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Journals / Annals of Medical Research / 2022 / Cilt: 29 - Sayı: 4

Evaluation of posterior segment ocular parameters in patients with pediatric familial mediterranean fever

Mustafa ÇAPRAZ
Melek TÜFEK
Nihat AYDIN
Pınar NALCACIOĞLU
İrfan ARIKAN
Pages
310–314
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: This study shows that the recurrent inflammation caused by FMF can affect choroidal thickness and peripapillary RNFL in children.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: We aimed to compare the ocular posterior segment parameters in pediatric patients with Familial Mediterranean Fever (FMF) with a healthy control group.
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Key Findings & Data:Materials and Methods: We evaluated 40 pediatric FMF patients and 36 healthy children in this study.
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Conclusion & Impact:Conclusion: This study shows that the recurrent inflammation caused by FMF can affect choroidal thickness and peripapillary RNFL in children.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: We aimed to compare the ocular posterior segment parameters in pediatric patients with Familial Mediterranean Fever (FMF) with a healthy control group. Materials and Methods: We evaluated 40 pediatric FMF patients and 36 healthy children in this study. Choroidal thicknesses from the subfoveal, nasal and temporal 500 µm, 1000 µm, and 1500 µm points; the subfoveal macular thickness; macular volume; optic nerve head (ONH) parameters; and peripapillary retinal nerve fiber layer (RNFL) thickness were measured. An optical coherence tomography (OCT) device was used for measurements. Results: The choroidal thickness in the temporal 1500 µm was significantly thinner, and average peripapillary RNFL thickness was significantly lower in the FMF group compared to the control group (p = 0.015 and p = 0.023, respectively). The groups were similar in terms of macular thickness and macular volume. Among the ONH parameters, the rim area thickness was also significantly higher in the FMF group (p = 0.013). Conclusion: This study shows that the recurrent inflammation caused by FMF can affect choroidal thickness and peripapillary RNFL in children.

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Cite This Article

ÇAPRAZ, M., TÜFEK, M., AYDIN, N., NALCACIOĞLU, P., ARIKAN, İ. (2022). Evaluation of posterior segment ocular parameters in patients with pediatric familial mediterranean fever. Annals of Medical Research, Cilt: 29 - Sayı: 4, 310–314. https://ajindex.com/articles/445584

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