Journals / Ankara Medical Journal / 2019 / Cilt: 19 - Sayı: 2

Investigation of Vitamin D Levels and Metabolic Parameters in Patients With Subclinical Hyperthyroidism

Subklinik Hipertiroidili Hastalarda Vitamin D Düzeyinin ve Metabolik Parametrelerin İncelenmesi

Pages
261–269
Publication Date
2022-10-12
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

Materials and Methods: A total of 128 subjects were included in the study between April 2017 and April 2018 which are 39 patients with subclinical hyperthyroidism diagnosed with toxic adenoma, toxic multinodular goiter (TMNG), toxic diffuse goiter (TDG) and 35 subject 1≤TSH

📌 3 Key Takeaways

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Objective & Hypothesis:Abstract Objectives: Subclinical hyperthyroidism is a major health problem that is common in the population and requires long‐term follow‐up due to various complications including atrial fibrillation and osteoporosis.
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Key Findings & Data:In recent years, vitamin D has been investigated in the pathogenesis of autoimmune diseases including endocrine system beside well known skeletal effects.
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Conclusion & Impact:Materials and Methods: A total of 128 subjects were included in the study between April 2017 and April 2018 which are 39 patients with subclinical hyperthyroidism diagnosed with toxic adenoma, toxic multinodular goiter (TMNG), toxic diffuse goiter (TDG) and 35 subject 1≤TSH
🔬Design:Research Article
📍Scope:2017 Verileri
⚙️Variables:Domain Parameters

Abstract

Abstract Objectives: Subclinical hyperthyroidism is a major health problem that is common in the population and requires long‐term follow‐up due to various complications including atrial fibrillation and osteoporosis. In recent years, vitamin D has been investigated in the pathogenesis of autoimmune diseases including endocrine system beside well known skeletal effects. The aim of this study is to investigate vitamin D levels, metabolic parameters and the relationship between these parameters and vitamin D and TSH levels in patients with subclinical hyperthyroidism. Materials and Methods: A total of 128 subjects were included in the study between April 2017 and April 2018 which are 39 patients with subclinical hyperthyroidism diagnosed with toxic adenoma, toxic multinodular goiter (TMNG), toxic diffuse goiter (TDG) and 35 subject 1≤TSH

Özet

Amaç: Subklinik hipertiroidi toplumda oldukca sık görülen, atriyal fibrilasyon ve osteoporoz gibi çeşitlikomplikasyonlar nedeni ile uzun süreli takip gereken önemli bir sağlık problemidir. Vitamin D iseendokrin sistemi de kapsayan otoimmün hastalıkların patogenezindeki yeri, son yıllarda daha çokaraştırılmaktadır. Çalışmamızda, subklinik hipertiroidili hastalarda vitamin D düzeylerini ve çeşitlibiyokimyasal parametreleri incelemeyi amaçladık. Ayrıca vitamin D ile biyokimyasal parametreler vetiroid fonksiyon testleri arasındaki ilişkiyi inceledik.Materyal ve Metot: Nisan 2017‐Nisan 2018 tarihleri arasında endokrinoloji polikliniğine başvuran vesubklinik hipertiroidi tanısı almış; toksik adenom, toksik multinodüler guatr (TMNG), toksik diffuzguatr (TDG) tanılı 39 hasta ile 89 sağlıklı kontrol grubu dahil edildi. Kontrol grubu ayrıca TSH düzeyleri1≤TSH

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Cite This Article

KESKİN, M., ADEMOĞLU, E., KOCA, A. O., ERTUĞRUL, D. T. (2022). Investigation of Vitamin D Levels and Metabolic Parameters in Patients With Subclinical Hyperthyroidism. Ankara Medical Journal, Cilt: 19 - Sayı: 2, 261–269. https://ajindex.com/articles/441876

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References (15)

  1. Biondi, Cooper. Subclinical Hyperthyroidism. N Engl J Med. 2018 Oct 11;379(15):1485‐6
  2. Kim YA, Park YJ. Prevalence and risk factors of subclinical thyroid disease. Endocrinol Metab (Seoul). 2014 Mar;29(1):20‐9
  3. Demet Yavuz D,Mete T, Yavuz R, Altunoğlu A. D Vitamini, Kalsiyum ve Mineral Metabolizması, D Vitaminin İskelet Dışı Etkileri ve Kronik Böbrek Yetmezliğinde Nutrisyonel D Vitamini Kullanımı. Ankara Med J, 2014, 14(4): 162‐71
  4. Dilekçi E, Dilekçi EA, Demirkol ME, Öğün MN. Evde sağlık hastalarında D vitamin düzeyleri. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi 2018; 20 (2):101‐5
  5. Kim D. The role of vitamin D in thyroid diseases. Int.J. Mol. Sci. 2017;18,1949
  6. Velentzas GC. Some observations on vitamin D3 metabolism in thyrotoxicosis. Acta Vitaminol Enzymol. 1983; 5(3):159‐63 7. Das G, Ojewuyi TA, Baglioni P, Geen J, Premawardhana LD, Okosieme OE. Serum thyrotrophin at baseline predicts the natural course of subclinical hyperthyroidism. Clin Endocrinol (Oxf ). 2012 Jul;77(1):146‐51
  7. De Leo S, Lee SY, Braverman LE. Hyperthyroidism. Lancet. 2016 Aug 27;388(10047):906‐18
  8. Lillevang‐Johansen M, Abrahamsen B, Jørgensen HL, Brix TH, Hegedüs L. Excess Mortality in Treated and Untreated Hyperthyroidism Is Related to Cumulative Periods of Low Serum TSH. J Clin Endocrinol Metab. 2017 Jul 1;102(7):2301‐9
  9. Muscogiuri G, Bhattoa HP. Vitamin D and endocrine disorders: routine laboratory diagnostic implications. EJIFCC. 2018 Jul 11;29(2):111‐6
  10. Ma J, Wu D, Li C, Fan C, Chao N, Liu J, Li Y, Wang R, Miao W, Guan H, Shan Z, Teng W. Lower Serum 25‐Hydroxyvitamin D Level is Associated With 3 Types of Autoimmune Thyroid Diseases. Medicine (Baltimore). 2015 Sep;94(39):e1639
  11. Vondra K, Stárka L, Hampl R. Vitamin D and thyroid diseases. Physiol Res. 2015;64 Suppl 2:S95‐ S100
  12. Mangaraj S, Choudhury AK, Swain BM, Sarangi PK, Mohanty BK, Baliarsinha AK. Evaluation of Vitamin D Status and its Impact on Thyroid Related Parameters in New Onset Graves' Disease‐ A Cross‐sectional Observational Study. Indian J Endocrinol Metab. 2019 Jan‐Feb;23(1):35‐9
  13. Ke W, Sun T, Zhang Y, He L, Wu Q, Liu J, Zha B. 25‐Hydroxyvitamin D serum level in Hashimoto's thyroiditis, but not Graves' disease is relatively deficient. Endocr J. 2017 Jun 29;64(6):581‐7
  14. Zhang H, Liang L, Xie Z. Low Vitamin D Status is Associated with Increased Thyrotropin‐ Receptor Antibody Titer in Graves Disease. Endocr Pract. 2015 Mar;21(3):258‐63
  15. Yasuda T, Okamoto Y, Hamada