SavedAdd your journal

Journals / Ankara Üniversitesi Veteriner Fakültesi Dergisi / 2020 / Cilt: 67 - Sayı: 2

Determination of serum amyloid A, haptoglobin and hepcidin levels in calves with endemic viral pneumonia

Yaygın viral pnömonili buzağılarda serum amiloid A, haptoglobin ve hepsidin düzeylerinin belirlenmes

Ali Burak DÖRTKARDEŞ
Şima ŞAHİNDURAN
Pages
127–131
Publication Date
2022-10-12
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

According to the results, Bovine herpesvirus type-1 (BHV-1) was positive in 3 calves, Bovine viral diarrhea virus (BVDV) was positive in 3 calves, Bovine respiratory syncytial virus (BRSV) was positive in 1 calf, and Bovine parainfluenza virus type 3 (BPI3) was positive in 1 calf.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The aim of this study was to investigate serum amyloid A, haptoglobin and hepcidin levels in respiratory infectionscaused by various viral agents in calves.
📊
Key Findings & Data:Pneumonia is an infectious or non-infectious disease affecting the lungs of all animals, and during the inflammation, blood levels of acute phase proteins increase rapidly.
💡
Conclusion & Impact:According to the results, Bovine herpesvirus type-1 (BHV-1) was positive in 3 calves, Bovine viral diarrhea virus (BVDV) was positive in 3 calves, Bovine respiratory syncytial virus (BRSV) was positive in 1 calf, and Bovine parainfluenza virus type 3 (BPI3) was positive in 1 calf.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The aim of this study was to investigate serum amyloid A, haptoglobin and hepcidin levels in respiratory infectionscaused by various viral agents in calves. Pneumonia is an infectious or non-infectious disease affecting the lungs of all animals, and during the inflammation, blood levels of acute phase proteins increase rapidly. Hepcidin is a hormone that has many functions and is known as type II acute phase reactant. The blood samples were collected from a total of 20 calves to form the study group. The control group consisted of 10 healthy animals. Sera were analyzed with ELISA for antigen detection. According to the results, Bovine herpesvirus type-1 (BHV-1) was positive in 3 calves, Bovine viral diarrhea virus (BVDV) was positive in 3 calves, Bovine respiratory syncytial virus (BRSV) was positive in 1 calf, and Bovine parainfluenza virus type 3 (BPI3) was positive in 1 calf. Adenovirus infection was detected in 5 animals together with other viruses. Mixed infections were observed in 12 calves. Haptoglobin, serum amyloid A and hepcidin values were measured in sera. According to the results, statistically significant differences were observed between thetwo groups for the haptoglobin (P

Özet

Bu çalışmanın amacı, buzağılarda çeşitli viral etkenlerinin neden olduğu solunum yolu enfeksiyonlarında serum amiloid A, haptoglobin ve hepcidin düzeylerini araştırmaktır. Pnömoni, tüm hayvanların solunum sistemlerini etkileyen, enfektif veya nonenfektif sebeplere bağlı olarak gelişen bir hastalık olup, yangı sırasında akut faz proteinlerinin kandaki değerleri hızla artmaktadır. Hepsidin; birçok fonksiyona sahip olan bir hormon olup aynı zamanda tip II akut faz reaktant olduğu bilinmektedir. Araştırmanın çalışma grubunu oluşturmak için, toplam 20 buzağıdan kan örnekleri alındı. Kontrol grubu ise, sağlıklı 10 hayvandan oluşturuldu. Kan serumları, antijen tespiti için ELISA testi ile tarandı. Elde edilen sonuçlara göre 3 hastada Bovine herpes virüs tip 1 (BHV-1), 3 hastada Bovine viral diarrhea virus (BVDV), 1 hastada Bovine respiratory syncytial virüs (BRSV) ve 1 hastada Bovine parainfluenza virüs tip 3 (BPI3) pozitifti. Adenovirüs enfeksiyonu 5 hayvanda diğer virüslerle birlikte tespit edildi. Oniki hastada miks enfeksiyon saptandı. Haptoglobin, serum amiolid A ve hepsidin değerleri toplanan serum örneklerinde ölçüldü. Sonuç olarak; iki grup arasında, haptoglobin (P

🔖

Cite This Article

DÖRTKARDEŞ, A. B., ŞAHİNDURAN, Ş. (2022). Determination of serum amyloid A, haptoglobin and hepcidin levels in calves with endemic viral pneumonia. Ankara Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 67 - Sayı: 2, 127–131. https://ajindex.com/articles/444485

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Alsemgeest SPM, Kalsbeek HC, Wensing T, et al (1994): Concentrations of serum amyloid-a (SAA) and haptoglobin (Hp) as parameters of inflammatory diseases in cattle. Vet Quart, 16, 21-23
  2. Ames TR (1997): Dairy Calf Pneumonia. The disease andits impact. Vet Clin North Am Food Anim Pract, 13, 379-391
  3. Bryson DG, McNulty MS, McCracken RM (1983): Ultrastructural features of experimental parainfluenza type 3 virus pneumonia in calves. J Comp Pathol, 93, 397-414
  4. Coskun A, Guzelbektes H, Simsek A, et al (2012): Haptoglobin and SAA concentrations and enzyme activities in bronchoalveolar lavage fluids from calves with bronchopneumonia. Revue Méd Vét, 163, 615-620
  5. Coyne DW (2011): Hepcidin: clinical utility as a diagnostic tool and therapeutic target. Kidney Int, 80, 240-244
  6. Eckersall PD, Bell R (2010): Acute phase proteins: Biomarkers of infection and inflammation in veterinary medicine. Vet J, 185, 23-27
  7. Erkilic EE, Erdogan HM, Ogun M, et al (2016): Relationship between hepcidin and oxidant/antioxidant status in calves with suspected neonatal septicemia Vet World, 9, 1238-1241
  8. Falzacappa MVV, Muckenthaler MU (2005): Hepcidin: iron-hormone and anti-microbial peptide. Gene, 364, 37– 44
  9. Fry MM, Liggett JL, Baek SJ (2004): Molecular cloning and expression of canine hepcidin. Vet Clin Path, 33, 223- 227
  10. Joshi V, Gupta VK, Bhanuprakash AG, et al (2018): Haptoglobin and serum amyloid A as putative biomarker candidates of naturally occurring bovine respiratory disease in dairy calves. Microb Pathogenesis, 116, 33-37
  11. Kabu M, Elitok B, Kucukkurt I (2016): Decetion of serum amyloid-A concentration in the calf clinically diagnosed with pneumonia, enteritis and pneumoenterites. Ciência Rural, 46, 293-299
  12. Kabu M, Sayın Z (2016): Concentrations of serum amyloid A, haptoglobin, tumour necrosis factor and interleukin-1 and -6 in Anatolian buffaloes naturally infected with dermatophytosis. Vet Med-Czech, 61, 133-135
  13. Kemna E, Pickkers P, Nemeth E, et al (2005): Timecourse analysis of hepcidin, serum iron, and plasma cytokine levels in humans injected with LPS. Blood, 106, 1864-1866
  14. Krause A, Neitz S, Magert HJ, et al (2000): LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity. FEBS Lett, 480, 147–150
  15. Murata H, Shimada N, Yoshioka M (2004): Current research on acute phase proteins in veterinary diagnosis. Vet J, 168, 28-40
  16. Nemeth E, Valore EV, Territo M, et al (2003): Hepcidin, a put