SavedAdd your journal

Journals / Ankara Medical Journal / 2018 / Cilt: 18 - Sayı: 3

The Ultrasonographical Features and Cytological Findings of Thyroid Nodules in Patients with Hashimoto Thyroiditis

Hashimoto Tiroditine Eşlik Eden Nodüllerin Ultrasonografik Özellikleri ve Sitolojik Bulguları

Hüsniye BAŞER
Didem ÖZDEMİR
Bekir ÇAKIR
Şeyda TÜRKÖLMEZ
Fatma Dilek DELLAL
Aylin KILIÇ YAZGAN
Reyhan ERSOY
Pages
438–446
Publication Date
2022-10-12
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Antibody positivity and hypothyroidism were higher in patients wtih HT (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: It is unclear whether ultrasonography (US) features and fine‐needle aspiration biopsy (FNAB) results of nodules accompanying with Hashimoto’s thyroiditis (HT) are affected by the presence of thyroiditis or not.
📊
Key Findings & Data:Materials and Methods: Patients who underwent thyroid FNAB in our clinic during a 4 months’ period were evaluated prospectively.
💡
Conclusion & Impact:Antibody positivity and hypothyroidism were higher in patients wtih HT (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: It is unclear whether ultrasonography (US) features and fine‐needle aspiration biopsy (FNAB) results of nodules accompanying with Hashimoto’s thyroiditis (HT) are affected by the presence of thyroiditis or not. In this study, we aimed to compare US features and cytological results of nodules in patients with and without HT. Materials and Methods: Patients who underwent thyroid FNAB in our clinic during a 4 months’ period were evaluated prospectively. Informed consent was obtained from all patients and US features of nodules were determined. Cytological results were classified as nondiagnostic, benign, atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS), follicular neoplasia/suspicious for follicular neoplasia (FN/SFN), suspicious for malignancy and malignant. Results: 181 (35.49%) patients with HT (166 female, 15 male) and 329 (64.51%) patients (277 female and 52 male) without HT were included. The mean age of patients with HT was significantly higher than patients without HT (50.62±12.28 vs 46.73±12.04, p=0.001). Antibody positivity and hypothyroidism were higher in patients wtih HT (p

Özet

Amaç: Hashimoto tiroiditi (HT) olan hastalarda tiroid nodüllerin ultrasonografik özellikleri ve ince iğneaspirasyon biyopsisi (İİAB) sonuçlarının tiroidit varlığından etkilenip etkilenmediği net olarakbilinmemektedir. Bu çalışmada HT’ye eşlik eden nodüllerin ultrasonografik özelliklerinin ve sitolojikbulgularının HT olmayan nodüler guatrlı hastalarla karşılaştırılması amaçlanmıştır.Materyal ve Metot: Kliniğimizde 4 ay süresince ultrason (US) eşliğinde tiroid İİAB yapılan hastalarprospektif olarak incelendi. Tüm hastalardan bilgilendirilmiş olur formu alındı ve İİAB yapılacak olannodüllerin ultrasonografik özellikleri belirlendi. Sitolojik olarak nodüller Bethesda sınıflamasına göreyetersiz, benign, önemi belirsiz atipi/önemi belirsiz foliküler lezyon (ÖBA/ÖBFL), folikülerneoplazi/foliküler neoplazi şüphesi (FN/FNŞ), malinite şüphesi ve malign olmak üzere 6 gruba ayrıldı.Bulgular: Çalışmaya 181 (%35,49) HT olan (166 kadın, 15 erkek) ve 329 (%64,51) HT olmayan (277 kadın,52 erkek) 510 hasta alındı. HT olanların yaş ortalaması, olmayanlara oranla daha fazlaydı (sırasıyla50,62±12,28 ve 46,73±12,04, p=0,001). HT’li hastalarda antikor pozitifliği ve hipotiroidi, HTolmayanlardan anlamlı derecede yüksekti (p

🔖

Cite This Article

BAŞER, H., ÖZDEMİR, D., ÇAKIR, B., TÜRKÖLMEZ, Ş., DELLAL, F. D., YAZGAN, A. K., ERSOY, R. (2022). The Ultrasonographical Features and Cytological Findings of Thyroid Nodules in Patients with Hashimoto Thyroiditis. Ankara Medical Journal, Cilt: 18 - Sayı: 3, 438–446. https://ajindex.com/articles/441970

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Caturegli P, De Remigis A, Rose NR. Hashimoto thyroiditis: clinical and diagnostic criteria. Autoimmun Rev 2014;13(4‐5):391‐7
  2. Langer JE, Khan A, Nisenbaum HL, et al. Sonographic appearance of focal thyroiditis. AJR Am J Roentgenol 2001;176(3):751‐4
  3. Cappelli C, Castellano M, Pirola I, et al. The predictive value of ultrasound findings in the management of thyroid nodules. QJM 2007;100(1):29‐35
  4. Moon WJ, Jung SL, Lee JH, et al; and Thyroid Study Group, Korean Society of Neuro‐ and Head and Neck Radiology. Benign and malignant thyroid nodules: US differentiation–multicenter retrospective study. Radiology 2008;247(3):762–70
  5. Takashima S, Matsuzuka F, Nagareda T, Tomiyama N, Kozuka T. Thyroid nodules associated with Hashimoto thyroiditis: assessment with US. Radiology. 1992;185(1):125‐30
  6. Isik S, Gokay F, Ozuguz U, et al. Comparison of the prevalence and sonographic features of thyroid nodules accompanying autoimmune thyroid diseases. Endokrynol Pol 2010;61(6):658‐64
  7. Mukasa K, Noh JY, Kunii Y, et al. Prevalence of malignant tumors and adenomatous lesions detected by ultrasonographic screening in patients with autoimmune thyroid diseases. Thyroid 2011;21(1):37‐41
  8. Cibas ES, Ali SZ. The Bethesda system for reporting thyroid cytopathology. Thyroid 2008;19:1159‐ 1165
  9. Theoharis CG, Schofield KM, Hammers L, Udelsman R, Chhieng DC. The Bethesda thyroid fine needle aspiration classification system: year 1 at an academic institution. Thyroid 2009;19:1215‐ 23
  10. Luu MH, Fischer AH, Pisharodi L, Owens CL. Improved preoperative definitive diagnosis of papillary thyroid carcinoma in FNAs prepared with both ThinPrep and conventional smears compared with FNAs prepared with ThinPrep alone. Cancer Cytopathol 2011;119:68‐73
  11. Bongiovanni M, Spitale A, Faquin WC, Mazzucchelli L, Baloch ZW. The Bethesda System for Reporting Thyroid Cytopathology: a meta‐analysis. Acta Cytol 2012;56:333‐9
  12. Cunha LL, Ferreira RC, Marcello MA, Vassallo J, Ward LS. Clinical and pathological implications of concurrent autoimmune thyroid disorders and papillary thyroid cancer. J Thyroid Res 2011;2011:387062
  13. Azizi G, Malchoff CD. Autoimmune thyroid disease: a risk factor for thyroid cancer. Endocr Pract. 2011;17(2):201‐9
  14. Kim KW, Park YJ, Kim EH, et al. Elevated risk of papillary thyroid cancer in Korean patients with Hashimoto's thyroiditis. Head Neck 2011;33(5):691‐5
  15. Zhang L, Li H, Ji QH, et al. The clinical features of papillary thyroid cancer in H