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Journals / Ankara Üniversitesi Veteriner Fakültesi Dergisi / 2020 / Cilt: 67 - Sayı: 1

Comparison of the effects of zinc-silver cream and Nigella sativa oil on wound healing and oxidative stress in the wound model in rats

Çinko-gümüs krem ve çörekotu yağının rat yara modelindeki yara iyileşmesi ve oksidatif stres üzerine etkilerinin karşılaştırılması

Ali KUMANDAŞ
Birkan KARSLI
Aytül KÜRÜM
Miyase ÇINAR
Ertuğrul ELMA
Pages
33–40
Publication Date
2022-10-12
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Differences among groups for blood lipid peroxidation and antioxidant values were determined with respect tobiochemical oxidative stress results (P

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The present study was undertaken to evaluate of Nigella sativa oil (NSO) and zinc-silver cream in a rat model ofwound healing by means of clinical appearance, histopathology, oxidative stress parameters, and biomechanical tests.
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Key Findings & Data:Group 1 served as a control having wound.
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Conclusion & Impact:Differences among groups for blood lipid peroxidation and antioxidant values were determined with respect tobiochemical oxidative stress results (P
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The present study was undertaken to evaluate of Nigella sativa oil (NSO) and zinc-silver cream in a rat model ofwound healing by means of clinical appearance, histopathology, oxidative stress parameters, and biomechanical tests. The rats weredivided into three groups, each having twenty animals. Group 1 served as a control having wound. Other two groups received eitherNS oil or zinc-silver cream in addition to the wound. The study was initiated after the animals rested for 2 weeks for acclimation.Blood samples were collected from 10 randomly selected animals from each group at days 0, 3, 7 and 14 for oxidative stressmeasurements. Differences among groups for blood lipid peroxidation and antioxidant values were determined with respect tobiochemical oxidative stress results (P

Özet

Bu çalışma, rat yara modelinde çörekotu yağı ve çinko gümüş kreminin klinik görünüm, histopatoloji, oksidatif stres parametreleri ve biyomekanik testlerle değerlendirilerek yara iyileşmesi üzerine etkilerinin karşılaştırılması amacıyla yapıldı. Çalışmada kullanılan ratlar, her bir grupta 20 hayvan bulunan üç gruba ayrıldı. Grup 1, kontrol grubu olarak belirlendi. Diğer iki gruba sırasıyla yara oluşturulduktan sonra çörekotu yağı ve çinko-gümüş krem uygulandı. Çalışma, hayvanların adaptasyonu için 2 hafta dinlendirilmesinden sonra başlatıldı. Oksidatif stres ölçümleri için 0, 3, 7 ve 14. günlerde her gruptan rastgele seçilen 10 hayvandan kan örnekleri alındı. Kan lipid peroksidasyonu ve antioksidan değerleri için gruplar arası farklılıklar biyokimyasal oksidatif stres sonuçlarına göre belirlendi (P

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Cite This Article

KUMANDAŞ, A., KARSLI, B., KÜRÜM, A., ÇINAR, M., ELMA, E. (2022). Comparison of the effects of zinc-silver cream and Nigella sativa oil on wound healing and oxidative stress in the wound model in rats. Ankara Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 67 - Sayı: 1, 33–40. https://ajindex.com/articles/444490

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