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Journals / Ankara Üniversitesi Veteriner Fakültesi Dergisi / 2021 / Cilt: 68 - Sayı: 1

Molecular presence of Felis catus gammaherpesvirus -1in cats with ocular disorders in Turkey

Türkiye'de oküler bozukluğu olan kedilerde Felis catus gammaherpesvirus -1'in moleküler varlığı

Bahattin Taylan KOÇ
Müge AKKARTAL
Pages
53–59
Publication Date
2022-10-12
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Acquired knowledge suggests performing further studies on FcaGHV-1.

📌 3 Key Takeaways

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Objective & Hypothesis:Felis catus gammaherpesvirus-1(FcaGHV-1) is a newly discovered feline virus, and its effects on the health of cats are not certainly known.
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Key Findings & Data:Also, emerging viruses may be responsible for ophthalmic diseases of cats.We aimed to investigate the presence of FcaGHV-1, Feline calicivirus(FCV), Feline herpesvirus -1(FHV-1), Feline immunodeficiency virus(FIV), Feline infectious peritonitis virus(FIPV), Feline leukemia virus(FeLV), Feline panleukopenia virus(FPV) in cats in Turkey by molecular methods, and to examine the relationship between the virus and ocular disorders by obtained data.
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Conclusion & Impact:Acquired knowledge suggests performing further studies on FcaGHV-1.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Felis catus gammaherpesvirus-1(FcaGHV-1) is a newly discovered feline virus, and its effects on the health of cats are not certainly known. Known feline viruses playa huge role in ocular disorders in domestic and wild cats. Also, emerging viruses may be responsible for ophthalmic diseases of cats.We aimed to investigate the presence of FcaGHV-1, Feline calicivirus(FCV), Feline herpesvirus -1(FHV-1), Feline immunodeficiency virus(FIV), Feline infectious peritonitis virus(FIPV), Feline leukemia virus(FeLV), Feline panleukopenia virus(FPV) in cats in Turkey by molecular methods, and to examine the relationship between the virus and ocular disorders by obtained data. Swab, blood and biopsy samples were collected from 45 owned cats with ocular disorders. Molecular techniques including viral genome amplification and sequencing were used in this study. Two out of 45 cats (2/45; 4.4%) found to be FcaGHV-1 and FIV positive.Our two sequences and a reference sequence from Japan (LC437925) have constructed a separated subgroup in the molecular phylogenetic tree. In this study, we have not found a closerelationship between ocular disorders and the presence ofFcaGHV-1. Thisis the first study exhibiting the presence of FcaGHV-1 and its molecular status in Turkey. Acquired knowledge suggests performing further studies on FcaGHV-1.

Özet

Felis catus gammaherpesvirus-1(FcaGHV-1), kedilerin sağlığı üzerindeki etkileri bilinmeyen yeni keşfedilmiş bir kedi virusudur. Bilinen kedi virusları, evcil ve vahşi kedilerdeki oküler bozukluklarda büyük rol oynamaktadırlar. Ayrıca, yeni ortaya çıkan viruslar kedilerin oftalmik hastalıklarından sorumlu olabilir. Bu nedenle hem Türk kedilerinde FcaGHV-1, Feline calicivirus(FCV), Feline herpesvirus -1(FHV-1), Feline immunodeficiency virus(FIV), Feline infectious peritonitis virus(FIPV), Feline leukemia virus(FeLV), Feline panleukopenia virus(FPV) varlığını moleküler yöntemlerle araştırmayı, hem de virus ve oküler bozukluklar arasındaki ilişkiyi elde edilen verilerle incelemeyi amaçladık. Swap, kan ve biyopsi örnekleri, oküler bozukluğu olan 45 kediden toplandı. Bu çalışmada viral genom amplifikasyonu ve sekanslama dahil moleküler teknikler kullanılmıştır. 45 kediden ikisinde (2/45; %4,4) FcaGHV-1 veFIV pozitif olarak bulundu. İki sekansımız ve Japonya'dan bir referans sekans (LC437925), moleküler filogenetik ağaçta ayrı bir alt grup oluşturmuştur. Bu çalışmada, oküler bozukluklar ile FcaGHV-1 arasında sıkı bir ilişki saptanmamıştır. Bu, Türkiye'de FcaGHV-1 varlığını ve moleküler durumunu gösteren ilk çalışmadır. Edinilen bilgi, FcaGHV-1 hakkında daha fazla çalışma yapılmasını önermektedir.

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Cite This Article

KOÇ, B. T., AKKARTAL, M. (2022). Molecular presence of Felis catus gammaherpesvirus -1in cats with ocular disorders in Turkey. Ankara Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 68 - Sayı: 1, 53–59. https://ajindex.com/articles/444444

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