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Journals / Annals of Medical Research / 2019 / Cilt: 26 - Sayı: 4

Effects of prenatal exposure to extremely low frequency magnetic field on testicular tissues of male rats

Erkan ERDEM
Devrim SARIBAL
Pages
713–716
Publication Date
2022-10-12
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

No correlation was shown between MDA and GSH levels.Conclusion: According to the results of this study, ELF-MF exposure could impair oxidant-antioxidant function and might increase oxidative stress and lipid peroxidation in the testicular tissue.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Extremely low-frequency magnetic field (ELF-MF) is produced by a large variety of electronic devices in everyday use.
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Key Findings & Data:This study was therefore undertaken to examine the effects of ELF-MF on oxidative stress parameters in rat testicular tissue.Material and Methods: Twenty-five Sprague Dawley rats were exposed to 50 Hz 500μT ELF-MF 24 hours a day, starting from the prenatal period.
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Conclusion & Impact:No correlation was shown between MDA and GSH levels.Conclusion: According to the results of this study, ELF-MF exposure could impair oxidant-antioxidant function and might increase oxidative stress and lipid peroxidation in the testicular tissue.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: Extremely low-frequency magnetic field (ELF-MF) is produced by a large variety of electronic devices in everyday use. This study was therefore undertaken to examine the effects of ELF-MF on oxidative stress parameters in rat testicular tissue.Material and Methods: Twenty-five Sprague Dawley rats were exposed to 50 Hz 500μT ELF-MF 24 hours a day, starting from the prenatal period. The exposure continued for further 60 days following the birth. Testicular tissue samples were collected and analyzed. The levels of an oxidative stress marker MDA, and an antioxidant scavenger GSH were investigated.Results: Long-term exposure to ELF-MF increased MDA levels and decreased GSH levels significantly. No correlation was shown between MDA and GSH levels.Conclusion: According to the results of this study, ELF-MF exposure could impair oxidant-antioxidant function and might increase oxidative stress and lipid peroxidation in the testicular tissue.

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Cite This Article

ERDEM, E., SARIBAL, D. (2022). Effects of prenatal exposure to extremely low frequency magnetic field on testicular tissues of male rats. Annals of Medical Research, Cilt: 26 - Sayı: 4, 713–716. https://ajindex.com/articles/447289

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References (15)

  1. Sang-Kon L, Sungman P, Yoon-Won K. The effects of extremely low-frequency magnetic fields on reproductive function in rodents. Insights from Animal Reproduction, INTECH, 2016
  2. Seifirad S, Farzampour S, Nourbakhsh M, et al. Effects of extremely low frequency electromagnetic fields on paraoxonase serum activity and lipid peroxidation metabolites in rat. J Diabetes Metab Disord. 2014;13:85
  3. Non-Ionizing Radiation, Part 1: Static and extremely low-frequency (ELF) Electric and Magnetic Fields IARC Monographs on the evaluation of carcinogenic risks to humans, No
  4. IARC Working Group on the Evaluation of Carcinogenic Risk to Humans.https://www.ncbi.nlm.nih.gov/books/NBK390731/ access date 19.06.2002 4. Murphy MP. How mitochondria produce reactive oxygen species. Biochem J 2009;417:1-13
  5. Santini SJ, Cordone V, Falone S, et al. Role of mitochondria in the oxidative stress ınduced by electromagnetic fields: focus on reproductive systems. Oxid Med Cell Longev 2018;2018:5076271
  6. Buege JA, Aust STD. Microsomal lipid peroxidation. Methods Enzymol 1978;52:302-10
  7. Anderson ME. Determination of glutathione and glutathione disulfide in biological samples. Methods Enzymol 1985;113:548-55
  8. Lee SK, Park S, Gimm YM, et al. Extremely low frequency magnetic fields induce spermatogenic germ cell apoptosis: possible mechanism. BioMed Res Int 2014;567183
  9. Hong R, Liu Y, Yu YM, et al. Effects of extremely low frequency electromagnetic fields on male reproduction in mice. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2003;21:342-5
  10. Erdal N, Gurgul S, Tamer L, et al. Effects of long-term exposure of extremely low frequency magnetic field on oxidative/nitrosative stress in rat liver. J Radiat Res 2008;49:181-7
  11. Ayata A, Mollaoglu H, Yilmaz HR, et al. Oxidative stress-mediated skin damage in an experimental mobile phone model. J Dermatol 2004;31:878-83
  12. Lee BC, Johng HM, Lim JK, et al. Effects of extremely low frequency magnetic field on the antioxidant defense system in mouse brain: a chemiluminescence study. J Photochem Photobiol B 2004;73:43-8
  13. Akdag MZ, Dasdag S, Ulukaya E, et al. Effects of extremely low-frequency magnetic field on caspase activities and oxidative stress values in rat brain. Biol Trace Elem Res 2010;138:238-49
  14. Ayala A, Muñoz MF, Argüelles S. Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal. Oxidative Med Cellr Longev 2014;360438
  15. Grotto D, Maria LS, Va