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Journals / Ankara Üniversitesi Veteriner Fakültesi Dergisi / 2018 / Cilt: 65 - Sayı: 3

Immunohistochemical investigation of the damage to and repair of myelin, and astrocyte activity in small ruminants resulting from with natural meningoencephalitic listeriosis

Küçük ruminantlardaki doğal meningoensefalitik listerioziste miyelin hasar ve onarımı ile astrosit aktivitesinin immunohistokimyasal olarak incelenmesi

Osman Safa TERZİ
Oğuz KUL
Şule Yurdagül ÖZSOY
Zafer ÖZYILDIZ
Güngör Çağdaş DİNÇEL
Pages
283–290
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

We examined sections of pons, medulla oblongata, rostral colliculus, cerebellum, thalamus and cornu ammonis and found increased MBP (P

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Meningoencephalitic listeriosis is a significant bacterial disease in various species.
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Key Findings & Data:Common characteristics include microabscesses in the brainstem, midbrain and cerebellum.
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Conclusion & Impact:We examined sections of pons, medulla oblongata, rostral colliculus, cerebellum, thalamus and cornu ammonis and found increased MBP (P
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Meningoencephalitic listeriosis is a significant bacterial disease in various species. Common characteristics include microabscesses in the brainstem, midbrain and cerebellum. Many aspects of damage to the central nervous system caused by the disease remain obscure. We investigated central nervous system damage by assessing the presence of biomarkers such as galactocerebroside (GAL-C), glial fibrilary acidic protein (GFAP) and myelin basic protein (MBP) in brain tissues of sheep and goats of various ages, which naturally infected with listeriosis. We examined sections of pons, medulla oblongata, rostral colliculus, cerebellum, thalamus and cornu ammonis and found increased MBP (P

Özet

Meningoencephalitic listeriosis çeşitli türlerde önemli bir bakteriyel hastalıktır. Hastalığın karakteristik özelliği beyin sapı, orta beyin ve beyincikte görülen mikroapselerdir. Hastalık sebebiyle merkezi sinir sisteminde meydana gelen hasarlar birçok açıdan hala belirsizliğini korumaktadır. Bu çalışmada, listeriozis ile doğal enfekte değişik yaşlardaki küçük ruminantların merkezi sinir sistemlerinde görülen hasarın varlığı, galaktoserebrosid (GAL-C), glial fibrilary asidik protein (GFAP) ve miyelin temel protein (MBP) gibi biyolojik belirteçlerle araştırıldı. Pons, medulla oblongata, colliculus rostralis, cerebellum, thalamus ve cornu ammonis gibi bölümler incelendi ve beyin hasarını gösteren MBP (P

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Cite This Article

TERZİ, O. S., KUL, O., ÖZSOY, Ş. Y., ÖZYILDIZ, Z., DİNÇEL, G. Ç. (2022). Immunohistochemical investigation of the damage to and repair of myelin, and astrocyte activity in small ruminants resulting from with natural meningoencephalitic listeriosis. Ankara Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 65 - Sayı: 3, 283–290. https://ajindex.com/articles/444600

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