Journals / Archives of Basic and Clinical Research / 2021 / Cilt: 3 - Sayı: 2

General View on the COVID-19 Infection Factor and Diagnosis

COVID-19 Enfeksiyon Etkenine ve Tanı Konulmasına Genel Bakış

Pages
70–75
Publication Date
2022-10-12
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this study, it is aimed to give information about the structure of SARS- CoV-2 virus causing the pandemic today and the tests used to di- agnose SARS-CoV-2.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The coronavirus family is a large family that can be determined in humans or animals.
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Key Findings & Data:World Health Organization, China Country Office, reported cases of pneumonia of unknown etiology in Wuhan, Hubei Province, on December 31, 2019.
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Conclusion & Impact:In this study, it is aimed to give information about the structure of SARS- CoV-2 virus causing the pandemic today and the tests used to di- agnose SARS-CoV-2.
🔬Design:Research Article
📍Scope:2019 Verileri
⚙️Variables:Domain Parameters

Abstract

The coronavirus family is a large family that can be determined in humans or animals. They may cause both mild common colds in humans and severe infections such as Middle East Respirato- ry Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS). Coronavirus subtypes determined in humans are easily transmitted from person to person and usually cause mild colds. Many coronavirus subtypes detected in animals can cause se- vere illnesses in humans by transmitting from animals to humans. World Health Organization, China Country Office, reported cases of pneumonia of unknown etiology in Wuhan, Hubei Province, on December 31, 2019. On January 7, 2020, the agent causing pneu- monia was identified as the new coronavirus (2019-nCoV) which has not been detected in humans before and because of its close similarity to SARS-CoV, SARS-CoV-2 and the infection it caused has been named as Acute Viral Respiratory Infection (COVID-19). The World Health Organization declared the COVID-19 infection caused by SARS-CoV-2, the 7th coronavirus known to infect hu- mans, as a pandemic on March 11, 2020 because of its prevalance and severity. Today, the pandemic still continues and the number of deaths and cases is increasing day by day. The agent is needed to diagnose accurately and quickly to control the pandemic and to prevent its spread. The standard and reliable method for diag- nosing the SARS-CoV-2 agent is the detection of viral genes by real-time reverse transcription (qRT) polymerase chain reaction (PCR), which is the nucleic acid amplification test (NAAT). In this study, it is aimed to give information about the structure of SARS- CoV-2 virus causing the pandemic today and the tests used to di- agnose SARS-CoV-2.

Özet

Koronavirus ailesi, insanlarda veya hayvanlarda tespit edilebi- len geniş bir ailedir. İnsanlarda hafif soğuk algınlığı tablolarından, Orta Doğu Solunum Sendromu (MERS) ve Ağır Akut Solunum Sendromu (SARS) gibi ciddi enfeksiyon tablolarına kadar değişen hastalıklara neden olabilmektedirler. İnsanlarda tespit edilen ko- ronavirus alt tipleri, insandan insana kolayca bulaşmakta ve genel- likle hafif soğuk algınlığına sebep olmaktadırlar. Hayvanlarda tes- pit edilen pek çok koronavirus alt tipleri ise hayvanlardan insanlara geçerek insanlarda ağır hastalık tablolarına sebep olabilmektedir- ler. Dünya Sağlık Örgütü, Çin Ülke Ofisi, 31 Aralık 2019’da, Hubei Eyaleti, Wuhan kentinde etiyolojisi bilinmeyen pnömoni vakaları bildirmiştir. 7 Ocak 2020 tarihinde, pnömoniye sebep olan etken, daha önce insanlarda tespit edilmemiş yeni koronavirus (2019- nCoV) olarak tanımlanmış ve SARS- CoV’ a yakın benzerliği sebebi ile SARS-CoV-2 ve sebep olduğu enfeksiyon Akut Viral Solunum Enfeksiyonu (COVID-19) olarak isimlendirilmiştir. Dünya Sağlık Örgütü, insanları enfekte ettiği bilinen 7. koronavirus olan SARS- CoV-2’ nin sebep olduğu COVID-19 enfeksiyonunu, yayılma hızı ve ciddiyeti sebebi ile 11 Mart 2020 tarihinde pandemi olarak ilan etmiştir. Günümüzde, pandemi hala devam etmekte ve her geçen gün ölüm ve vaka sayıları artmaktadır. Pandeminin kontrol altına alınabilmesi ve yayılmasının önlenebilmesi için etkenin doğru ve hızlı teşhis edilmesi gerekmektedir. SARS-CoV-2 etkenine tanı konulmasında kullanılan standart ve güvenilir yöntem, nükleik asit amplifikasyon testi (NAAT) olan gerçek zamanlı ters transkripsi- yon (qRT) polimeraz zincir reaksiyonu (PCR) ile viral genlerin tes- pit edilmesidir. Çalışmamızda, günümüzde pandemiye sebep olan SARS-CoV-2 virusunun yapısı ve teşhisinde kullanılan testler hak- kında bilgi verilmesi amaçlanmıştır.

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Cite This Article

YILMAZ, A. (2022). General View on the COVID-19 Infection Factor and Diagnosis. Archives of Basic and Clinical Research, Cilt: 3 - Sayı: 2, 70–75. https://ajindex.com/articles/447785

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