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Journals / Annals of Medical Research / 2021 / Cilt: 28 - Sayı: 3

Antimicrobial activity of sapindus mukorossi andsaponaria officinalis extracts on streptococcus mutansand enterococcus faecalis

Meltem Mert Eren
Hüseyin Servi
Günçe Ozan
Benin Dikmen
Cansu Vatansever
Hulki Caner Yeğin
Pages
516–519
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

They may be used as an ingredient in dental agents.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Studies on the antimicrobial effectiveness of saponins against oral pathogens are conflicting.
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Key Findings & Data:Therefore, this study aimed toevaluate the antimicrobial activity of saponins from three different extracts of Sapindus mukorossi and Saponaria officinalis plantsagainst Streptococcus mutans and Enterococcus faecalis.Materials and Methods: The fruit of Sapindus mukorossi and the root of Saponaria officinalis materials were sliced into small piecesand macerated with hexane, ethyl acetate (EtOAc) and methanol (MeOH), in this order.
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Conclusion & Impact:They may be used as an ingredient in dental agents.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: Studies on the antimicrobial effectiveness of saponins against oral pathogens are conflicting. Therefore, this study aimed toevaluate the antimicrobial activity of saponins from three different extracts of Sapindus mukorossi and Saponaria officinalis plantsagainst Streptococcus mutans and Enterococcus faecalis.Materials and Methods: The fruit of Sapindus mukorossi and the root of Saponaria officinalis materials were sliced into small piecesand macerated with hexane, ethyl acetate (EtOAc) and methanol (MeOH), in this order. The antimicrobial activity of the extractsagainst Streptococcus mutans and Enterococcus faecalis was determined by the broth microdilution method based on the minimuminhibitory concentrations (MIC) of each extract. Results: Except for the hexane extract of Saponaria Officinalis, all extracts of both plants had an inhibitory activity against thetested microorganisms. Higher MIC values were obtained against Enterococcus faecalis than Streptococcus Mutans. The lowestMIC values for both Sapindus mukorossi and Saponaria officinalis were against Streptococcus mutans (4 mg/ml).Conclusion: Saponins extracted from Sapindus mukorossi and Saponaria officinalis have a potential antibacterial activity againstoral pathogens. They may be used as an ingredient in dental agents.

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Cite This Article

Eren, M. M., Servi, H., Ozan, G., Dikmen, B., Vatansever, C., Yeğin, H. C. (2022). Antimicrobial activity of sapindus mukorossi andsaponaria officinalis extracts on streptococcus mutansand enterococcus faecalis. Annals of Medical Research, Cilt: 28 - Sayı: 3, 516–519. https://ajindex.com/articles/445929

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