Journals / Ankara Üniversitesi Tıp Fakültesi Mecmuası / 2020 / Cilt: 73 - Sayı: 2

Evaluation of Gastrointestinal and Hepatological Problems in Obese Patients Evaluated in the Pediatric Gastroenterology Clinic with the Diagnosis of Hepatosteatosis

Hepatosteatoz Tanısı ile Çocuk Gastroenteroloji Kliniğinde Değerlendirilen Obez Hastalarda Gastrointestinal ve Hepatolojik Sorunların Değerlendirilmesi

Pages
130–134
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In these patients, pediatric gastroenterology follow-up is absolutely necessary for multidisciplinary obesity management.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: There are many gastrointestinal (GI) and hepatic diseases for which obesity is the direct cause (eg, nonalcoholic fatty liver disease) or is a significant risk factor, such as reflux esophagitis and gallstones.
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Key Findings & Data:Materials and Methods: This study was retrospectively conducted in 201 pediatric patients who were diagnosed with obesity [body mass index (BMI) ≥95%] and hepatosteatosis between January and December 2018.
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Conclusion & Impact:In these patients, pediatric gastroenterology follow-up is absolutely necessary for multidisciplinary obesity management.
🔬Design:Research Article
📍Scope:2018 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: There are many gastrointestinal (GI) and hepatic diseases for which obesity is the direct cause (eg, nonalcoholic fatty liver disease) or is a significant risk factor, such as reflux esophagitis and gallstones. In our study; we aimed to investigate the incidence of GI diseases in pediatric patients with obesity and hepatosteatosis and to evaluate the efficacy of diagnostic investigations for etiology in patients with hepatosteatosis and/or elevated transaminases. Materials and Methods: This study was retrospectively conducted in 201 pediatric patients who were diagnosed with obesity [body mass index (BMI) ≥95%] and hepatosteatosis between January and December 2018. Results: A total of 201 [55.2% (n=111) male] patients with a mean age of 12.9±3.4 years were included in the study. The mean BMI of the patients was 29.8 and the BMI standard deviation score was 2.69. Twenty-three (11.4%) of the patients had gastro esophageal reflux disease, 23 (11.4%) had constipation and 13 (6.5%) had functional abdominal pain and/or irritable bowel syndrome and 13 (6.5%) had symptoms compatible with gastritis. One of the patients with hepatosteatosis and elevated transaminases was diagnosed with autoimmune hepatitis and the other was diagnosed with alpha-1 antitrypsin deficiency. Conclusion: Consequently, obesity and obesity-related morbidities, which are increasing in the world and in our country, are an important health problem since childhood. GI diseases are quite common in obese patients. Other treatable causes of liver diseases should be evaluated in the followup of obese patients. In these patients, pediatric gastroenterology follow-up is absolutely necessary for multidisciplinary obesity management.

Özet

Amaç: Obezitenin doğrudan neden olduğu alkole bağlı olmayan yağlı karaciğer hastalığı (NAYKH) veya reflü özofajiti ve safra kesesi taşları gibiönemli bir risk faktörü olduğu birçok gastrointestinal (GI) ve hepatolojik hastalık vardır. Bu çalışmada; çocuk gastroenteroloji kliniğine başvuran,obezite ve hepatosteatozu olan çocuk hastalarda GI hastalıkların sıklığının araştırılması ve hepatosteatoz ve/veya transaminaz yüksekliği olanhastalarda kronik karaciğer hastalığı etiyolojisine yönelik yapılan tanısal tetkiklerin verimliliğinin değerlendirilmesi amaçlanmıştır.Gereç ve Yöntem: Bu çalışma; Ocak - Aralık 2018 tarihleri arasında Sağlık Bilimleri Üniversitesi, Keçiören Eğitim ve Araştırma Hastanesi ÇocukGastroenteroloji Polikliniği’nde, obezite [vücut kitle indeksi (VKİ) ≥%95] ve hepatosteatoz tanılarıyla değerlendirilen 201 çocuk hastaya ait tıbbiverilerin geriye yönelik olarak taranmasıyla gerçekleştirilen bir çalışmadır.Bulgular: Yaş ortalaması 12,9±3,4 yıl olan 201 [%55,2’si (n=111) erkek] hasta çalışmaya dahil edilmiştir. Hastaların VKİ ortalaması 29,8, VKİ standartsapma skoru 2,69’du. Hastaların 23’ünün (%11,4) gastro özofajial reflü hastalığı, 23’ünün (%11,4) kabızlık, 13’ünün (%6,5) fonksiyonel karın ağrısıve/veya huzursuz bağırsak sendromu ve 13’ünün (%6,5) ise gastrit ile uyumlu yakınmaları vardı. Hepatosteatozu ve transaminaz yüksekliği olanhastalardan birine otoimmün hepatit bir diğerine de alfa-1 antitripsin eksikliği tanısı koyuldu.Sonuç: Sonuç olarak dünyada ve ülkemizde giderek artan sıklıkta görülen obezite ve obeziteye bağlı morbiditeler çocukluk yaş grubundan itibarenönemli bir sağlık sorunudur. Obez hastalarda GI hastalıklar oldukça sık görülmektedir. Obez hastaların takiplerinde tedavi edilebilir diğer karaciğerhastalıkları nedenleri de değerlendirilmelidir. Bu hastalarda multidisipliner obezite yönetimi açısından çocuk gastroenteroloji takibi mutlakagerekmektedir.

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Cite This Article

SELBUZ, S. (2022). Evaluation of Gastrointestinal and Hepatological Problems in Obese Patients Evaluated in the Pediatric Gastroenterology Clinic with the Diagnosis of Hepatosteatosis. Ankara Üniversitesi Tıp Fakültesi Mecmuası, Cilt: 73 - Sayı: 2, 130–134. https://ajindex.com/articles/443526

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