Journals / Annals of Medical Research / 2019 / Cilt: 26 - Sayı: 3

Zinc oxide, lidocaine, hot water, and lateral internal sphincterotomy for fissure-in-ano: Randomized controlled study

Pages
355–359
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There was no difference between the non-operative treatments.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Aim of this study is to compare the effect of zinc oxide pomade, lidocaine pomade, hot water sitting bath and lateral internal sphincterotomy for treatment of chronic anal fissure in terms of healing and complications.Material and Methods: One hundred and forty five patients who were diagnosed with chronic anal fissure between May 2011 and September 2012 at our clinic were enrolled for this prospective randomized trial.
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Key Findings & Data:Group 1: The patients would apply 15% of zinc oxide pomade twice a day after the 10 minutes of hot water sitting bath.
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Conclusion & Impact:There was no difference between the non-operative treatments.
🔬Design:Research Article
📍Scope:2011 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: Aim of this study is to compare the effect of zinc oxide pomade, lidocaine pomade, hot water sitting bath and lateral internal sphincterotomy for treatment of chronic anal fissure in terms of healing and complications.Material and Methods: One hundred and forty five patients who were diagnosed with chronic anal fissure between May 2011 and September 2012 at our clinic were enrolled for this prospective randomized trial. All cases were randomized into four groups. Group 1: The patients would apply 15% of zinc oxide pomade twice a day after the 10 minutes of hot water sitting bath. Group 2: The patients would apply 5% of lidocaine pomade twice a day after the 10 minutes of hot water sitting bath. Group 3: The patients would make only 10 minutes of hot water sitting bath twice a day.Group 4: Lateral internal sphincterotomy was performed to the patients.Healing rates, recurrences,changes in symptoms after the treatment and complications were recorded.Results: There were not any difference within the groups in terms of age and gender. The healing in the Sphincterotomy group significantly much more when compared to the other groups at both the third and the sixth weeks(p0,05).Conclusion: LIS is superior to zinc oxide, lidocaine or hot water applications. There was no difference between the non-operative treatments.

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Cite This Article

KARAHAN, Ö., SEVİNÇ, B., OKUS, A., AY, S., AKSOY, N., ERYILMAZ, M. A. (2022). Zinc oxide, lidocaine, hot water, and lateral internal sphincterotomy for fissure-in-ano: Randomized controlled study. Annals of Medical Research, Cilt: 26 - Sayı: 3, 355–359. https://ajindex.com/articles/446687

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References (14)

  1. Nelson RL, Thomas K, Morgan J, et al. Non surgical therapy for anal fissure. Cochrane Database Syst Rev 2012;2:D003431
  2. Lansdown ABG. Zinc in the healing wound. Lancet. 1996;347:706-7
  3. Pories WJ, Henzel JH, Rob CG, et al. Acceleration of wound healing in man with zinc sulphate given by mouth. Lancet 1967;1:121-4
  4. Sunzel B, Lasek J, So¨derberg T, et al. The effect of zinc oxide on Staphylococcus aureus and polymorphonuclear cells in a tissue cage model. Scand J Plast Reconstr Surg Hand Surg 1990;24:31-5
  5. Agren MS, Söderberg TA, Reuterving CO, et al. Effect of topical zinc oxide on bacterial growth and inflammation in full-thickness skin wounds in normal and diabetic rats. Eur J Surg 1991;157 97-101
  6. Acheson AG, Scholefield JH. Anal Fissure: The Changing Management of a Surgical Condition. Langenbecks Arch Surg 2005;390:1-7
  7. Ho SK, Ho HY, Randomized clinical trial comparing oral nifedipine with lateral anal sphincterotomy and tailored sphincterotomy in the treatment of chronic anal fissure. Br J Surg 2005;92:403-8
  8. Hoexter B, Anal Fissure, Fazio WV, et al. Current therapy in colon and rectal surgery. Second Edition, Elsevier Mosby 2005;3:19-22
  9. Arroyo A, Perez F, Serrano P, et al. Open versus closed lateral sphincterotomy performed as an outpatient procedure under local anesthesia for chronic anal fissure: Prospective randomized study of clinical and manometric longterm results. J Am Coll Surg 2004;199:361-7
  10. Charles Orsay, Jan Rakinic, Brian Perry, et al. Practice parameters fort he management of anal fissures (Revised). Dis Colon Rectum 2004;47:2003-7 11. Lindsey I, Jones OM, Cunningham C, et al. Chronic anal fissure. Br J Surg 2004;91:270-9 12. Nivatvongs S. Division of Colon and Rectal Surgery. Kelly AK, Sarr GM, Hinder AR, Mayo Clinic Gastrointestinal Surgery, First Edition, Saunders 2004;42:589-626
  11. Kocher HM, Steward M, Leather AJ, et al. Randomized clinical trial assessing the side effects of glyceryl trinitrate and diltiazem hydrochloride in the treatment of chronic anal fissure. Br J Surg 2002;89:413-7
  12. Ersan Y, Kuşaslan R. Anal fissürlerde medikal tedavi. Cerrahpaşa J Med 2004;35:194-9
  13. Tranqui P, Trottier DC, Victor C, et al. Nonsurgical treatment of chronic anal fissure: nitroglycerin and dilatation versus nifedipine and botulinum toxin. Can J Surg 2006;9;41-5
  14. Thornton MJ, Kennedy ML, King DW. Manometric effect of topical glyceryl trinitrate and its impact on chronic anal fissure healing. Dis Colon