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Journals / Ankara Üniversitesi Veteriner Fakültesi Dergisi / 2013 / Cilt: 60 - Sayı: 1

Nörodejeneratif hastalıkların tedavisinde yeni bir strateji: Nörosteroidler

A new strategy in treatment of neurodegenerative diseases: Neurosteroids

Gül Fatma YARIM
Pages
79–83
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Neurosteroids reduces the disorders associated with nervous system in neurodegenerative diseases and can be used as preventive and therapeutic in these diseases.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Steroid synthesized from cholesterol in the central nervous system independently of gonads and adrenal glands has been defined as neurosteroids.
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Key Findings & Data:Neurosteroids are synthesized in many species of vertebrate and invertebrate nervous systems.
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Conclusion & Impact:Neurosteroids reduces the disorders associated with nervous system in neurodegenerative diseases and can be used as preventive and therapeutic in these diseases.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Steroid synthesized from cholesterol in the central nervous system independently of gonads and adrenal glands has been defined as neurosteroids. Neurosteroids are synthesized in many species of vertebrate and invertebrate nervous systems. Neurosteroids affects the many brain functions. The expression of enzymes catalyzing the synthesis of neurosteroids and the neurosteroid levels are changes in diseases of the nervous system. It has been well documented that neurosteroids protective role on the neurons. Neurosteroids reduces the disorders associated with nervous system in neurodegenerative diseases and can be used as preventive and therapeutic in these diseases.

Özet

Merkezi sinir sisteminde gonadlardan ve adrenal bezlerden bağımsız olarak kolesterolden sentezlenen steroid nörosteroid olarak tanımlanır. Pek çok omurgalı ve omurgasız canlıların sinir sisteminde nörosteroidler sentezlenmektedir. Nörosteroidler pek çok beyin fonksiyonunu etkilemektedir. Sinir sistemi hastalıklarında nörosteroid sentezini katalizleyen enzimlerin ekspresyonları ve nörosteroid düzeyleri değişmektedir. Nörosteroidlerin nöronlar üzerinde koruyucu etkiye sahip olduğu iyi bilinmektedir. Nörosteroidler nörodejeneratif hastalıklarda sinir sistemine ilişkin bozuklukları hafifletmekte, koruyucu ve tedavi edici olarak kullanılabilmektedir.

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Cite This Article

YARIM, G. F. (2022). Nörodejeneratif hastalıkların tedavisinde yeni bir strateji: Nörosteroidler. Ankara Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 60 - Sayı: 1, 79–83. https://ajindex.com/articles/444845

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