Journals / Archives of Basic and Clinical Research / 2021 / Cilt: 3 - Sayı: 1

A Case of Vogt Koyanagi Harada Syndrome Treated as aPseudotumor Cerebri

Psödotümör Serebri Gibi Tedavi Edilen Bir Vogt Koyanagi Harada Sendromu Olgusu

Pages
34–37
Publication Date
2022-10-12
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

After one month of the treatment, the bilateral disk edema was resolved and visual acuities were increased in both eyes.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A 24-year-old female patient presented with blurred vision, tinnitus, and headache in another clinic.
📊
Key Findings & Data:She was found to have bilateral optic disk edema and was initially investigated for increased intracranial pressure.
💡
Conclusion & Impact:After one month of the treatment, the bilateral disk edema was resolved and visual acuities were increased in both eyes.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A 24-year-old female patient presented with blurred vision, tinnitus, and headache in another clinic. She was found to have bilateral optic disk edema and was initially investigated for increased intracranial pressure. As cranial imaging and the neurological examination were found to be completely normal, pseudotumor cerebri was suspected as the cause and the appropriate treatment was initiated. Due to no clinical improvement after one month of treatment, she applied to our clinic. In fluorescein angiography, bilateral optic disk edema and leakage from the discs, as well as multifocal leaking points were detected. In optical coherence tomography, bilateral areas of serous retinal detachment and increased choroidal thickness were detected. Based on all these findings, the patient was diagnosed as having Vogt Koyanagi Harada syndrome and was treated with 1 gr of methylprednisolone intravenously for days and azathioprine 50 mg two times a day. After one month of the treatment, the bilateral disk edema was resolved and visual acuities were increased in both eyes.

Özet

Dış merkezde bulanık görme, kulak çınlaması ve baş ağrısı şikayeti ile başvuran 24 yaşında kadın hasta yapılan muayenesinde her iki gözde optik disk ödemi görülmesi üzerine kafa içi basınç artışı yönünden araştırılmış, kraniyel görüntüleme ve nöroloji konsültasyonunun normal olarak değerlendirilmesi üzerine psödotümör serebri tanısı konarak tedavi edilmiştir. Ancak bir ay sonra şikayetlerinin düzelmemesi nedeniyle kliniğimize başvurmuş, çekilen floresein anjiyografide bilateral disk ödemi ile diskten sızıntı ve multifokal noktasal sızıntı odakları görülmüştür. Optik koherens tomografide her iki gözde seröz retina dekolmanı alanları ve artmış koroid kalınlığının görülmesi üzerine, hastaya Vogt Koyanagi Harada sendromu tanısı konarak uygun tedavi başlandı. Üç gün intravenöz 1 gr pulse metilprednisolon ve azatiopurin 50mg 2x1 ile başlanan tedavisinin 1.ayında hastanın, her iki gözünde disk ödeminin gerilediği ve görme keskinliklerinin arttığı görüldü.

🔖

Cite This Article

ÖZDEMİR, K., BUDAKOĞLU, Ö., BERKER, N. (2022). A Case of Vogt Koyanagi Harada Syndrome Treated as aPseudotumor Cerebri. Archives of Basic and Clinical Research, Cilt: 3 - Sayı: 1, 34–37. https://ajindex.com/articles/447770

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (1)

  1. O’Keefe GA, Rao NA. Vogt-Koyanagi-Harada disease. Surv Ophthalmol 2017; 62: 1-25. [Crossref] 2. Wall M. Idiopathic intracranial hypertension (pseudotumor cerebri). Curr Neurol Neurosci Rep 2008; 8: 87-93. [Crossref] 3. Damico FM, Cunha-Neto E, Goldberg AC, Iwai LK, Marin ML, Hammer J, et al. T-Cell Recognition and Cytokine Profile Induced by Melanocyte Epitopes in Patients with HLA-DRB1*0405-Positive and -Negative Vogt-Koyanagi-Harada Uveitis. Invest Ophthalmol Vis Sci 2005; 46: 2465-71. [Crossref] 4. Damico FM, Kiss S, Young LH. Vogt-Koyanagi-Harada disease. Semin Ophthalmol 2005; 20: 183-90. [Crossref] 5. Rajendram R, Evans M, Rao NA. Vogt-Koyanagi-Harada disease. Int Ophthalmol Clin 2005; 45: 115-34. [Crossref] 6. Read RW, Holland GN, Rao NA, Tabbara KF, Ohno S, Arellanes-Garcia L, et al. Revised diagnostic criteria for Vogt-Koyanagi-Harada disease: report of an international committee on nomenclature. Am J Ophthalmol 2001; 131: 647-52. [Crossref] 7. Tugal-Tutkun I, Ozyazgan Y, Akova YA, Sullu Y, Akyol N, Soylu M, et al. The spectrum of Vogt-Koyanagi-Harada disease in Turkey: VKH in Turkey. Int Ophthalmol. 2007; 27: 117-23. [Crossref] 8. Nichani P, Christakis PG, Micieli JA. Headache and Bilateral Optic Disc Edema as the Initial Manifestation of Vogt-Koyanagi-Harada Disease. J Neuroophthalmol 2020 Feb 25. [Crossref] 9. Lai T, Chan R, Chan C, Lam D. Effects of the duration of initial oral corticosteroid treatment on the recurrence of inflammation in Vogt-Koyanagi-Harada disease. Eye (Lond) 2009; 23: 543-8. [Crossref] 10. Paredes I, Ahmed M, Foster C. Immunomodulatory therapy for Vogt-Koyanagi-Harada patients as first-line therapy. Ocul Immunol Inflamm 2006; 14: 87-90. [Crossref] 11. Read RW, Rechodouni A, Butani N, Johnston R, LaBree LD, Smith RE, et al. Complications and prognostic factors in Vogt-Koyanagi-Harada disease. Am J Ophthalmol 2001; 131: 599-606. [Crossref]