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Journals / Archives of Rheumatology / 2017 / Cilt: 32 - Sayı: 3

Primary Sjögren's Syndrome First Presenting as Hypokalemic Quadriparesis

Rolando MARTÍNEZ-GRANADOS
Pages
257–259
Publication Date
2022-10-11
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Our patient was treated with potassium citrate and later discharged on this treatment.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Hypokalemic paralysis and respiratory failure associated with distal renal tubular acidosis as first clinical manifestation of primary Sjögren's syndrome has been reported a few times.
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Key Findings & Data:In this article, we describe the case of a previously healthy 38-year-old female patient who presented to the emergency department with a three-day history of dyspnea at rest and rapidly progressive generalized muscular weakness.
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Conclusion & Impact:Our patient was treated with potassium citrate and later discharged on this treatment.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Hypokalemic paralysis and respiratory failure associated with distal renal tubular acidosis as first clinical manifestation of primary Sjögren's syndrome has been reported a few times. In this article, we describe the case of a previously healthy 38-year-old female patient who presented to the emergency department with a three-day history of dyspnea at rest and rapidly progressive generalized muscular weakness. Her initial work-up revealed an uncompensated hyperchloremic metabolic acidosis and severe hypokalemia. Additionally, urine pH of 8.0 and other findings consistent with distal renal tubular acidosis were found. We excluded the most common causes of distal renal tubular acidosis and finally established the diagnosis of primary Sjögren's syndrome. Our patient was treated with potassium citrate and later discharged on this treatment.

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Cite This Article

MARTÍNEZ-GRANADOS, R. (2022). Primary Sjögren's Syndrome First Presenting as Hypokalemic Quadriparesis. Archives of Rheumatology, Cilt: 32 - Sayı: 3, 257–259. https://ajindex.com/articles/448034

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References (16)

  1. Jandhyala SN, Madireddi J, Belle J, Rau NR, Shetty R. Hypokalaemic Periodic Paralysis- A Prospective Study of the Underlying Etiologies. J Clin Diagn Res 2015;9:17-9
  2. Ahlawat SK, Sachdev A. Hypokalaemic paralysis. Postgrad Med J 1999;75:193-7
  3. Rodríguez Soriano J. Renal tubular acidosis: the clinical entity. J Am Soc Nephrol 2002;13:2160-70
  4. Evans R, Zdebik A, Ciurtin C, Walsh SB. Renal involvement in primary Sjögren's syndrome. Rheumatology (Oxford) 2015;54:1541-8
  5. Duffles Amarante GB, Zotin MC, Rocha E, Delgado AG, Leite M Jr, Gomes CP. Renal tubular dysfunction in patients with primary Sjögren syndrome. Clin Nephrol 2014;81:185-91
  6. Fraer M. A mask and many faces: hypokalemic periodic paralysis. South Med J 2008;101:887
  7. Bagga A, Sinha A. Evaluation of renal tubular acidosis. Indian J Pediatr 2007;74:679-86
  8. Sengul E, Bunul F, Yazici A, Sengul A, Dindar S, Halhalli GS, et al. An unusual ınitial presentation of Sjögren's syndrome: severe hypokalemic paralysis secondary to distal renal tubular acidosis. Eurasian J Med 2013;45:218-21
  9. Yılmaz H, Kaya M, Özbek M, ÜUreten K, Safa Yıldırım _____. Hypokalemic periodic paralysis in Sjogren's syndrome secondary to distal renal tubular acidosis. Rheumatol Int 2013;33:1879-82
  10. Shearn MA, Tu WH. Nephrogenic diabetic insipidus and other defects of renal tubular function in sjoergren's syndrome. Am J Med 1965;39:312-8
  11. Both T, Zietse R, Hoorn EJ, van Hagen PM, Dalm VA, van Laar JA, et al. Everything you need to know about distal renal tubular acidosis in autoimmune disease. Rheumatol Int 2014;34:1037-45
  12. Cohen EP, Bastani B, Cohen MR, Kolner S, Hemken P, Gluck SL. Absence of H(+)-ATPase in cortical collecting tubules of a patient with Sjogren's syndrome and distal renal tubular acidosis. J Am Soc Nephrol 1992;3:264-71
  13. Takemoto F, Hoshino J, Sawa N, Tamura Y, Tagami T, Yokota M, et al. Autoantibodies against carbonic anhydrase II are increased in renal tubular acidosis associated with Sjogren syndrome. Am J Med 2005;118:181-4
  14. Cornec D, Jamin C, Pers JO. Sjögren's syndrome: where do we stand, and where shall we go? J Autoimmun 2014;51:109-14
  15. Both T, Hoorn EJ, Zietse R, van Laar JA, Dalm VA, Brkic Z, et al. Prevalence of distal renal tubular acidosis in primary Sjögren's syndrome. Rheumatology (Oxford) 2015;54:933-9
  16. Bossini N, Savoldi S, Franceschini F, Mombelloni S, Baronio M, Cavazzana I, et al. Clinical and morphological features of kidney involvement in primar