Journals / Annals of Medical Research / 2020 / Cilt: 27 - Sayı: 10

Is there any relationship between the time spent in respiratory events and cardiovascular morbidity in obstructive sleep apnea patients?

Pages
2529–2533
Publication Date
2022-10-12
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, the relationship between apnea-hypopnea index (AHI) and cardiovascular diseases in mild, moderate, severe, and all OSA was not significant.Conclusion: Using parameters including the duration of respiratory events in addition to AHI may be more useful to understand the comorbidities of OSA particularly cardiovascular diseases.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: The importance of the duration of respiratory events, in addition to the number, in the evaluation of obstructive sleep apnea (OSA) is gradually increasing.
📊
Key Findings & Data:Material and Methods: A retrospective study included 200 patients with OSA (100 severe, 50 moderate, 50 mild).
💡
Conclusion & Impact:However, the relationship between apnea-hypopnea index (AHI) and cardiovascular diseases in mild, moderate, severe, and all OSA was not significant.Conclusion: Using parameters including the duration of respiratory events in addition to AHI may be more useful to understand the comorbidities of OSA particularly cardiovascular diseases.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: The importance of the duration of respiratory events, in addition to the number, in the evaluation of obstructive sleep apnea (OSA) is gradually increasing. We aimed to investigate whether parameter including the number and duration of respiratory events predict cardiovascular mortality. Material and Methods: A retrospective study included 200 patients with OSA (100 severe, 50 moderate, 50 mild). Time spent during respiratory events, including the number and duration of respiratory events, was calculated for each respiratory event. Obstructive apnea time (OAT), hypopnea time (HT), total apnea time (TAT), and total respiratory event time (TRET) were obtained. The relationship between cardiovascular diseases of the patients and the time spent during respiratory events was examined. Results: There was no relationship between the cardiovascular diseases and the time spent during respiratory events in the mild, moderate and all OSA group; however, the prolonged OAT (p=0.024) and TAT (p=0.039) in the severe OSA group were associated with an increase in the cardiovascular diseases, independent of other variables. However, the relationship between apnea-hypopnea index (AHI) and cardiovascular diseases in mild, moderate, severe, and all OSA was not significant.Conclusion: Using parameters including the duration of respiratory events in addition to AHI may be more useful to understand the comorbidities of OSA particularly cardiovascular diseases.

🔖

Cite This Article

GÜNEŞ, A., DURMAZ, D. Y., YILDIZ, T. (2022). Is there any relationship between the time spent in respiratory events and cardiovascular morbidity in obstructive sleep apnea patients?. Annals of Medical Research, Cilt: 27 - Sayı: 10, 2529–2533. https://ajindex.com/articles/446086

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Peppard PE, Young T, Barnet JH, et al. Increased prevalence of sleep-disordered breathing in adults. Am J Epidemiol 2013;177:1006-14
  2. Zhan X, Fang F, Wu C, et al. A Retrospective Study to Compare the Use of the Mean Apnea-Hypopnea Duration and the Apnea-Hypopnea Index with Blood Oxygenation and Sleep Patterns in Patients with Obstructive Sleep Apnea Diagnosed by Polysomnography. Med Sci Monit 2018;24:1887-93
  3. Sarac S, Afsar GC. Effect of mean apnea-hypopnea duration in patients with obstructive sleep apnea on clinical and polysomnography parameter. Sleep Breath 2020:24:77-81
  4. Butler MP, Emch JT, Rueschman M, et al. Apnea- Hypopnea Event Duration Predicts Mortality in Men and Women in the Sleep Heart Health Study. Am J Respir Crit Care Med 2019;199:903-12
  5. Yılmaz Durmaz D, Gunes A. Which is more important: the number or duration of respiratory events to determine the severity of obstructive sleep apnea? Aging Male 2020;23:119-24
  6. Leppänen T, Kulkas A, Mervaala E, et al. Increase in Body Mass Index Decreases Duration of Apneas and Hypopneas in Obstructive Sleep Apnea. Respir Care 2019;64:77-84
  7. Kulkas A, Tiihonen P, Eskola K, et al. Novel parameters for evaluating severity of sleep disordered breathing and for supporting diagnosis of sleep apnea-hypopnea syndrome. J Med Eng Technol 2013;37:135-43
  8. Wu H, Zhan X, Zhao M, et al. Mean apnea-hypopnea duration (but not apnea-hypopnea index) is associated with worse hypertension in patients with obstructive sleep apnea. Medicine (Baltimore) 2016;95:5493
  9. Kulkas A, Tiihonen P, Julkunen P, et al. Novel parameters indicate significant differences in severity of obstructive sleep apnea with patients having similar apnea-hypopnea index. Med Biol Eng Comput 2013;51:697-708
  10. LJ Laslett, P Alagona, BA Clark, et al. The Worldwide Environment of Cardiovascular Disease: Prevalence, Diagnosis, Therapy, and Policy Issues: A Report From the American College of Cardiology. J Am Coll Cardiol 2012;60:1-49
  11. Tietjens JR, Claman D, Kezirian EJ, et al. Obstructive Sleep Apnea in Cardiovascular Disases: A Review of the Literature and Proposed Multidisciplinary Clinical Management Strategy. J Am Heart Assoc 2019;8:010440
  12. Wu H, Lv Q, Zhang H, et al. The reduction of apneahypopnea duration ameliorates endothelial dysfunction, vascular inflammation, and systemic hypertension in a rat model of obstructive sleep apnea. Sleep Breath 2019;23:1187-96
  13. Leppänen T, Särkkä M, Kulkas A, et al. RemLogic plu