Journals / Akademik Acil Tıp Dergisi / 2010 / Cilt: 9 - Sayı: 2

Metformine bağlı ölümcül laktik asidoz

Fatal lactic acidosis due to metformin

Pages
112–112
Publication Date
2022-10-12
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Thus mortality rates can be lessened.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A 55-year-old male patient was admitted to emergency department.
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Key Findings & Data:He ingested 50-60 tablets of 850 mg metformin for suicidal attempt.
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Conclusion & Impact:Thus mortality rates can be lessened.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A 55-year-old male patient was admitted to emergency department. He ingested 50-60 tablets of 850 mg metformin for suicidal attempt. Blood glucose 352 mg/dL, ALT 52 IU/L, AST 39 IU/L, LDH 441 IU/L, lactate over 181 mg/dL, pH 7.29, pO2 44 mmHg, pCO2 39 mmHg, HCO3 18 mEq/L, oxygen saturation was 74%. Bicarbonate was given by intravenous push at a dose of 1 mEq/kg body weight and the patient was transferred to the intensive care unit. Haemofiltration was performed for lactic acidosis. Haemofiltration should be initiated immediately in patients with acidosis due to metformin. Thus mortality rates can be lessened.

Özet

55 yaşında erkek hasta acil servisimize başvurdu. Metformin 850 mg tabletten 50-60 adet suisid için almıştı.Kan şekeri 352 mg/dL, ALT 52 IU/L, AST 39 IU/L, LDH 441 IU/L,laktat181 mg/dL, pH 7.29, pO2 44 mmHg, pCO2 39 mmHg, HCO3 18 mEq/L, oxygen satürasyonu %74 idi. Hataya 1 mEq/kg dozdan bikarbonat verildi ve yoğun bakıma alındı. Laktik asidoz için hemodializ uygulandı. Hemofiltrasyon metformine bağlı laktik asidozun tedavisinde öncelikle yapılmalıdır. Böylelikle mortalite azaltılabilir.

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Cite This Article

TAŞKIRAN, B., GÜLDİKEN, S., KAVALCI, G., KAVALCI, C. (2022). Metformine bağlı ölümcül laktik asidoz. Akademik Acil Tıp Dergisi, Cilt: 9 - Sayı: 2, 112–112. https://ajindex.com/articles/431742

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References (6)

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