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Journals / Ankara Üniversitesi Tıp Fakültesi Mecmuası / 2021 / Cilt: 74 - Sayı: 3

Efficacy of Prognostic Scoring Systems and Neutrophil-to- Lymphocyte Ratio (NLR) Among Critically Ill Elder Sepsis Patients

Yaşlı Sepsis Hastalarında Prognostik Puanlama Sistemlerinin ve Nötrofil-Lenfosit Oranının (NLO) Etkinliği

Bilgin Bahadır BAŞGÖZ
Musa Barış AYKAN
Ramazan ACAR
İlker TAŞÇI
Pages
289–295
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: Overall, the data of 36 patients were analyzed (mean age: 80.00±6.37 years, female: 58.3%).

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Several scoring models and biomarkers are available to predict survival among critically ill patients.
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Key Findings & Data:By the end of a 28-day follow-up period, survivors and non-survivors were compared for the study parameters.
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Conclusion & Impact:Results: Overall, the data of 36 patients were analyzed (mean age: 80.00±6.37 years, female: 58.3%).
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: Several scoring models and biomarkers are available to predict survival among critically ill patients. However, their accuracy among older adults with sepsis has been questioned. In this study, we aimed to evaluate the currently used prognostic scoring scales and neutrophil-to- lymphocyte ratio (NLR) in the prediction of survival among older adults with sepsis. Materials and Methods: The study prospectively included older adults who were admitted to the intensive care unit (ICU) with sepsis. On admission, Acute Physiology And Chronic Health Evaluation (APACHE)-II, Sequential (sepsis-related) Organ Failure Assessment (SOFA), Glasgow coma scale (GCS) score, and NLR were calculated. By the end of a 28-day follow-up period, survivors and non-survivors were compared for the study parameters. Results: Overall, the data of 36 patients were analyzed (mean age: 80.00±6.37 years, female: 58.3%). The rate of mortality was 47.3% (n=17). The mean SOFA score and the median NLR on admission were significantly lower in survivors [SOFA: 10.37±2.91, and NLR: 9.64 (11.25)] vs non-survivors [SOFA: 12.82±3.21 and NLR: 14.95 (35.53)] (p

Özet

Amaç: Yoğun bakım hastalarında mortaliteyi tahmin eden birçok puanlama sistemi ve biyobelirteç mevcuttur. Ancak yaşlı sepsis hastalarında kullanılabilirlikleri konusunda netlik bulunmamaktadır. Bu çalışmada, yaşlı sepsis hastalarında sağkalımı öngörmede şu anda kullanılan prognostik skorlama ölçeklerini ve nötrofil lenfosit oranını (NLO) değerlendirmeyi amaçladık. Gereç ve Yöntem: Çalışmaya yoğun bakım ünitesine sepsis tanısı ile yatırılan yaşlı hastalar prospektif olarak dahil edildi. Başvuru anında Akut Fizyoloji ve Kronik Sağlık Değerlendirmesi-II (APACHE), Sıralı (sepsisle ilişkili) Organ Yetmezliği Değerlendirmesi (SOFA) ve Glasgow koma skoru (GKS) puanı ve NLO hesaplandı. 28 günlük bir takip süresinin sonunda, hastalar “hayatta kalanlar” ve “hayatta kalmayanlar” olarak iki gruba ayrıldı ve çalışma parametreleri yönünden karşılaştırıldı. Bulgular: Otuz altı hastanın verileri analiz edildi (ortalama yaş: 80,00±6,37 yıl, kadın: %58,3). Ölüm oranı %47,3 (n=17) idi. Başvuru anındaki ortalama SOFA skoru ve medyan NLO, hayatta kalanlarda [SOFA: 10,37±2,91 ve NLR: 9,64 (11,25)], hayatta kalmayanlara [SOFA: 12,82±3,21 ve NLR: 14,95 (35,53)] (p

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Cite This Article

BAŞGÖZ, B. B., AYKAN, M. B., ACAR, R., TAŞÇI, İ. (2022). Efficacy of Prognostic Scoring Systems and Neutrophil-to- Lymphocyte Ratio (NLR) Among Critically Ill Elder Sepsis Patients. Ankara Üniversitesi Tıp Fakültesi Mecmuası, Cilt: 74 - Sayı: 3, 289–295. https://ajindex.com/articles/443445

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