Journals / Ankara Üniversitesi Veteriner Fakültesi Dergisi / 2019 / Cilt: 66 - Sayı: 4

Clinical approaches for genital and extragenital metastasis of transmissible venereal tumor in a bitch with ovarian remnant syndrome

Ovaryan remnant sendromlu bir köpekte bulaşıcı veneral tümörün genital ve ekstragenital metastazlarına klinik yaklaşımlar

Pages
417–421
Publication Date
2022-10-12
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It was concluded that evaluation of the metastases with doppler ultrasonography will be favorable to reveal the hemodynamic alterations of related organs or tissues.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A 25 kg, 4 years old, Boxer breed bitch which had ovariohysterectomy section 2 years ago, was presented with weakness, loss of appetite, masses on abdominal and inguinal mammary glands and vaginal bleeding.
📊
Key Findings & Data:Transmissible venereal tumor (TVT) was diagnosed with vaginal cytology.
💡
Conclusion & Impact:It was concluded that evaluation of the metastases with doppler ultrasonography will be favorable to reveal the hemodynamic alterations of related organs or tissues.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A 25 kg, 4 years old, Boxer breed bitch which had ovariohysterectomy section 2 years ago, was presented with weakness, loss of appetite, masses on abdominal and inguinal mammary glands and vaginal bleeding. Transmissible venereal tumor (TVT) was diagnosed with vaginal cytology. Intra-abdominal mass around the iliac artery and remnant ovary behind the right kidney were determined on ultrasonographic examination. The remnant ovary and the masses on mammary glands were removed by surgical approach. However, intra-abdominal mass could not be extirpated because of its localization during the same laparotomy. A biopsy was taken from the vaginal mass. According to histopathology, TVT and collagenous hamartoma were detected on mammary glands. Also, TVT was observed in vaginal and intra-abdominal masses. Chemotherapy protocol was arranged for intra-abdominal mass and vaginal TVT which occupied for ten weeks. Hemogram, vaginal smear and transabdominal ultrasonography were repeated before each chemotherapy course. Size of the intra-abdominal mass, pulsatility index (PI) and relative index (RI) values of iliac artery were evaluated with B-mode ultrasonography and doppler ultrasonography during the treatment, respectively. As a result, positive correlation between PI and RI values were determined. In the presented case, TVT and its metastases were successfully treated with both surgery and chemotherapy. It was concluded that evaluation of the metastases with doppler ultrasonography will be favorable to reveal the hemodynamic alterations of related organs or tissues.

Özet

Dört yaşında, 25 kg ağırlığında, 2 yıl önce ovariohisterektomi operasyonu uygulanmış, Boxer ırkı dişi bir köpek; halsizlik, iştahsızlık, vajinal kanama, abdominal ve inguinal meme bezlerinde kitle şikayetiyle getirildi. Vajinal sitolojik muayene ile bulaşıcı veneral tümör (TVT) teşhis edildi. Ultrasonografik muayenede, arteria iliaka etrafında yer alan intra-abdominal bir kitle ve sağ böbreğin gerisinde kalıntı ovaryum varlığı tespit edildi. Kalıntı ovaryum ve meme bezlerindeki kitleler cerrahi yaklaşım ile uzaklaştırıldı. Laparotomi sırasında intra-abdominal kitle lokalizasyonu nedeniyle esktirpe edilemedi. Vajinal kitleden biyopsi örneği alındı. Histopatolojik inceleme neticesinde, meme bezlerinde TVT ve kollajenöz hamartom, vajinal ve intrabominal kitlelerde de TVT varlığı saptandı. Vaginal ve intra-abdominal TVT kitleleri için 10 haftalık kemoterapi protokolü oluşturuldu. Her kemoterapi öncesi hemogram, vajinal smear ve transabdominal ultrasonografi tekrarlandı. Tedavi süresince intra-abdominal kitlenin boyutu ve arteria illiaka’ya ait pulsatil indeks (PI) ve relative indeks (RI) değerleri sırasıyla B-mod ultrasonografi ve doppler ultrasonografi ile değerlendirildi. Bunun sonucunda, PI ve RI değerleri arasında pozitif korelasyon tespit edildi. Sunulan bu vakada, TVT ve metastazları hem cerrahi yaklaşımla hem de kemoterapi ile başarılı bir şekilde tedavi edildi. Metastazların doppler ultrasonografi ile değerlendirilmesinin, ilgili organ veya dokuların hemodinamik değişikliklerini ortaya koymak için faydalı olacağı sonucuna varıldı

