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Journals / Adıyaman Üniversitesi Fen Bilimleri Dergisi / 2021 / Cilt: 11 - Sayı: 2

Evaluation of radiation attenuation properties of some cancer drugs

İlyas ÇAĞLAR
Gülçin BİLGİCİ CENGİZ (EKER)
Pages
503–522
Publication Date
2021-12-31
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The data obtained from this study are expected to be useful in the fields of radiation biology, radiation dosimetry and radiotherapy.

📌 3 Key Takeaways

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Objective & Hypothesis:The present study was conducted to estimate the radiation attenuation parameters of six different antineoplastic drugs used in the cure of cancer diseases.
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Key Findings & Data:The effective atomic number and electron density of anastrozole, epirubicin, gemcitabine, ifosfamide, methotrexate and paclitaxel were computed theoretically in the energy region of 1keV to 100 GeV.
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Conclusion & Impact:The data obtained from this study are expected to be useful in the fields of radiation biology, radiation dosimetry and radiotherapy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Cancer drugs · Radiation · Effective atomic number

Abstract

The present study was conducted to estimate the radiation attenuation parameters of six different antineoplastic drugs used in the cure of cancer diseases. The effective atomic number and electron density of anastrozole, epirubicin, gemcitabine, ifosfamide, methotrexate and paclitaxel were computed theoretically in the energy region of 1keV to 100 GeV. The energy absorption buildup factors (EABF) and exposure buildup factors (EBF) for these chemotherapy drugs were also examined by applying GP-fitting method. The variation of EABF and EBF values with photon energy and penetration depth were presented graphically and discussed. The results obtain from this study pointed out that buildup factors rely on the chemical combination of the drugs, incident photon energy and penetration thickness. It was observed that ifosfamide had a significantly better radiation absorption effect compared to other drugs. The data obtained from this study are expected to be useful in the fields of radiation biology, radiation dosimetry and radiotherapy.

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Cite This Article

ÇAĞLAR, İ., (EKER), G. B. C. (2021). Evaluation of radiation attenuation properties of some cancer drugs. Adıyaman Üniversitesi Fen Bilimleri Dergisi, Cilt: 11 - Sayı: 2, 503–522. https://ajindex.com/articles/451014

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