Journals / Ankara Üniversitesi Tıp Fakültesi Mecmuası / 2019 / Cilt: 72 - Sayı: 2

Are Plasma Neutrophil Gelatinase Associated Lipocalin Levels Diagnostic in Uncomplicated Urinary Tract Infections?

Plazma Nötrofil Jelatinaz İlişkili Lipocalin Düzeyleri Komplike Olmayan İdrar Yolu Enfeksiyonunda Tanısal mıdır?

Pages
235–240
Publication Date
2022-10-10
DOI
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⚡ TL;DR(Too Long; Didn't Read)

All of the patients had their leukocyte, neutrophil,C-reactive protein (CRP), erythrocyte sedimentation rate, and NGAL levels evaluated before and after the treatment, and correlation among theseparameters were investigated.Results: In the study group, the plasma leukocyte, neutrophil, and CRP levels before the treatment were significantly higher compared to the aftertreatmentperiod (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Acute uncomplicated lower urinary tract infections are among the most common causes for emergency department visits and empiricalantibiotic prescriptions.
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Key Findings & Data:The purpose of this study was to determine whether the serum levels of the neutrophil gelatinase associated lipocalin(NGAL) molecule were important in the diagnosis and follow-up of non-complicated lower urinary tract infections.Materials and Methods: This was a cross-sectional, prospective study conducted from September 15, 2013 to April 15, 2014 in an academicemergency department.
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Conclusion & Impact:All of the patients had their leukocyte, neutrophil,C-reactive protein (CRP), erythrocyte sedimentation rate, and NGAL levels evaluated before and after the treatment, and correlation among theseparameters were investigated.Results: In the study group, the plasma leukocyte, neutrophil, and CRP levels before the treatment were significantly higher compared to the aftertreatmentperiod (p
🔬Design:Research Article
📍Scope:2013 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: Acute uncomplicated lower urinary tract infections are among the most common causes for emergency department visits and empiricalantibiotic prescriptions. The purpose of this study was to determine whether the serum levels of the neutrophil gelatinase associated lipocalin(NGAL) molecule were important in the diagnosis and follow-up of non-complicated lower urinary tract infections.Materials and Methods: This was a cross-sectional, prospective study conducted from September 15, 2013 to April 15, 2014 in an academicemergency department. Eighty patients were enrolled in the study group and 40 healthy subjects in the control group. The patients had acuteuncomplicated lower urinary tract infections with pyuria detected in a complete urinary test. All of the patients had their leukocyte, neutrophil,C-reactive protein (CRP), erythrocyte sedimentation rate, and NGAL levels evaluated before and after the treatment, and correlation among theseparameters were investigated.Results: In the study group, the plasma leukocyte, neutrophil, and CRP levels before the treatment were significantly higher compared to the aftertreatmentperiod (p

Özet

Amaç: Akut komplike olmayan alt üriner sistem enfeksiyonları acil servislerde sıklıkla karşılaşılan ve ampirik antibiyotik reçete edilen hastalıklardandır. Bu çalışmada nötrofil jelatinaz ilişkili lipokalin (NGAL) molekülünün serum düzeylerinin akut komplike olmayan idrar yolu enfeksiyonlarının tanı ve takibinde öneminin olup olmadığının ortaya konması amaçlandı. Gereç ve Yöntem: Bu çalışma prospektif kesitsel bir çalışma olup 15 Eylül 2013-15 Nisan 2014 tarihinde yapıldı. Bu çalışmaya akut komplike olmayan alt üriner sistem enfeksiyonu semptomları olan, tam idrar tetkikinde piyüri saptanan ve ampirik antibiyotik tedavisi acil serviste planlanan 18-65 yaş arası 80 hasta ve kontrol grubu olarak sağlıklı 40 kişi dahil edildi. Tüm hastalardan tedavi öncesinde ve sonrasında lökosit, nötrofil, C-reaktif protein (CRP), eritrosit sedimentasyon hızı ve NGAL ölçümü yapıldı ve aralarındaki korelasyon araştırıldı. Bulgular: Hasta grubunda, plazma lökosit, nötrofil ve CRP’ye ait tedavi öncesi değerlerin tedavi sonrası değerlerine oranla daha yüksek olduğu görüldü (p

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Cite This Article

OĞUZ, A. B., GÜLÜNAY, B., EKŞİOĞLU, M., GÜNALP, M., DEMİRKAN, A., POLAT, O. (2022). Are Plasma Neutrophil Gelatinase Associated Lipocalin Levels Diagnostic in Uncomplicated Urinary Tract Infections?. Ankara Üniversitesi Tıp Fakültesi Mecmuası, Cilt: 72 - Sayı: 2, 235–240. https://ajindex.com/articles/443593

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