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Journals / Ankara Üniversitesi Veteriner Fakültesi Dergisi / 2009 / Cilt: 56 - Sayı: 4

Köpeklerde sevofluran, izofluran ve halotan anestezilerinin spontan ve kontrollü ventilasyon sırasındaki kardiyopulmoner etkileri

The cardiopulmonary effects of sevoflurane, isoflurane and halothane anesthesia during spontaneous or controlled ventilation in dogs

Ayşe TOPAL
Göksen ÇEÇEN
O.Sacit GORGÜL
Semra AKGÖZ
Pages
255–261
Publication Date
2022-10-12
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

RR decreased significantly during ISO and HAL anesthesia in SV (p

📌 3 Key Takeaways

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Objective & Hypothesis:The objective of this study was to investigate the cardiopulmonary effects of sevoflurane (SEV), isoflurane (ISO) and halothane (HAL) anesthesia during spontaneous ventilation (SV) or controlled ventilation (CV) in dogs.
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Key Findings & Data:Dogs were randomly allocated to six anesthesia groups (n = 10 in each group): SEV/SV; SEV/CV; ISO/SV; ISO/CV; HAL/SV; HAL/CV.
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Conclusion & Impact:RR decreased significantly during ISO and HAL anesthesia in SV (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The objective of this study was to investigate the cardiopulmonary effects of sevoflurane (SEV), isoflurane (ISO) and halothane (HAL) anesthesia during spontaneous ventilation (SV) or controlled ventilation (CV) in dogs. An experimental study was designed. Sixty healthy cross breed dogs were used for the study. Dogs were randomly allocated to six anesthesia groups (n = 10 in each group): SEV/SV; SEV/CV; ISO/SV; ISO/CV; HAL/SV; HAL/CV. After premedication with xylazine HCl, anesthesia was induced with thiopental sodium. Inhalation anesthesia was maintained for 90 minutes with SEV, ISO, or HAL. Cardiopulmonary parameters [heart rate (HR), respiratory rate (RR), mean arterial blood pressure (MAP), end tidal carbon dioxide level (ETCO2), oxygen saturation (SpO2), central venous pressure (CVP), body temperature, arterial partial pressure of oxygen (PaO2), arterial partial pressure of carbon dioxide (PaCO2), and arterial pH] were measured after induction of anesthesia; the first measurement was taken one minute after the loss of consciousness with SEV, ISO, or HAL and the others were done at 15th, 30th, 45th, 60th and 90th minutes. There was not any significant difference in HR between anesthetics among SV and CV. RR decreased significantly during ISO and HAL anesthesia in SV (p

Özet

Bu çalışma ile köpeklerde spontan ventilasyon (SV) ve kontrollü ventilasyon (CV) sırasında sevofluran (SEV), izofluran (ISO) ve halothan (HAL) anestezilerinin kardiyopulmoner etkilerinin incelenmesi amaçlandı. Çalışma deneysel olarak planlandı ve çalışmada 60 sağlıklı melez köpek kullanıldı. Köpekler eşit olacak şekilde rastgele 6 anestezi grubuna ayrıldı: SEV/SV; SEV/CV; ISO/SV; ISO/CV; HAL/SV; HAL/CV. Xylazine HCL ile premedikasyonu takiben indüksiyon thiopental sodium ile yapıldı ve SEV, ISO ve HAL ile 90 dakika boyunca inhalasyon anestezisi oluşturuldu. Kardiyopulmoner parametreler [kalp frekansı (HR), solunum sayısı (RR), ortalama arteriyel kan basıncı (MAP), solunum sonu karbondioksit düzeyi (ETCO2), oksijen saturasyonu (SpO2), sentral venöz basınç (CVP), beden ısısı, parsiyel arteriyel oksijen basıncı (PaO2), parsiyel arteriyel karbondioksit basıncı (PaCO2) ve arteriyel pH] ölçüldü. İlk ölçüm değeri, inhalasyon anestezikleri ile bilincin kaybolmasından bir dakika sonra, diğer ölçüm değerleri ise 15., 30., 45. 60. ve 90. dakikalarda kaydedildi. HR’de anestezik maddeler arasında SV ve CV sırasında belirgin bir farklılık kaydedilmedi. SV’de ISO ve HAL anestezileri ile RR anlamlı şekilde azaldı (p

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Cite This Article

TOPAL, A., ÇEÇEN, G., GORGÜL, O., AKGÖZ, S. (2022). Köpeklerde sevofluran, izofluran ve halotan anestezilerinin spontan ve kontrollü ventilasyon sırasındaki kardiyopulmoner etkileri. Ankara Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 56 - Sayı: 4, 255–261. https://ajindex.com/articles/445026

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