Journals / Annals of Medical Sciences / 2000 / Cilt: 9 - Sayı: 1

The effect of P-aminophenol on the GSH and MDA levels in liver and protective effect of GSH: P-aminophenol does not effect antioxidant enzymes

Pages
3–6
Publication Date
2022-10-10
DOI
—
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Results: The GSH levels in the PAP-given group decreased significantly when compared to the control group (p

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Objective & Hypothesis:Purpose: In this study, p-Aminophenol (PAP)-mediated oxidative stress and the role of reduced glutathione (GSH) were investigated in rat hepatic tissue.
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Key Findings & Data:Methods: PAP (200 mg/kg) was injected to one group of rats.
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Conclusion & Impact:Results: The GSH levels in the PAP-given group decreased significantly when compared to the control group (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: In this study, p-Aminophenol (PAP)-mediated oxidative stress and the role of reduced glutathione (GSH) were investigated in rat hepatic tissue. Methods: PAP (200 mg/kg) was injected to one group of rats. PAP plus reduced glutathione (GSH;300 mg/kg) were given to another group. After 96 h, the animals were killed and SOD, GPx, CAT, GSSGR, GSH and MDA measured in the hepatic tissues. Results: The GSH levels in the PAP-given group decreased significantly when compared to the control group (p

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Cite This Article

İNAL, M., KANBAK, G. (2022). The effect of P-aminophenol on the GSH and MDA levels in liver and protective effect of GSH: P-aminophenol does not effect antioxidant enzymes. Annals of Medical Sciences, Cilt: 9 - Sayı: 1, 3–6. https://ajindex.com/articles/447499

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