Journals / Ankara Üniversitesi Veteriner Fakültesi Dergisi / 2020 / Cilt: 67 - Sayı: 2

Investigation of enrofloxacin and ciprofloxacin residues by LC-MS/MS in chicken liver marketed in Afyonkarahisar

Afyonkarahisar'da satışa sunulan tavuk karaciğerlerinde enrofloksasin ve siprofloksasin kalıntılarının LC-MS/MS ile araştırılması

Pages
137–142
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, according to the results of this study, chicken livers marketed in Afyonkarahisar city are safe for public health regarding ENR and CIP residues.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Antibiotic residues can remain in animal source foods, mainly in the liver.
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Key Findings & Data:This study aimed to evaluate ENR and its main metabolite ciprofloxacin (CIP) occurrence in 100 chicken livers marketed Afyonkarahisar, Turkey.
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Conclusion & Impact:In conclusion, according to the results of this study, chicken livers marketed in Afyonkarahisar city are safe for public health regarding ENR and CIP residues.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Antibiotic residues can remain in animal source foods, mainly in the liver. Enrofloxacin (ENR) is a syntheticfluoroquinolone antimicrobial agent which is extensively used to treat bacterial infections in poultry. This study aimed to evaluate ENR and its main metabolite ciprofloxacin (CIP) occurrence in 100 chicken livers marketed Afyonkarahisar, Turkey. Chicken liver sampleswere analyzed by LC-MS/MS method with limits of detection for 1.17 μg/kg (ENR) and 1.24 μg/kg (CIP). ENR and CIP were detected in 39% and in 31% of samples, respectively. However, the total sum of both antibiotic residue levels was found to be far below theestablished maximum residue level (200 μg/kg) in all of chicken liver samples. In conclusion, according to the results of this study, chicken livers marketed in Afyonkarahisar city are safe for public health regarding ENR and CIP residues. Nonetheless, periodicalcontrol of chicken liver is advised due to the high incidence of these antibiotics

Özet

Antibiyotik kalıntıları hayvansal orjinli gıdalarda özellikle karaciğerde bulunabilir. Enrofloksasin (ENR) sentetik bir florokinolon antimikrobiyal ajan olup kanatlılarda bakteriyel enfeksiyonların tedavisinde oldukça yaygın olarak kullanılmaktadır. Bu çalışmada Afyonkarahisar, Türkiye’de satışa sunulan 100 tavuk karaciğerinde ENR ve onun ana metaboliti olan siprofloksasin (CIP) varlığının araştırılması amaçlanmıştır. Tavuk karaciğer örnekleri LC-MS/MS metodu ile analiz edilerek, saptama limitleri ENR için 1,17 μg/kg ve CIP için 1,24 μg/kg olarak belirlenmiştir. ENR ve CIP sırasıyla örneklerin %39 ve %31’inde saptanmıştır. Ancak, tavuk karaciğer numunelerinde her iki antibiyotik kalıntısının toplamı belirlenen maksimum kalıntı düzeyinin (200 μg/kg) oldukça altındadır. Sonuç olarak, Afyonkarahisar ilinde satışa sunulan tavuk karaciğerleri ENR ve CIP kalıntısı bakımından değerlendirildiğinde halk sağlığına risk oluşturmamaktadır. Bununla birlikte, bu antibiyotiklerin yüksek insidensi nedeniyle tavuk karaciğerinin periyodik olarak kontrol edilmesi tavsiye edilmektedir.

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Cite This Article

ARSLAN-ACARÖZ, D., SÖZBİLİR, N. B. (2022). Investigation of enrofloxacin and ciprofloxacin residues by LC-MS/MS in chicken liver marketed in Afyonkarahisar. Ankara Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 67 - Sayı: 2, 137–142. https://ajindex.com/articles/444482

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