Journals / Ankara Medical Journal / 2020 / Cilt: 20 - Sayı: 1

EVALUATION OF SOCIODEMOGRAPHIC DATA, BREAST DENSITY, PRESENCE OF MENOPAUSE AND HEMATOLOGICAL AND HISTOPATHOLOGICAL FINDINGS IN WOMEN DIAGNOSED WITH BREAST CANCER

MEME KANSERİ TANISI ALMIŞ KADINLARDA SOSYODEMOGRAFİK VERİLER, MEME YOĞUNLUĞU, MENOPOZ VARLIĞI İLE HEMATOLOJİK VE HİSTOPATOLOJİK BULGULARIN DEĞERLENDİRİLMESİ

Pages
23–34
Publication Date
2022-10-12
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

While the mean body mass index (BMI) of premenopausal patients was 26.53 ± 3.05 kg / m2, the BMI of postmenopausal patients was 29.63 ± 5.60 kg / m2 and their BMI was statistically significantly higher than that of premenopausal patients. (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Breast cancer is the most common type of cancer in women and accounts for 15% of cancer-related deaths.
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Key Findings & Data:Materials and Methods: The examination, surgery and histopathological results of 154 patients who were referred to the Breast Unit and underwent mammography examination and tru-cut biopsy after the examination and diagnosed with cancer were analyzed retrospectively.
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Conclusion & Impact:While the mean body mass index (BMI) of premenopausal patients was 26.53 ± 3.05 kg / m2, the BMI of postmenopausal patients was 29.63 ± 5.60 kg / m2 and their BMI was statistically significantly higher than that of premenopausal patients. (p
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: Breast cancer is the most common type of cancer in women and accounts for 15% of cancer-related deaths. One of the strongest risk factors of breast cancer development, as well as high breast density, factors such as age, birth, breastfeeding, hormone replacement therapy also affect cancer development. In this study, it was aimed to evaluate the effects of sociodemographic data, breast density, presence of menopause, hematological and histopathological findings in women diagnosed with breast cancer. Materials and Methods: The examination, surgery and histopathological results of 154 patients who were referred to the Breast Unit and underwent mammography examination and tru-cut biopsy after the examination and diagnosed with cancer were analyzed retrospectively. According to the mammography findings, who underwent tru-cut biopsy due to suspected cancer and subsequently diagnosed as cancer, 154 patients’ examination, surgery and histopathological results were retrospectively reviewed. 140 patients were included in the study. Breast intensity was recorded from the patients' age, education and marital status, first menstrual age, first gestational age, number of pregnancies, age of first delivery, hormone replacement therapy, and BI-RADS classification results from mammography reports. After obtaining tumor diameter, grade, lymph node metastasis and whether there was lymphovascular invasion from the histopathology report, it was divided into groups according to TNM (tumor- lymph node- metastasis) classification. Neutrophilleukocyte/lymphocyte and platelet/lymphocyte ratios were calculated from the blood count values of the patients. Results: Of the 140 patients diagnosed with breast cancer, 32 were premenopausal and 108 were postmenopausal. While the mean body mass index (BMI) of premenopausal patients was 26.53 ± 3.05 kg / m2, the BMI of postmenopausal patients was 29.63 ± 5.60 kg / m2 and their BMI was statistically significantly higher than that of premenopausal patients. (p

Özet

Amaç: Meme kanseri, kadınlarda en sık görülen kanser türüdür ve kansere bağlı ölümlerin %15’ini oluşturur.Meme kanser gelişiminin en güçlü risk faktörlerinden biri meme yoğunluğunun fazla olmasının yanı sıra yaş,doğum, emzirme, hormon replasman tedavisi gibi faktörler de kanser gelişimini etkilemektedir. Bu çalışmadameme kanseri tanısı almış kadınlarda sosyodemografik veriler, meme yoğunluğu, menopoz varlığı, hematolojikve histopatolojik bulguların değerlendirilmesi amaçlanmıştır.Materyal ve Metot: Meme Ünitesi birimine yönlendirilen ve mamografi tetkiki yapılan hastalardan, tetkiksonrasında kanser şüphesi nedeniyle tru-cut biyopsisi yapılan ve kanser tanısı alan 154 hastanın tetkik,ameliyat ve histopatolojik sonuçları retrospektif olarak incelendi. 140 hasta çalışmaya dahil edildi. Hastalarınyaşı, eğitim ve medeni durumu, ilk adet yaşı, ilk gebelik yaşı, gebelik sayısı, ilk doğum yaşı, hormon replasmantedavisi görüp görmediği ve mamografi raporlarından da BI-RADS sınıflama sonucu ile meme yoğunluğukaydedildi. Histopatoloji raporundan tümör çapı, derecesi, lenf nodu metastaz varlığı ve lenfovaskülerinvazyon olup olmadığı elde edildikten sonra TNM (tümör-lenf nodu-metastaz) sınıflamasına göre gruplaraayrıldı. Hastaların kan sayımı değerlerinden nötrofil lökosit/lenfosit oranı ve trombosit/lenfosit oranlarıhesaplandı.Bulgular: Meme kanseri tanısı alan 140 hastanın 32’si premenopozal, 108’i postmenopozal idi. Premenopozalhastaların vücut kitle indeksi (VKİ) ortalaması 26,53±3,05 kg/m2 iken, postmenopozal hastaların VKİ’nin29,63±5,60 kg/m2 olduğu ve bu hastaların VKİ’sinin premenopozal hastalarınkinden istatistiksel olarakanlamlı şekilde yüksek olduğu görüldü (p

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Cite This Article

ÜNAL, Ö., KORUKLUOĞLU, B. (2022). EVALUATION OF SOCIODEMOGRAPHIC DATA, BREAST DENSITY, PRESENCE OF MENOPAUSE AND HEMATOLOGICAL AND HISTOPATHOLOGICAL FINDINGS IN WOMEN DIAGNOSED WITH BREAST CANCER. Ankara Medical Journal, Cilt: 20 - Sayı: 1, 23–34. https://ajindex.com/articles/441844

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