🔖

Cite This Article

BAMAÇ, Ö. E., UÇMAK, M., GÜREL, A., UÇMAK, Z. G., KIRŞAN, İ. (2022). Clinical approaches for genital and extragenital metastasis of transmissible venereal tumor in a bitch with ovarian remnant syndrome. Ankara Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 66 - Sayı: 4, 417–421. https://ajindex.com/articles/444501

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Amber EI, Henderson RA, Adeyanju JB, et al (1990): Single-drug chemotherapy of canine transmissible venereal tumour with cyclophosphamide, methotrexate or vincristine. J Vet Intern Med, 4, 144–147
  2. Bartyzel BJ, Max A, Gruszczynska J, et al (2017): Hamartoma: a rare developmental disorder. Med Weter, 73(4), 202-207
  3. Baştan A, Baki Acar D, Cengiz M (2008): Uterine and ovarian metastasis of transmissible venereal tumor in bitch. Turk J Vet Anim Sci, 32(1), 65-66
  4. Behera SK, Kurade NP, Monsang SW, et al (2012): Clinico-pathological findings in a case of canine cutaneous metastatic transmissible venereal tumor. Vet Arhiv, 82(4), 401-410
  5. Betamuzi EK (1992): Risk factors associated with canine TVT in Tanzania. Prevent Vet Med, 13, 13-17
  6. Boscos CM, Ververidis HN (2004): TVT-Clinical findings, diagnosis and treatment. Proceedings of the 29th World Congress of the World Small Animal Veterinary Association
  7. Castro KF, Strakova A, Tinucci-Costa M, et al (2017): Evaluation of a genetic assay for canine transmissible venereal tumour diagnosis in Brazil. Vet Comp Oncol, 15(2), 615-618
  8. Champour M, Ojrati N, Nikrou A, et al (2014): First report of diffuse cutaneous canine transmissible venereal tumor in Iran. Comp Clin Pathol, DOI 10.1007/s00580-014-1973-z 9. Çizmeci SÜ, Köse AM, Aydın İ, et al (2012): Transmissible venereal tümörlü dişi köpeklerde otojen aşı uygulaması. Eurasian J Vet Sci, 28(4), 220-223
  9. Çizmeci SÜ, Köse AM, Aydın İ, et al (2012): Clinical efficiency of Doxorubicin and Cisplatin in treatment of transmissible venereal tumor of bitches. Revue Méd Vét, 163(11), 516-521
  10. Das U, Das AK (2000): Review of canine transmissible venereal sarcoma. Vet Res Commun, 24, 545-556
  11. Ferreira AJA, Jaggy A, Varejao AP, et al (2000): Brain and ocular metastases from a transmissible venereal tumour in a dog. J Small Anim Pract, 41, 165-168
  12. Ganguly B, Das U, Das AK (2016): Canine transmissible venereal tumour: a review. Vet Comp Oncol, 14(1), 1-12
  13. Gurel A, Kuscu B, Gulanber G, et al (2002): Transmissible venereal tumors detected in the extragenital organs of dogs. Israel J Vet Med, 57(2), 23-26
  14. Jacob A, Bhanuprakash AG, Choudhary SS, et al (2015): Therapeutic management of transmissible venereal tumor in canine. Indian J Vet Med, 35(1), 81-85
  15. Kevin AH (2002): Veterinary oncology: the practical veterinarian. Butterworth-Heinemann, Elsevier, USA
  16. Liao KW, Lin ZY, Pao HN, et al (2003): Identification of canine transmi