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Journals / Ankara Üniversitesi Veteriner Fakültesi Dergisi / 2022 / Cilt: 69 - Sayı: 1

High mortality rate of shipping fever cases in cattle caused by bovine herpesvirus type 1 (BoHV-1)

Bovine herpesvirus tip 1’in (BoHV-1) neden olduğu yüksek ölüm oranlı nakil hastalığı vakaları

Kadir YEŞİLBAĞ
Özer ATEŞ
Berfin KADİROĞLU
Gizem AYTOĞU
Pages
69–75
Publication Date
2022-10-12
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These results showed a high mortality risk for imported animals and the possibility for BoHV-1 entering the receiving country via imported animals after transport.

📌 3 Key Takeaways

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Objective & Hypothesis:This study reports the high prevalence and molecular characterization of BoHV-1 infection in imported cattle with respiratory system disease after international transport.
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Key Findings & Data:A high mortality rate of 14.16% (51/360) was reported in a group of animals imported from Hungary to Turkey in 2019.
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Conclusion & Impact:These results showed a high mortality risk for imported animals and the possibility for BoHV-1 entering the receiving country via imported animals after transport.
🔬Design:Research Article
📍Scope:2019 · 17 samples
⚙️Variables:Domain Parameters

Abstract

This study reports the high prevalence and molecular characterization of BoHV-1 infection in imported cattle with respiratory system disease after international transport. A high mortality rate of 14.16% (51/360) was reported in a group of animals imported from Hungary to Turkey in 2019. A total of 17 samples were evaluated (3 lung tissue and 14 nasal swab samples) from 15 cattle aged 6 to 9 months not vaccinated against BoHV-1. Virus isolation, polymerase chain reaction (PCR) and restriction endonuclease analysis (REA) procedures were performed within the scope of this study. By virus isolation in MDBK cells, cytopathologic effects was detected in 8 samples (3 lung tissue and 5 nasal swabs samples). The same eight samples were also found positive by BoHV-1 PCR targeting gC (UL44) gene region. According to the sequencing result, the sample (ID: 10054) dropped into a cluster of BoHV-1.1. The REA was applied to the samples to confirm the results of phylogenetic analysis. All of the isolates were identified in the subgroup BoHV-1.1 by REA. These results showed a high mortality risk for imported animals and the possibility for BoHV-1 entering the receiving country via imported animals after transport. This event is a serious problem both for the control of BoHV-1 as well as for animal health and welfare

Özet

Bu çalışmada, uluslararası nakil sonrası solunum sistemi hastalığı tespit edilen ithal sığırlarda BoHV-1 enfeksiyonunun yüksek prevalansını ve etkenin moleküler karakterizasyonunun bildirilmesi amaçlanmıştır. 2019 yılında Macaristan'dan Türkiye'ye ithal edilen bir grup sığırda yüksek ölüm oranı (%14,16; 51/360) tespit edildi. 6-9 ay yaş aralığında ve BoHV-1’e karşı aşılanmamış 15 hayvandan sağlanan toplam 17 örnek (3 akciğer dokusu ve 14 burun svabı) değerlendirildi. Çalışma kapsamında virus izolasyonu, PCR ve restriksiyon endonükleaz analizi (REA) işlemleri uygulandı. MDBK hücrelerindeki virus izolasyonu çalışması sonucunda 8 örnekte (3 akciğer dokusu ve 5 burun svabı) sitopatolojik etki tespit edildi. BoHV-1’in gC (UL44) gen bölgesini hedefleyen PCR metodu aracılığıyla aynı 8 örnekte pozitif sonuç alındı. Nükleik asit dizi analizi için seçilen 1 izolatın (ID: 10054) filogeni analizinde BoHV-1.1 alt tipinde yer aldığı tespit edildi. Filogenetik analiz sonuçlarını doğrulamak için numunelere REA uygulandı ve tüm izolatların BoHV-1.1 alttipi içerisinde yer aldığı teyit edildi. Bu sonuçlar, nakliye sonrasında ithal hayvanlarda BoHV-1 kaynaklı yüksek mortalite oranının görülebileceğini ve uluslararası hayvan ticaretinde uygulanan tüm test protokollerine rağmen BoHV-1'in ithal hayvanlar aracılığıyla yeni bölgelere rahatlıkla taşınabileceğini göstermektedir. Bu durum hem BoHV-1'in kontrolü hem de hayvan sağlığı ve refahı için ciddi bir sorun teşkil etmektedir.

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Cite This Article

YEŞİLBAĞ, K., ATEŞ, Ö., KADİROĞLU, B., AYTOĞU, G. (2022). High mortality rate of shipping fever cases in cattle caused by bovine herpesvirus type 1 (BoHV-1). Ankara Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 69 - Sayı: 1, 69–75. https://ajindex.com/articles/444381

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