel olarak anlamlı olmasa da artmıştır (p>0.05). Bütün gruplar implant uygulaması öncesi ve sonrası serum Ti seviyeleri karşılaştırıldığında serum IL-1 beta (p0.05) seviyelerinde artma saptanmamıştır. Sonuç: Serum Ti seviyesi ile implant uygulanması arasında bir ilişki saptanmamıştır.

🔖

Cite This Article

KÜÇÜKSEZER, U., AK, G., KILIÇ, S., KAZANCIOĞLU, H. O., DENIZ, G. (2022). EVALUATION OF INFLAMMATORY CYTOKINE AND PLASMA TITANIUM LEVELS IN DENTAL IMPLANT TREATED PATIENTS. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi, Cilt: 24 - Sayı: 2, 199–205. https://ajindex.com/articles/452227

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Kazancioglu HO, Cakir O, Koyuncuoglu G, Ciftci A, Ak G. Oral Findings and Health Status among Turkish Geriatric Patients with or without Dementia. Int J Gerontol. 2012;
  2. McGarry S, Morgan SJ, Grosskreuz RM, Williams AE, Smith WR. Serum titanium levels in individuals undergoing intramedullary femoral nailing with titanium implant. J Trauma 2008;64:430-3
  3. Chaturvedi TP. An overview of the corrosion aspect of dental implants. Indian J Dent Res 2009;20:91-8
  4. Bianco PD, Ducheyne P, Cuckler JM. Titanium serum and urine levels in rabbits with a titanium implant in the absence of wear. Biomaterials 1996;17:1937-42
  5. Williams DF, Adams D. A histochemical method for the determination of titanium in tissues surrounding implants. J Clin Pathol 1976;29:657-61
  6. Williams D, Adams D, Mort E. A histochemical method for the detection of metals in tissues, with reference to the use of surgical implants. Microsc Acta 1978;81:1-7
  7. Frisken KW, Dandie GW, Lugowski S, Jordan G. A study of titanium release into body organs following the insertion of single threaded screw implants into the mandibles of sheep. Aust Dent J 2002;47:214-7
  8. Takamura K, Hayashi K, Ishinishi N, Yamada T, Sugioka Y. Evaluation of carcinogenicity and chronic toxicity associated with orthopedic implants in mice. J Biomed Mat Res 1994;28:583-9
  9. Rae T. The biological response to titanium and titanium-aluminum-vanadium alloy particles. I. Tissue culture studies. Biomaterials 1986;7:30- 6
  10. Sedarat C, Harmand MF, Naji A, Nowzari H. In vitro kinetic evaluation of titanium alloy biodegradation. J Periodontal Res 2001;36:269- 74
  11. Meyer U, Bühner M, Büchter A, Kruse-Löster B, Stamm T, Wiesmann HP. Fast element mapping of titanium wear around implants of different surface structures. Clin Oral Implants Res 2006;17:206-11
  12. Weingart D, Steinemann S, Schili W, Strub JR, Hellerich U, Assenmacher J, et al. Titanium deposition in regional lymph nodes after insertion of titanium screw implants in maxillofacial region. Int J Oral Maxillofac Surg 1994;23:450-2
  13. Morais LS, Serra GG, Palermo EFA, Andrade LR, Müller CA, Meyers MA, et al. Systemic levels of metallic ions released from orthodontic miniimplants. Am J Orthod Dentofacial Orthop 2009;135:522-9
  14. Sarmiento-González A, Marchante-Gayón JM, Tejerina-Lobo JM, Paz-Jiménez J, Sanz-Medel A. ICP-MS multielemental determination of metals potentially released from dental implants and articul