Journals / Anadolu Kliniği Tıp Bilimleri Dergisi / 2018 / Cilt: 23 - Sayı: 2

Our Therapeutic Approach to Idiopathic Granulomatous Mastitis

İdiyopatik Granülomatöz Mastitte Tedavi Yaklaşımımız

Pages
88–92
Publication Date
2022-10-11
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Such combination is capable of reducing recurrence rates.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: Granulomatous mastitis is a rare disease of the breast.
📊
Key Findings & Data:In this study, we aimed to present our experience with idiopathicgranulomatous mastitis (IGM).Materials and Methods: Patients who had been treated and followed up after a diagnosis of GMat the surgical clinic of the Istanbul University Institute of Oncology between 2007 and 2017 werecategorized into two groups: those who had received steroid treatment only (Group 1), and thosewho had received steroids in combination with surgical treatment (Group 2).
💡
Conclusion & Impact:Such combination is capable of reducing recurrence rates.
🔬Design:Research Article
📍Scope:2007 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: Granulomatous mastitis is a rare disease of the breast. Initial findings during admission canbe mistaken for breast cancer. In this study, we aimed to present our experience with idiopathicgranulomatous mastitis (IGM).Materials and Methods: Patients who had been treated and followed up after a diagnosis of GMat the surgical clinic of the Istanbul University Institute of Oncology between 2007 and 2017 werecategorized into two groups: those who had received steroid treatment only (Group 1), and thosewho had received steroids in combination with surgical treatment (Group 2). The groups werecompared in terms of clinical and demographic characteristics and recurrence rates.Findings: We included a total of seventy-nine patients in our study. The mean patient age was36.41±6.93 years and the mean follow-up 57.34±20.39 months. There was no significant differencebetween the two groups in terms of mean age, age at menarche, maternal age at first delivery,and the side involved (right, left, bilateral). The disease had recurred in 19 patients in Group 1 whileno recurrence had been observed in Group 2 (p=0.001).Discussion and Conclusion: IGM is a disease that is rare but easily mistakable for breast cancer.The diagnosis necessitates confirmation through a biopsy. Steroid therapy combined with surgerycan be the first choice in the treatment of this disease, on which no consensus has yet beenreached. Such combination is capable of reducing recurrence rates.

Özet

Amaç: Granülomatöz mastit nadir görülen bir meme hastalığıdır. Müracaat bulguları meme kanseri ile karıştırılabilir. Bu çalışmada idiyopatik granülomatöz mastit (İGM) deneyimimizi sunmayı amaçladık. Gereç ve Yöntemler: İstanbul Üniversitesi Onkoloji Enstitüsü Cerrahi Polikliniği’nde granülomatöz mastit tanısı ile 2007–2017 döneminde tedavi ve takip edilmiş olan hastalar, sadece steroit tedavisi görmüş olanlar (Grup 1) ve steroit tedavisine ilaveten cerrahi tedavi görmüş olanlar (Grup 2) olarak iki gruba ayrıldı. Gruplar klinik ve demografik özellikleri ile nüks oranları açısından karşılaştırıldı. Bulgular: Çalışmamız kapsamına toplam 79 hasta alınmıştır. Hastaların ortalama yaşı 36,41±6,93 yıl, ortalama takip süresi 57,34±20,39 ay idi. İki grup arasında yaş ortalaması, ilk adet yaşı, ilk doğum yaşı ve tutulan taraf (sağ, sol, bilateral) yönünden anlamlı fark yoktu. Grup 1’de 19 hastada nüks gözlenirken Grup 2’de hiç nüks gözlenmemişti (p=0,001). Tartışma ve Sonuç: İGM nadir görülen fakat meme kanseri ile karıştırılabilen bir hastalıktır. Tanıda biyopsi ile teyit şarttır. Tedavisi konusunda henüz konsensüse varılamamış olan bu hastalıkta steroit tedavisiyle cerrahi tedavinin kombine edilmesi ilk tercih olabilir. Bu kombinasyon ile nüks oranları azaltılabilmektedir.

🔖

Cite This Article

ÜÇÜNCÜ, M. Z., BADEMLER, S. (2022). Our Therapeutic Approach to Idiopathic Granulomatous Mastitis. Anadolu Kliniği Tıp Bilimleri Dergisi, Cilt: 23 - Sayı: 2, 88–92. https://ajindex.com/articles/437723

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Akbulut S, Yilmaz D, Bakir S. Methotrexate in the management of idiopathic granulomatous mastitis: review of 108 published cases and report of four cases. Breast J. 2011;17:661–8.
  2. Karanlik H, Ozgur İ, Simsek S, Fathalizadeha A, Tukenmez M, Sahin D, et al. Can steroids plus surgery become a first-line treatment of idiopathic granulomatous mastitis? Breast Care. 2014;9:338–42.
  3. Sheybani F, Sarvghad MR, Naderi HR, Gharib M. Treatment for and clinical characteristics of granulomatous mastitis. Obstet Gynecol. 2015;125;4;801–7.
  4. Skandarajah A, Marley L. Idiopathic granulomatous mastitis: a medical or surgical disease of the breast? ANZ J Surg. 2015;85:979–82.
  5. Akcan A, Akyildiz H, Deneme MA, Akgun H, Aritas Y. Granulomatous lobular mastitis: a complex diagnostic and therapeutic problem. World J Surg. 2006;30:1403–9.
  6. Dursun M, Yilmaz S, Yahyayev A, Salmaslioglu A, Yavuz E, Igci A, et al. Multimodality imaging features of idiopathic granulomatous mastitis: outcome of 12 years of experience. Radiol Med. 2012;117:529–38.
  7. Jorgensen MB, Nielsen DM. Diagnosis and treatment of granulomatous mastitis. Am J Med. 1992;93:97–101.
  8. Han BK, Choe YH, Park JM, Moon WK, Ko YH, Yang JH, et al. Granulomatous mastitis: mammographic and sonographic appearances. AJR Am J Roentgenol. 1999;173:317–20.
  9. Altintoprak F, Kivilcim T, Yalkin O, Uzunoglu Y, Kahyaoglu Z, Dilek ON. Topical steroids are effective in the treatment of idiopathic granulomatous mastitis. World J Surg. 2015;39:2718–23.
  10. Heer R, Shrimankar J, Griffith CDM. Granulomatous mastitis can mimic breast cancer on clinical, radiological or cytological examination: a cautionary tale. Breast. 2003;12:283–6.
  11. Azlina AF, Ariza Z, Arni T, Hisham AN. Chronic granulomatous mastitis: diagnostic and therapeutic considerations. World J Surg. 2003;27:515–8.
  12. Gurleyik G, Aktekin A, Aker F, Karagulle H, Saglamc A. Medical and surgical treatment of idiopathic granulomatous lobular mastitis: a benign inflammatory disease mimicking invasive carcinoma. J Breast Cancer. 2012;15:119–23.
  13. Ocal K, Dag A, Turkmenoglu O, Kara T, Seyit H, Konca K. Granulomatous mastitis: clinical, pathological features, and management. Breast J. 2010;16:176–82.
  14. Erozgen F, Ersoy YE, Akaydin M, Memmi N, Celik AS, Celebi F, et al. Corticosteroid treatment and timing of surgery in idiopathic granulomatous mastitis confusing with breast carcinoma. Breast Cancer Res Treat. 2010;123:447–52.
  15. Sato N, Yamashita H, Kozaki N, Watanabe Y, Ohtsuka T, Kuroki S, et al. Granulomatous mastiti