Journals / Ankara Üniversitesi Veteriner Fakültesi Dergisi / 2007 / Cilt: 54 - Sayı: 3

Serum adenosine diaminase activity and nitric oxide level in cows xith trichopyhtosis

Trikofitozisli ineklerde serum adenozin deaminaz aktivitesi (ADA) ve nitrik oksit (NO) düzeyleri

Pages
155–158
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We thought that, this increase related to newly iNOS release and NO producing in macrophages.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Trichophytosis which caused by Trichophyton spp. is an enzootic skin disease.
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Key Findings & Data:Thirty cattles with thrichophytosis and 10 healthy cattles were used in the study.
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Conclusion & Impact:We thought that, this increase related to newly iNOS release and NO producing in macrophages.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Trichophytosis which caused by Trichophyton spp. is an enzootic skin disease. In this study, effects of trichophytosis on serum adenozine deaminase (ADA) and nitric oxide (NO) activities were investigated. Thirty cattles with thrichophytosis and 10 healthy cattles were used in the study. Average ages of the cattle were 1-3 and average body weight was 250 kg. Blood samples were taken from vena jugularis of the animals. Serum ADA activities and NO levels were detected with spectrophotomethric method. Serum ADA activities were detected 12.70 U/L and 24.49 U/L in research and control groups respectively. Statistically difference was important between two groups (p0.05). Consequently, we thought that, serum ADA levels might be increased by cell mediated immune system which was stimulated by T. verricosum. Although, NO levels were monitored slightly increase in research group. We thought that, this increase related to newly iNOS release and NO producing in macrophages.

Özet

Bu çalışmada trikofitozisli ineklerde serum adenozin deaminaz (ADA) aktivitesinin ve nitrik oksit (NO) seviyesinin nasıl etkilendiği araştırıldı. Çalışmada 1-3 yaşlarında, ortalama 250 kg canlı ağırlığında trikofitozisli olduğu belirlenen 30 adet yerli ırk sığır ile 10 adet sağlıklı yerli ırk sığır kullanıldı. Hayvanların vena jugularisinden kan alınarak serumları çıkartıldı. Serumda ADA aktivitesi ve NO düzeyi spekrofotometrik olarak ölçüldü. Serum ADA aktivitesi kontrol ve trikofitozisli sığırlarda sırasıyla 12.70 U/L ve 24.49 U/L olarak tespit edildi. ADA aktivitesinde gruplar arasındaki farklılık istatistiksel olarak önemli bulundu (p0.05). Sonuç olarak serum ADA aktivitesinin T.verricosum tarafından hücre aracılı immun sistemin uyarılması sayesinde artmış olabileceği düşünüldü. Buna karşın araştırma grubunda kontrole göre serum NO seviyesinin ortalamasında relatif olmayan bir artış gözlendi. Bu artış, makrofajlardaki iNOS salınımının ve NO üretiminin yeni başlamış olabileceğini düşündürdü.

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Cite This Article

ÇİFTÇİ, A., NİSBET, C., ARSLAN, H. H., YARIM, G. F., ÇENESİZ, S. (2022). Serum adenosine diaminase activity and nitric oxide level in cows xith trichopyhtosis. Ankara Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 54 - Sayı: 3, 155–158. https://ajindex.com/articles/445142

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