Effects of tracheal intubation without muscle relaxants on postoperative recovery conditions in patients with obstructive sleep apnea: A double-blind randomized controlled study
Group R received 4 mcg/kg remifentanil and Group Ereceived 0.6 mg/kg rocuronium and then the patients’ intubation difficulty scale scores and their responses to train-of-four (TOF)nerve stimulation, and postoperative recovery were evaluated in both groups.Results: The median time to recovery of the TOF ratio to 0 following anesthetic induction was significantly higher in Group Rcompared to Group E (p
📌 3 Key Takeaways
🎯
Objective & Hypothesis:Aim: We aimed to compare intubation with and without neuromuscular blocking agents with regard to intubation success,hemodynamic parameters, and postoperative recovery in Obstructive sleep apnea patients.Materials and Methods: The study included 60 patients with a STOP-Bang (Snoring, Tiredness during daytime, Observed apnea,high blood Pressure, Body mass index, Age, Neck circumference, Gender) score of ≥3.
📊
Key Findings & Data:The patients were randomly divided into twogroups: (I) rocuronium group (Group E) and (II) remifentanil group (Group R).
💡
Conclusion & Impact:Group R received 4 mcg/kg remifentanil and Group Ereceived 0.6 mg/kg rocuronium and then the patients’ intubation difficulty scale scores and their responses to train-of-four (TOF)nerve stimulation, and postoperative recovery were evaluated in both groups.Results: The median time to recovery of the TOF ratio to 0 following anesthetic induction was significantly higher in Group Rcompared to Group E (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
Aim: We aimed to compare intubation with and without neuromuscular blocking agents with regard to intubation success,hemodynamic parameters, and postoperative recovery in Obstructive sleep apnea patients.Materials and Methods: The study included 60 patients with a STOP-Bang (Snoring, Tiredness during daytime, Observed apnea,high blood Pressure, Body mass index, Age, Neck circumference, Gender) score of ≥3. The patients were randomly divided into twogroups: (I) rocuronium group (Group E) and (II) remifentanil group (Group R). Group R received 4 mcg/kg remifentanil and Group Ereceived 0.6 mg/kg rocuronium and then the patients’ intubation difficulty scale scores and their responses to train-of-four (TOF)nerve stimulation, and postoperative recovery were evaluated in both groups.Results: The median time to recovery of the TOF ratio to 0 following anesthetic induction was significantly higher in Group Rcompared to Group E (p
🔖
Cite This Article
GULHAS, N., YUZKAT, N., TUNCDEMİR, Y. E., SOYALP, C. (2022). Effects of tracheal intubation without muscle relaxants on postoperative recovery conditions in patients with obstructive sleep apnea: A double-blind randomized controlled study. Annals of Medical Research, Cilt: 26 - Sayı: 8, 1658–1665. https://ajindex.com/articles/447016
Acar HV, Kaya A, Yücel F, et al. Validation of the STOP-Bang questionnaire: An obstructive sleep apnoea screening tool in Turkish population. Türk Anestezi ve Reanimsyun Dernegi 2013;41:115
Vasu TS, Grewal R, Doghramji K. Obstructive sleep apnea syndrome and perioperative complications: a systematic review of the literature. J Clin Sleep Med. 2012;8:199-207
Nugent KM, Phy M, Raj R. Obstructive sleep apnea and post-operative complications: single center data, review of literature and guidelines for practicing internists and surgeons. Surg Sci 2012;3:65
Chung F, Abdullah HR, Liao P. STOP-Bang questionnaire: a practical approach to screen for obstructive sleep apnea. Chest 2016;149:631-8
Chung F, Subramanyam R, Liao P, et al. High STOP-Bang score indicates a high probability of obstructive sleep apnoea. Br J Anaesth 2012;108:768-75
Eikermann M, Vogt FM, Herbstreit F, et al. The predisposition to inspiratory upper airway collapse during partial neuromuscular blockade. Am J Respir Crit Care Med 2007;175:9-15
Işıl CT, Sivrikaya GU, Erol MK, et al. Postoperative residual curarisation after rocuronium and atracurium. Turk J Anaesthesiol Reanimation 2011;39:302-10
Ramachandran SK, Pandit J, Devine S, et al. Postoperative respiratory complications in patients at risk for obstructive sleep apnea: a single-institution cohort study. Anesth Analg 2017;125:272-9
Hafeez KR, Tuteja A, Singh M, et al. Postoperative complications with neuromuscular blocking drugs and/ or reversal agents in obstructive sleep apnea patients: a systematic review. BMC Anesthesiol 2018;18:91
Gulhas N, Topal S, Erdogan Kayhan G, et al. Remifentanil without muscle relaxants for intubation in microlaryngoscopy: A double blind randomised clinical trial. Eur Rev Med Pharmacol Sci 2013;17:1967-73
Finkel KJ, Searleman AC, Tymkew H, et al. Prevalence of undiagnosed obstructive sleep apnea among adult surgical patients in an academic medical center. Sleep Med 2009;10:753-8
Chung F, Memtsoudis SG, Ramachandran SK, et al. Society of Anesthesia and Sleep Medicine guidelines on preoperative screening and assessment of adult patients with obstructive sleep apnea. Anesth Analg 2016;123:452
Seet E, Chua M, Liaw CM. High STOP-BANG questionnaire scores predict intraoperative and early postoperative adverse events. Singapore Med J 2015;56:212
Nagappa M, Subramani Y, Chung F. Best perioperative practice in management of ambulatory patients with obstructive