Journals / Annals of Medical Research / 2019 / Cilt: 26 - Sayı: 8

Effects of endoscopic endonasal sinus surgery on nasal flora in patients with chronic rhinosinusitis with nasal polyps

Pages
1683–1687
Publication Date
2022-10-12
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Comparingpreoperative and postoperative culture results according to isolated potential pathogen microorganism types, no statisticallysignificant difference was observed for any microorganism in the potential pathogen group (p>0.05).Conclusion: As a result, no correlation between nasal polyps’ surgery and potential pathogens was detected.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: This study aimed to evaluate the alterations in the nasal flora in patients who underwent endoscopic endonasal surgery forchronic rhinosinusitis with nasal polyps (CRSwNP).Material and Methods: This prospective study included 30 patients diagnosed with CRSwNP who were resistant to medicaltreatment and recommended for surgery.
📊
Key Findings & Data:The nasal cavity was sampled two times, first preoperatively on the day of operation andpostoperatively in the 4th week.
💡
Conclusion & Impact:Comparingpreoperative and postoperative culture results according to isolated potential pathogen microorganism types, no statisticallysignificant difference was observed for any microorganism in the potential pathogen group (p>0.05).Conclusion: As a result, no correlation between nasal polyps’ surgery and potential pathogens was detected.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: This study aimed to evaluate the alterations in the nasal flora in patients who underwent endoscopic endonasal surgery forchronic rhinosinusitis with nasal polyps (CRSwNP).Material and Methods: This prospective study included 30 patients diagnosed with CRSwNP who were resistant to medicaltreatment and recommended for surgery. The nasal cavity was sampled two times, first preoperatively on the day of operation andpostoperatively in the 4th week. Patients were divided into two groups according to their culture results, including normal florabacteria and potential pathogen production.Results: In the preoperative swab samples, 3 (11.1%) patients had no bacterial growth, 16 (59.3%) patients had a normal flora, andpotential pathogens were detected in 8 (29.6%) patients. However, postoperatively, 3 (11.1%) patients had no bacterial growth, 13(48.1%) patients had a normal flora, and potential pathogens were detected in 11 (40.7%) patients during the postoperative period.No significant difference was found between preoperative and postoperative culture results in terms of the number of patientswith normal flora, potential pathogens, and no bacterial growth (p=0.676). The most common microorganism in the normal floragroup preoperative and postoperative period was coagulase-negative Staphylococcus (77.8%, 51.9%, respectively), and the mostcommon microorganism in the potential pathogen group was Staphylococcus aureus (18.5% and 25.9%, respectively). Comparingpreoperative and postoperative culture results according to isolated potential pathogen microorganism types, no statisticallysignificant difference was observed for any microorganism in the potential pathogen group (p>0.05).Conclusion: As a result, no correlation between nasal polyps’ surgery and potential pathogens was detected.

🔖

Cite This Article

MUDERRİS, T., BOZDEMİR, K., KORKMAZ, M. H., KUTLUHAN, A., OGUZHAN, T., ACİKGÖZ, Z. C., ÇALLIOĞLU, E. E., ULUSOY, B. (2022). Effects of endoscopic endonasal sinus surgery on nasal flora in patients with chronic rhinosinusitis with nasal polyps. Annals of Medical Research, Cilt: 26 - Sayı: 8, 1683–1687. https://ajindex.com/articles/446820

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Cope EK, Goldberg AN, Pletcher SD, et al. Compositionally and functionally distinct sinus microbiota in chronic rhinosinusitis patients have immunological and clinically divergent consequences. Microbiome 2017;5:53
  2. Stern S, Hadar T, Nachalon Y, et al. Bacteriology of the middle meatus in chronic rhinosinusitis with and without polyposis. ORL J Otorhinolaryngol Relat Spec 2016;78:223-31
  3. Veloso-Teles R, Cerejeira R. Endoscopic sinus surgery for chronic rhinosinusitis with nasal polyps: Clinical outcome and predictive factors of recurrence. Am J Rhinol Allergy 2017;31:56-62
  4. Rajguru R. Nasal polyposis: current trends. Indian J Otolaryngol Head Neck Surg 2014;66:16-21
  5. Schleimer RP. Immunopathogenesis of chronic rhinosinusitis and nasal polyposis. Annu Rev Pathol 2017;12:331-57
  6. Hamilos DL. Host-microbial interactions in patients with chronic rhinosinusitis. J Allergy Clin Immunol 2014;133:640-53 e4
  7. Alanin MC. Bacteriology and treatment of infections in the upper and lower airways in patients with primary ciliary dyskinesia: adressing the paranasal sinuses. Dan Med J 2017;64:B5361
  8. Bhattacharyya N. Bacterial infection in chronic rhinosinusitis: a controlled paired analysis. Am J Rhinol 2005;19:544-8
  9. Hulse KE, Stevens WW, Tan BK, et al. Pathogenesis of nasal polyposis. Clin Exp Allergy 2015;45:328-46
  10. Bernstein JM, Ballow M, Schlievert PM, et al. A superantigen hypothesis for the pathogenesis of chronic hyperplastic sinusitis with massive nasal polyposis. Am J Rhinol 2003;17:321-6
  11. Ou J, Wang J, Xu Y, et al. Staphylococcus aureus superantigens are associated with chronic rhinosinusitis with nasal polyps: a meta-analysis. Eur Arch Otorhinolaryngol 2014;271:2729-36
  12. Abreu NA, Nagalingam NA, Song Y, et al. Sinus microbiome diversity depletion and Corynebacterium tuberculostearicum enrichment mediates rhinosinusitis. Sci Transl Med 2012;4:151ra24
  13. Kim RJ, Biswas K, Hoggard M, et al. Paired analysis of the microbiota of surface mucus and whole-tissue specimens in patients with chronic rhinosinusitis. Int Forum Allergy Rhinol 2015;5:877-83
  14. Biswas K, Hoggard M, Jain R, et al. The nasal microbiota in health and disease: variation within and between subjects. Front Microbiol 2015;9:134
  15. Lee CW, Lee BJ, Yoo SH, et al. Relationship between positive bacterial culture in maxillary sinus and surgical outcomes in chronic rhinosinusitis with nasal polyps. Auris Nasus Larynx 2014;41:446-9
  16. Uhliarova B, Karnisova R, Sve