Based on CT findings, pneumonic type-IMA was associated with a more advanced stage (p
📌 3 Key Takeaways
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Objective & Hypothesis:Aim: The aim of our study is to evaluate the cases with invasive mucinous adenocarcinoma (IMA) detected separately from lung adenocarcinoma in the 2015 WHO classification and to associate the clinicopathological findings and evaluate their prognostic significance based on computed tomography (CT) findings.Materials and Methods: The materials of patients who underwent resection from January 1 2011 to June 31 2019 at our hospital were reviewed after archive screening and those belonging to the Invasive mucinous adenocarcinoma group were determined according to the WHO 2015 classification.
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Key Findings & Data:Tumors were classified as solitary or pneumonic type based on CT findings, and the data obtained were compared statistically.Results: Based on CT findings (pneumonic and solitary), pathological T stages were significantly different between the two groups.
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Conclusion & Impact:Based on CT findings, pneumonic type-IMA was associated with a more advanced stage (p
🔬Design:Review & Systematic Survey
📍Scope:2015 Verileri
⚙️Variables:Domain Parameters
Abstract
Aim: The aim of our study is to evaluate the cases with invasive mucinous adenocarcinoma (IMA) detected separately from lung adenocarcinoma in the 2015 WHO classification and to associate the clinicopathological findings and evaluate their prognostic significance based on computed tomography (CT) findings.Materials and Methods: The materials of patients who underwent resection from January 1 2011 to June 31 2019 at our hospital were reviewed after archive screening and those belonging to the Invasive mucinous adenocarcinoma group were determined according to the WHO 2015 classification. Clinical and radiological data of the cases were collected. Tumors were classified as solitary or pneumonic type based on CT findings, and the data obtained were compared statistically.Results: Based on CT findings (pneumonic and solitary), pathological T stages were significantly different between the two groups. Based on CT findings, pneumonic type-IMA was associated with a more advanced stage (p
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Cite This Article
ÜRER, H. N., ÜNVER, N., FENER, N. A. (2022). Evaluation of clinicopathological characteristics andprognosis of lung ınvasive mucinous adenocarcinomasbased on computed tomography (CT) findings. Annals of Medical Research, Cilt: 28 - Sayı: 8, 1445–1449. https://ajindex.com/articles/445722
Nie K, Nie W, Zhang YX, et al. Comparing clinicopathological features and prognosis of primary pulmonary invasive mucinous adenocarcinoma based on computed tomography findings. Cancer Imaging 2019
47 2. Suárez-Piñera M, Belda-Sanchis J, Taus A, et al. FDG PET-CT SUVmax and IASLC/ATS/ERS histologic classification: a new profile of lung adenocarcinoma with prognostic value. Am J Nucl Med Mol Imaging 2018
Moon SW, Choi SY, Moon MH. Effect of invasive mucinous adenocarcinoma on lung cancer-specific survival after surgical resection: a population-based study. J Thorac Dis 2018:3595-608. 4. Lee HY, Cha MJ, Lee KS, et al. Prognosis in Resected Invasive Mucinous Adenocarcinomas of the Lung: Related Factors and Comparison with Resected Nonmucinous Adenocarcinomas. J Thorac Oncol 2016
73 5. Travis WD, Brambilla E, Nicholson AG, et al. WHO Panel. The 2015 World Health Organization Classification of Lung Tumors: Impact of Genetic, Clinical and Radiologic Advances Since the 2004 Classification. J Thorac Oncol 2015
Sun F, Wang P, Zheng Y, et al. Diagnosis, clinicopathological characteristics and prognosis of pulmonary mucinous adenocarcinoma. Oncol Lett 2018
Yoshizawa A, Motoi N, Riely GJ, et al. Impact of proposed IASLC/ATS/ERS classification of lung adenocarcinoma: prognostic subgroups and implications for further revision of staging based on analysis of 514 stage I cases. Mod Pathol 2011
Watanabe H, Saito H, Yokose T, et al. Relation between thin-section computed tomography and clinical findings of mucinous adenocarcinoma. Ann Thorac Surg 2015
Cha MJ, Lee KS, Kim TJ, et al. Solitary Nodular Invasive Mucinous Adenocarcinoma of the Lung: Imaging Diagnosis Using the Morphologic-Metabolic Dissociation Sign Korean J Radiol 2019
Yoshizawa A, Sumiyoshi S, Sonobe M, et al. Validation of the IASLC/ATS/ERS lung adenocarcinoma classification for prognosis and association with EGFR and KRAS gene mutations: analysis of 440 Japanese patients. J Thorac Oncol 2013
Shim HS, Kenudson M, Zheng Z, et al. Unique Genetic and Survival Characteristics of Invasive Mucinous Adenocarcinoma of the Lung. J Thorac Oncol 2015
Shimizu K, Okita R, Saisho S, et al. Clinicopathological and immunohistochemical features of lung invasive mucinous adenocarcinoma based on computed tomography findings. Onco Targets Ther 2016