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Journals / Ankara Üniversitesi Veteriner Fakültesi Dergisi / 2019 / Cilt: 66 - Sayı: 2

Relationship between seropositivity of Encephalitozoon cuniculi and renal biochemical markers in clinically healthy rabbits

Sağlıklı tavşanlarda Encephalitozoon cuniculi seropozitifliği ile böbrek biyokimyasal belirteçleri arasındaki ilişki

Özcan ÖZKAN
Banuçiçek YÜCESAN
Selçuk PEKKAYA
Mehmet Eray ALÇIĞIR
İsmayil Safa GÜRCAN
Pages
197–204
Publication Date
2022-10-12
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

According to histopathological findings in the kidney, degenerative changes and E. cuniculi spores were identified in the tubule epithelia.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Encephalitozoon cuniculi can cause latent disease, especially in lagomorphs and many wild and domestic animals in various countries.
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Key Findings & Data:In a laboratory rabbit breeding facility, enzyme-linked immunosorbent assay (ELISA) tests showed that 48 (49.5%) of 97 rabbits were seropositive against E. cuniculi.
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Conclusion & Impact:According to histopathological findings in the kidney, degenerative changes and E. cuniculi spores were identified in the tubule epithelia.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Encephalitozoon cuniculi can cause latent disease, especially in lagomorphs and many wild and domestic animals in various countries. This infection is important for veterinary and public health because it is caused by a potentially zoonotic and opportunistic pathogen. The aim of this study was to investigate the relationship between seropositivity of E. cuniculi and renal function markers, which may be useful in predicting the disease in clinically healthy rabbits. In this study, the seropositivity of E. cuniculi infection in clinically healthy rabbits was determined, and necropsy findings were evaluated along with the results of renal function tests. In a laboratory rabbit breeding facility, enzyme-linked immunosorbent assay (ELISA) tests showed that 48 (49.5%) of 97 rabbits were seropositive against E. cuniculi. Blood urea nitrogen (BUN) and creatinine levels were significantly elevated in seropositive animals. Two seropositive rabbits were necropsied to confirm the infection. According to histopathological findings in the kidney, degenerative changes and E. cuniculi spores were identified in the tubule epithelia. Serum creatinine (p

Özet

Encephalitozoon cuniculi, özellikle tavşangillerde ve çeşitli ülkelerdeki birçok yaban ve evcil hayvanlarda latent hastalığa neden olabilmektedir. Bu enfeksiyon potansiyel olarak zoonotik ve fırsatçı bir patojenden kaynaklandığından veteriner ve halk sağlığı için önemlidir. Bu çalışmanın amacı, klinik olarak sağlıklı tavşanlarda E. cuniculi seropozitifliği ve böbrek fonksiyon belirteçleri arasındaki ilişkinin, hastalığın tanısında yararlı olabileceğini araştırmaktır. Bu çalışmada, sağlıklı tavşanlarda E. cuniculi enfeksiyonunun seropozitifliği enzim bağlantılı immünosorbent testi (ELISA) ile belirlenmiş ve böbrek fonksiyon test sonuçları ile otopsi bulguları birlikte değerlendirilmiştir. Bir laboratuvar tavşan yetiştirme tesisinde, ELISA testi, 97 tavşanın 48'inin (%49.5) E. cuniculi'ye karşı seropozitif olduğunu göstermiştir. Seropozitif hayvanlarda kan üre nitrojen (BUN) ve kreatinin düzeyleri anlamlı olarak yüksek bulunmuştur. Serum kreatinin (p

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Cite This Article

ÖZKAN, Ö., YÜCESAN, B., PEKKAYA, S., ALÇIĞIR, M. E., GÜRCAN, İ. S. (2022). Relationship between seropositivity of Encephalitozoon cuniculi and renal biochemical markers in clinically healthy rabbits. Ankara Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 66 - Sayı: 2, 197–204. https://ajindex.com/articles/444503

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